GO_0051897 | OmnibusX

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	ANGPT1-TEK	ANGP1_HUMAN - TIE2_HUMAN	Ligand-Receptor	Signaling by Angiopoietin
2	CCL19-CCR7	CCL19_HUMAN - CCR7_HUMAN	Ligand-Receptor	Signaling by Chemokines
3	CCL21-CCR7	CCL21_HUMAN - CCR7_HUMAN	Ligand-Receptor	Signaling by Chemokines
4	CX3CL1-CX3CR1	X3CL1_HUMAN - CX3C1_HUMAN	Ligand-Receptor	Signaling by Chemokines
5	EGF-EGFR	EGF_HUMAN - EGFR_HUMAN	Ligand-Receptor	Signaling by Epidermal growth factor
6	F2-F2R	THRB_HUMAN - PAR1_HUMAN	Ligand-Receptor	Adhesion by Prothrombin
7	FGF2-FGFR1	FGF2_HUMAN - FGFR1_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
8	FGF2-FGFR3	FGF2_HUMAN - FGFR3_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
9	FN1-ITGA10+ITGB1	FINC_HUMAN -	Adhesion-Adhesion	Adhesion by Fibronectin
10	FN1-ITGA11+ITGB1	FINC_HUMAN -	Adhesion-Adhesion	Adhesion by Fibronectin
11	FN1-ITGA2+ITGB1	FINC_HUMAN -	Adhesion-Adhesion	Adhesion by Fibronectin
12	FN1-ITGA3+ITGB1	FINC_HUMAN -	Adhesion-Adhesion	Adhesion by Fibronectin
13	FN1-ITGA4+ITGB1	FINC_HUMAN -	Adhesion-Adhesion	Adhesion by Fibronectin
14	FN1-ITGA5+ITGB1	FINC_HUMAN -	Adhesion-Adhesion	Adhesion by Fibronectin
15	FN1-ITGA8+ITGB1	FINC_HUMAN -	Adhesion-Adhesion	Adhesion by Fibronectin
16	FN1-ITGAV+ITGB1	FINC_HUMAN -	Adhesion-Adhesion	Adhesion by Fibronectin
17	GAS6-AXL	GAS6_HUMAN - UFO_HUMAN	Ligand-Receptor	Signaling by Growth arrest
18	GAS6-MERTK	GAS6_HUMAN - MERTK_HUMAN	Ligand-Receptor	Signaling by Growth arrest
19	GAS6-TYRO3	GAS6_HUMAN - TYRO3_HUMAN	Ligand-Receptor	Signaling by Growth arrest
20	HBEGF-EGFR	HBEGF_HUMAN - EGFR_HUMAN	Ligand-Receptor	Signaling by Epidermal growth factor
21	HBEGF-ERBB4	HBEGF_HUMAN - ERBB4_HUMAN	Ligand-Receptor	Signaling by Epidermal growth factor
22	IGF1-GPC3+IGF1R	IGF1_HUMAN -	Ligand-Receptor	Signaling by Insulin-like growth factor
23	IGF1-IGF1R	IGF1_HUMAN - IGF1R_HUMAN	Ligand-Receptor	Signaling by Insulin-like growth factor
24	IGF2-IGF1R	IGF2_HUMAN - IGF1R_HUMAN	Ligand-Receptor	Signaling by Insulin-like growth factor
25	INS-INSR	INS_HUMAN - INSR_HUMAN	Ligand-Receptor	Signaling by Insulin-like precursor
26	PDGFA-PDGFRA	PDGFA_HUMAN - PGFRA_HUMAN	Ligand-Receptor	Signaling by Platelet-derived growth factor
27	PDGFB-PDGFRA	PDGFB_HUMAN - PGFRA_HUMAN	Ligand-Receptor	Signaling by Platelet-derived growth factor
28	PDGFB-PDGFRA+PDGFRB	PDGFB_HUMAN -	Ligand-Receptor	Signaling by Platelet-derived growth factor
29	PDGFB-PDGFRB	PDGFB_HUMAN - PGFRB_HUMAN	Ligand-Receptor	Signaling by Platelet-derived growth factor
30	PDGFC-PDGFRA	PDGFC_HUMAN - PGFRA_HUMAN	Ligand-Receptor	Signaling by Platelet-derived growth factor
31	PDGFD-PDGFRA+PDGFRB	PDGFD_HUMAN -	Ligand-Receptor	Signaling by Platelet-derived growth factor
32	PDGFD-PDGFRB	PDGFD_HUMAN - PGFRB_HUMAN	Ligand-Receptor	Signaling by Platelet-derived growth factor
33	SEMA4D-PLXNB1	SEM4D_HUMAN - PLXB1_HUMAN	Ligand-Receptor	Signaling by Semaphorin
34	TGFB1-TGFBR1+TGFBR2	TGFB1_HUMAN -	Ligand-Receptor	Signaling by Transforming growth factor
35	TGFB2-TGFBR1+TGFBR2	TGFB2_HUMAN -	Ligand-Receptor	Signaling by Transforming growth factor
36	THBS1-ITGA3+ITGB1	TSP1_HUMAN -	Ligand-Receptor	Adhesion by Thrombospondin

