epithelial to mesenchymal transition

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1NCAM1-FGFR1NCAM1_HUMAN - FGFR1_HUMANLigand-ReceptorSignaling by Fibroblast growth factor
2TGFB1-ACVR1+TGFBR2TGFB1_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
3TGFB1-TGFBR1+TGFBR2TGFB1_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
4TGFB1-TGFBR3TGFB1_HUMAN - TGBR3_HUMANLigand-ReceptorSignaling by Transforming growth factor
5TGFB2-ACVR1+TGFBR2TGFB2_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
6TGFB2-TGFBR1+TGFBR2TGFB2_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
7TGFB2-TGFBR3TGFB2_HUMAN - TGBR3_HUMANLigand-ReceptorSignaling by Transforming growth factor

II. Literature review

[source]
Nameepithelial to mesenchymal transition
IDGO_0001837
collection_id

Biological process

Exact synonym

EMT, epithelial-mesenchymal transition, mesenchymal cell differentiation from epithelial cell

Description

A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.

External URL
Genes