I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| pancreatic A cell | 3 studies | 32% ± 10% | |
| type B pancreatic cell | 3 studies | 37% ± 18% | |
| basal cell | 3 studies | 21% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| pancreatic A cell | 3 studies | 32% ± 10% | |
| type B pancreatic cell | 3 studies | 37% ± 18% | |
| basal cell | 3 studies | 21% ± 4% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| pancreas | 3 studies | 27% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 92% | 1027.11 | 226 / 245 | 95% | 6.62 | 476 / 502 |
| adrenal gland | 99% | 1124.31 | 256 / 258 | 60% | 13.29 | 138 / 230 |
| uterus | 75% | 775.98 | 128 / 170 | 76% | 11.94 | 348 / 459 |
| ovary | 97% | 3063.96 | 174 / 180 | 53% | 3.67 | 226 / 430 |
| pancreas | 63% | 211.30 | 208 / 328 | 85% | 21.03 | 152 / 178 |
| stomach | 76% | 432.24 | 272 / 359 | 64% | 4.33 | 184 / 286 |
| skin | 72% | 2617.84 | 1296 / 1809 | 51% | 4.21 | 239 / 472 |
| intestine | 49% | 283.35 | 476 / 966 | 73% | 5.24 | 384 / 527 |
| breast | 46% | 209.46 | 213 / 459 | 75% | 8.83 | 834 / 1118 |
| bladder | 57% | 584.00 | 12 / 21 | 60% | 5.10 | 303 / 504 |
| esophagus | 40% | 602.68 | 573 / 1445 | 77% | 8.82 | 140 / 183 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.71 | 1 / 1 |
| eye | 0% | 0 | 0 / 0 | 96% | 9.26 | 77 / 80 |
| thymus | 51% | 199.74 | 335 / 653 | 44% | 5.53 | 266 / 605 |
| lung | 29% | 69.31 | 168 / 578 | 63% | 6.26 | 724 / 1155 |
| tonsil | 0% | 0 | 0 / 0 | 89% | 22.19 | 40 / 45 |
| liver | 20% | 74.08 | 46 / 226 | 43% | 4.04 | 173 / 406 |
| kidney | 28% | 123.20 | 25 / 89 | 10% | 0.42 | 86 / 901 |
| brain | 24% | 77.35 | 637 / 2642 | 13% | 0.79 | 93 / 705 |
| muscle | 30% | 92.43 | 241 / 803 | 0% | 0 | 0 / 0 |
| adipose | 19% | 65.51 | 224 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.08 | 1 / 29 |
| peripheral blood | 3% | 5.93 | 24 / 929 | 0% | 0 | 0 / 0 |
| spleen | 1% | 1.58 | 2 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 1% | 3.60 | 11 / 1335 | 0% | 0 | 0 / 0 |
| heart | 0% | 0.21 | 1 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0032349 | Biological process | positive regulation of aldosterone biosynthetic process |
| GO_0097190 | Biological process | apoptotic signaling pathway |
| GO_0060231 | Biological process | mesenchymal to epithelial transition |
| GO_0001658 | Biological process | branching involved in ureteric bud morphogenesis |
| GO_0001837 | Biological process | epithelial to mesenchymal transition |
| GO_0071560 | Biological process | cellular response to transforming growth factor beta stimulus |
| GO_0010894 | Biological process | negative regulation of steroid biosynthetic process |
| GO_0061205 | Biological process | paramesonephric duct development |
| GO_0072162 | Biological process | metanephric mesenchymal cell differentiation |
| GO_0010629 | Biological process | negative regulation of gene expression |
| GO_0061045 | Biological process | negative regulation of wound healing |
| GO_0072033 | Biological process | renal vesicle formation |
| GO_0051496 | Biological process | positive regulation of stress fiber assembly |
| GO_0022407 | Biological process | regulation of cell-cell adhesion |
| GO_0030237 | Biological process | female sex determination |
| GO_0001822 | Biological process | kidney development |
| GO_0001889 | Biological process | liver development |
| GO_0061184 | Biological process | positive regulation of dermatome development |
| GO_0043410 | Biological process | positive regulation of MAPK cascade |
| GO_0009267 | Biological process | cellular response to starvation |
| GO_0140013 | Biological process | meiotic nuclear division |
| GO_0045669 | Biological process | positive regulation of osteoblast differentiation |
| GO_2000066 | Biological process | positive regulation of cortisol biosynthetic process |
| GO_0060070 | Biological process | canonical Wnt signaling pathway |
| GO_0060748 | Biological process | tertiary branching involved in mammary gland duct morphogenesis |
| GO_2000180 | Biological process | negative regulation of androgen biosynthetic process |
| GO_0060008 | Biological process | Sertoli cell differentiation |
