SEMA3E | OmnibusX

Name	Number of supported studies	Average coverage
oligodendrocyte precursor cell	10 studies	42% ± 17%	Explore
type I pneumocyte	7 studies	31% ± 11%	Explore
glutamatergic neuron	5 studies	25% ± 8%	Explore
retinal bipolar neuron	4 studies	27% ± 6%	Explore
GABAergic neuron	3 studies	35% ± 11%	Explore
astrocyte	3 studies	40% ± 18%	Explore
rod bipolar cell	3 studies	65% ± 9%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	26% ± 9%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	98%	514.41	241 / 245	88%	5.08	444 / 502
breast	100%	450.64	458 / 459	73%	6.35	815 / 1118
lung	88%	258.68	508 / 578	51%	3.31	594 / 1155
bladder	100%	958.19	21 / 21	31%	1.31	157 / 504
brain	80%	193.42	2119 / 2642	49%	4.16	346 / 705
esophagus	77%	658.57	1108 / 1445	40%	3.50	74 / 183
intestine	94%	461.95	904 / 966	17%	1.01	91 / 527
thymus	46%	53.90	302 / 653	61%	3.64	369 / 605
stomach	77%	160.72	277 / 359	29%	1.41	82 / 286
skin	61%	99.98	1107 / 1809	28%	3.31	134 / 472
pancreas	17%	49.24	57 / 328	71%	3.44	127 / 178
adipose	85%	237.42	1028 / 1204	0%	0	0 / 0
uterus	52%	82.01	89 / 170	28%	2.10	127 / 459
blood vessel	72%	176.89	958 / 1335	0%	0	0 / 0
ovary	10%	15.06	18 / 180	54%	4.28	232 / 430
liver	2%	2.74	5 / 226	19%	2.21	79 / 406
kidney	12%	17.37	11 / 89	6%	0.46	57 / 901
eye	0%	0	0 / 0	10%	0.25	8 / 80
tonsil	0%	0	0 / 0	7%	0.29	3 / 45
adrenal gland	0%	0.28	1 / 258	4%	0.40	9 / 230
heart	3%	2.42	24 / 861	0%	0	0 / 0
muscle	2%	2.01	17 / 803	0%	0	0 / 0
spleen	0%	0.29	1 / 241	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
peripheral blood	0%	0	0 / 929	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0001755	Biological process	neural crest cell migration
GO_0001953	Biological process	negative regulation of cell-matrix adhesion
GO_0021828	Biological process	gonadotrophin-releasing hormone neuronal migration to the hypothalamus
GO_0050919	Biological process	negative chemotaxis
GO_0016525	Biological process	negative regulation of angiogenesis
GO_0002040	Biological process	sprouting angiogenesis
GO_0001569	Biological process	branching involved in blood vessel morphogenesis
GO_0030335	Biological process	positive regulation of cell migration
GO_0051897	Biological process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0008360	Biological process	regulation of cell shape
GO_0071526	Biological process	semaphorin-plexin signaling pathway
GO_0043524	Biological process	negative regulation of neuron apoptotic process
GO_0050808	Biological process	synapse organization
GO_0007411	Biological process	axon guidance
GO_0005615	Cellular component	extracellular space
GO_0005576	Cellular component	extracellular region
GO_0005886	Cellular component	plasma membrane
GO_0048018	Molecular function	receptor ligand activity
GO_0030215	Molecular function	semaphorin receptor binding
GO_0045499	Molecular function	chemorepellent activity
GO_0005515	Molecular function	protein binding

Gene name	SEMA3E
Protein name	Semaphorin-3E Semaphorin 3E
Synonyms	SEMAH KIAA0331
Description	FUNCTION: Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis, both during embryogenesis and after birth. Can down-regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Plays an important role in ensuring the specificity of synapse formation (By similarity). .
Accessions	A0A2R8YCX5 ENST00000642232.1 ENST00000453333.2 ENST00000643230.2 [O15041-1] O15041 F8WCZ5

SEMA3E report