WNT10A report

I. Expression across cell types

Insufficient scRNA-seq data for expression of WNT10A at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of WNT10A at tissue level.

III. Associated gene sets

GO_0071560Biological processcellular response to transforming growth factor beta stimulus
GO_0048730Biological processepidermis morphogenesis
GO_0042476Biological processodontogenesis
GO_0010628Biological processpositive regulation of gene expression
GO_0031069Biological processhair follicle morphogenesis
GO_0043586Biological processtongue development
GO_0060070Biological processcanonical Wnt signaling pathway
GO_0030182Biological processneuron differentiation
GO_0045165Biological processcell fate commitment
GO_0042487Biological processregulation of odontogenesis of dentin-containing tooth
GO_0001942Biological processhair follicle development
GO_0014033Biological processneural crest cell differentiation
GO_0048733Biological processsebaceous gland development
GO_0043588Biological processskin development
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0048018Molecular functionreceptor ligand activity
GO_0005109Molecular functionfrizzled binding
GO_0005125Molecular functioncytokine activity

IV. Literature review

[source]
Gene nameWNT10A
Protein nameProtein Wnt-10a
Protein Wnt
Synonyms
DescriptionFUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Plays a role in normal ectoderm development . Required for normal tooth development . Required for normal postnatal development and maintenance of tongue papillae and sweat ducts . Required for normal proliferation of basal cells in tongue filiform papillae, plantar epithelium and sweat ducts. Required for normal expression of keratins in tongue papillae (By similarity). Required for normal expression of KRT9 in foot plant epithelium . Required for normal hair follicle function . .

FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. .

FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. .

FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. .

FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. .

AccessionsENST00000458582.1
Q05BQ6
A0A2H4GYZ1
Q9GZT5
A0A2K8FR47
ENST00000258411.8
H7BZB8