Interactors | Protein name | Directionality | Classification | |
|---|---|---|---|---|
| 1 | CD274-CD80 | PD1L1_HUMAN - CD80_HUMAN | Ligand-Receptor | |
| 2 | WNT1-SFRP2 | WNT1_HUMAN - SFRP2_HUMAN | Ligand-Ligand | Signaling by WNT inhibition |
| 3 | WNT2-SFRP2 | WNT2_HUMAN - SFRP2_HUMAN | Ligand-Ligand | Signaling by WNT inhibition |
| 4 | WNT3-SFRP2 | WNT3_HUMAN - SFRP2_HUMAN | Ligand-Ligand | Signaling by WNT inhibition |
| 5 | WNT3A-SFRP2 | WNT3A_HUMAN - SFRP2_HUMAN | Ligand-Ligand | Signaling by WNT inhibition |
| 6 | WNT4-SFRP2 | WNT4_HUMAN - SFRP2_HUMAN | Ligand-Ligand | Signaling by WNT inhibition |
| 7 | WNT5A-SFRP2 | WNT5A_HUMAN - SFRP2_HUMAN | Ligand-Ligand | Signaling by WNT inhibition |
| 8 | WNT7A-SFRP2 | WNT7A_HUMAN - SFRP2_HUMAN | Ligand-Ligand | Signaling by WNT inhibition |
| 9 | WNT7B-SFRP2 | WNT7B_HUMAN - SFRP2_HUMAN | Ligand-Ligand | Signaling by WNT inhibition |
| 10 | WNT8A-SFRP2 | WNT8A_HUMAN - SFRP2_HUMAN | Ligand-Ligand | Signaling by WNT inhibition |
| 11 | WNT8B-SFRP2 | WNT8B_HUMAN - SFRP2_HUMAN | Ligand-Ligand | Signaling by WNT inhibition |
| 12 | WNT9A-SFRP2 | WNT9A_HUMAN - SFRP2_HUMAN | Ligand-Ligand | Signaling by WNT inhibition |
| 13 | WNT9B-SFRP2 | WNT9B_HUMAN - SFRP2_HUMAN | Ligand-Ligand | Signaling by WNT inhibition |
| Name | receptor ligand activity |
| ID | GO_0048018 |
| collection_id | Molecular function |
| Alternative ID | GO:0071884 |
| Exact synonym | signaling molecule, signaling receptor ligand activity |
| Description | The activity of a gene product that interacts with a receptor to effect a change in the activity of the receptor. Ligands may be produced by the same cell that expresses the receptor. Ligands may also be expressed at the plasma membrane of an adjacent cell (e.g. Notch ligands) or be secreted and diffuse extracellularly from their point of origin to the receiving cell (e.g. interleukins). |
| External URL | |
| Genes | vegfa_human-1EGFGREM2ULBP1EREGGPNMBCCL26SFRP2NRG1HMGB1MICAZP3CLEC2BNBL1TNFSF13IGF2WNT10AHSPA1AGAS6WNT9BAPPNRG3CD80CXCL13WNT4NTSNRG4GREM1TGFACD86HBEGFLRPAP1BTCDLL1CCL11WNT8ACD274TAFA4IL17DWNT5ATAFA2WNT3PTHDLL4WNT9ARELNSEMA4DCTSGTNFSF13BCCL24IAPPVEGFAWNT7BGPR15LGF2RL2PGLYRP1WNT2TAFA3TNFSF12TAFA1WNT7ATAFA5SEMA3EWNT10BWNT1WNT8BWNT3ACD70AREG |