| GO_0061369 | Biological process | negative regulation of testicular blood vessel morphogenesis |
| GO_0001838 | Biological process | embryonic epithelial tube formation |
| GO_0048599 | Biological process | oocyte development |
| GO_0030182 | Biological process | neuron differentiation |
| GO_0061180 | Biological process | mammary gland epithelium development |
| GO_0072034 | Biological process | renal vesicle induction |
| GO_2000019 | Biological process | negative regulation of male gonad development |
| GO_0045165 | Biological process | cell fate commitment |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0032967 | Biological process | positive regulation of collagen biosynthetic process |
| GO_0060129 | Biological process | thyroid-stimulating hormone-secreting cell differentiation |
| GO_2000225 | Biological process | negative regulation of testosterone biosynthetic process |
| GO_0045836 | Biological process | positive regulation of meiotic nuclear division |
| GO_0030325 | Biological process | adrenal gland development |
| GO_0051145 | Biological process | smooth muscle cell differentiation |
| GO_0051894 | Biological process | positive regulation of focal adhesion assembly |
| GO_2001234 | Biological process | negative regulation of apoptotic signaling pathway |
| GO_0008584 | Biological process | male gonad development |
| GO_0045596 | Biological process | negative regulation of cell differentiation |
| GO_0060126 | Biological process | somatotropin secreting cell differentiation |
| GO_0030336 | Biological process | negative regulation of cell migration |
| GO_0035567 | Biological process | non-canonical Wnt signaling pathway |
| GO_1904238 | Biological process | pericyte cell differentiation |
| GO_0072174 | Biological process | metanephric tubule formation |
| GO_0008585 | Biological process | female gonad development |
| GO_0030501 | Biological process | positive regulation of bone mineralization |
| GO_0042445 | Biological process | hormone metabolic process |
| GO_0033080 | Biological process | immature T cell proliferation in thymus |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0040037 | Biological process | negative regulation of fibroblast growth factor receptor signaling pathway |
| GO_0072273 | Biological process | metanephric nephron morphogenesis |
| GO_0008543 | Biological process | fibroblast growth factor receptor signaling pathway |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0030666 | Cellular component | endocytic vesicle membrane |
| GO_0005796 | Cellular component | Golgi lumen |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0031012 | Cellular component | extracellular matrix |
| GO_0009986 | Cellular component | cell surface |
| GO_0005788 | Cellular component | endoplasmic reticulum lumen |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0048018 | Molecular function | receptor ligand activity |
| GO_0003714 | Molecular function | transcription corepressor activity |
| GO_0005109 | Molecular function | frizzled binding |
| GO_0005125 | Molecular function | cytokine activity |
| Gene name | WNT4 |
| Protein name | Protein Wnt Protein Wnt-4 |
| Synonyms | UNQ426/PRO864 |
| Description | FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in the embryonic development of the urogenital tract and the lung . Required for normal mesenchyme to epithelium transition during embryonic kidney development. Required for the formation of early epithelial renal vesicles during kidney development (By similarity). Required for normal formation of the Mullerian duct in females, and normal levels of oocytes in the ovaries . Required for normal down-regulation of 3 beta-hydroxysteroid dehydrogenase in the ovary . Required for normal lung development and for normal patterning of trachael cartilage rings (By similarity). . FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. . FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. . FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. . |
| Accessions | ENST00000290167.11 [P56705-1] ENST00000441048.1 B1AJZ6 H0Y663 Q8IUM6 P56705 ENST00000415567.1 |