II. Literature review

[source]

Name	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
ID	GO_0051897
collection_id	Biological process
Exact synonym	positive regulation of PI3K-PKB/Akt pathway, positive regulation of PI3K/Akt signal transduction, positive regulation of PI3K/PKB signal transduction, positive regulation of phosphatidylinositol 3-kinase signaling/protein kinase B signal transduction
Description	Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase/protein kinase B signal transduction.
Related synonym	positive regulation of AKT signaling cascade, positive regulation of AKT signalling cascade, positive regulation of PKB signaling cascade, positive regulation of PKB signalling cascade, positive regulation of protein kinase B signaling, positive regulation of protein kinase B signaling cascade, positive regulation of protein kinase B signalling cascade, up regulation of protein kinase B signaling cascade, up-regulation of protein kinase B signaling cascade, upregulation of protein kinase B signaling cascade
External URL
Genes	CCL19 ADAM8 ENG PLXNB1 KIT THPO CCDC88A PDGFA F2RL1 NCF1 MYOC DDR1 OSM RGL2 GAS6 P2RY12 HCLS1 CSF1R PDPK1 INS SESN2 MFHAS1 MTOR URS00004E5112_9606 AKR1C3 HBEGF IGFBP5 IRS1 PARK7 EXTL3 STOX1 RICTOR AXL FSHR CCL3 CD28 FERMT2 RELN THBS1 RET PDGFRA BECN1 NTRK3 GATA3 CX3CL1 SIRT1 PIK3AP1 TGFBR1 AKR1C2 MTDH PIK3CA FGFR1 PDGFB CCL21 TYRO3 NTRK2 SEMA5A CAT NTRK1 PTK2 HPSE FGF2 AGT CCL5 PDGFD ROR2 RAMP3 LEP IGF2 P2RX4 CD19 STK3 IRS2 WNT16 ERBB3 NTS EPHA8 MEIS3 MAZ SRC HCST HGF ARRB2 NDP GRM2 TGFB1 CDC42 MERTK EGFR abeta-42-oligomer_human PPARD URS00001F1DA8_9606 TGFB2 ERFE FGR URS0000812128_9606 NRXN1 URS000039ED8D_9606 UBE3A SEMA3E CHI3L1 ANGPT1 ERBB4 EGF KDR CBL CCR7 FAM110C F2R ITGB1 INSR BTBD10 FN1 CX3CR1 BAG4 MUSK PRR5L URS00002524E1_9606 RTN4 PDGFC GPER1 URS0000338542_9606 FLT1 SOX9 URS000040780F_9606 FLT3 LIN28A CSF3 CPNE1 HIP1 SELP IGF1R PTK2B C1QTNF1 PRKD1 IL18 C1QTNF12 PTPRJ CASS4 NOX4 ITGB1BP1 PDGFRB IL26 TSPYL5 NEDD4 MYDGF IGF1 TCF7L2 VAV3 DDR2 JAK2 FGFR3 PIK3CG PINK1 TNFSF11 UNC5B AMBRA1 PHB1 GPX1 SERPINA12 SPRY2 URS00002F4D78_9606 TMEM100 TNF PTPN6 TREM2 C1QBP RASD2 DCN SEMA4D TXN GCNT2 amy3-receptor_human NKX3-1 GDF15 ROR1 CALCR PRR5 GH1 FER OSBPL8 VAV2 HAX1 GFRAL PIK3R5 TEK MST1R TPBG URS00003F2D94_9606 F2 LTK MYORG

positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction

I. Involved cell-cell interactions

II. Literature review