neural crest cell differentiation

I. Involved cell types

Genes
Cell types
No. of supported studies
Group 1
SMAD4SIX1RPS7
epithelial cell
5 studies
Group 2
LRP6EXT1MEF2CFBXL17
endothelial cellastrocyteoligodendrocyte precursor cellglutamatergic neuroninterneuron
15 studies
Group 3
OTUD5
epithelial cellciliated cellplasma cell
11 studies
Group 4
FRZB
pericytesmooth muscle cellfibroblast
59 studies

II. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1WNT10A-FRZBWN10A_HUMAN - SFRP3_HUMANLigand-LigandSignaling by WNT inhibition
2WNT10A-FZD1+LRP6WN10A_HUMAN - Ligand-ReceptorSignaling by WNT
3WNT10A-FZD5+LRP6WN10A_HUMAN - Ligand-ReceptorSignaling by WNT
4WNT10A-FZD7+LRP6WN10A_HUMAN - Ligand-ReceptorSignaling by WNT
5WNT10A-FZD8+LRP6WN10A_HUMAN - Ligand-ReceptorSignaling by WNT

III. Literature review

[source]
Nameneural crest cell differentiation
IDGO_0014033
collection_id

Biological process

Description

The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.

External URL
Genes
RPS7EXT1SMAD4WNT10AFRZBOTUD5MEF2CSIX1FBXL17HTR2BLRP6scf-fbxl17_human