AMELX | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of AMELX at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	28%	0.59	270 / 966	30%	0.85	157 / 527
prostate	50%	1.63	122 / 245	2%	0.22	8 / 502
stomach	21%	0.36	74 / 359	28%	0.96	80 / 286
uterus	35%	0.58	59 / 170	3%	0.61	16 / 459
bladder	24%	0.62	5 / 21	10%	5.08	52 / 504
muscle	34%	0.78	272 / 803	0%	0	0 / 0
thymus	34%	0.61	219 / 653	0%	0.00	1 / 605
lung	30%	0.58	171 / 578	4%	0.17	44 / 1155
brain	31%	1.37	830 / 2642	1%	0.08	5 / 705
ovary	31%	0.54	55 / 180	0%	1.27	2 / 430
adipose	31%	0.60	369 / 1204	0%	0	0 / 0
blood vessel	24%	0.53	322 / 1335	0%	0	0 / 0
esophagus	20%	0.36	293 / 1445	3%	0.05	6 / 183
breast	20%	0.40	91 / 459	1%	0.26	15 / 1118
heart	20%	0.40	176 / 861	0%	0	0 / 0
kidney	18%	0.39	16 / 89	1%	0.13	7 / 901
skin	13%	0.25	243 / 1809	0%	0.03	2 / 472
spleen	9%	0.17	21 / 241	0%	0	0 / 0
adrenal gland	7%	0.11	17 / 258	0%	0.27	1 / 230
pancreas	5%	0.07	15 / 328	2%	0.06	4 / 178
peripheral blood	5%	0.09	44 / 929	0%	0	0 / 0
liver	4%	0.07	8 / 226	0%	0	0 / 406
eye	0%	0	0 / 0	1%	0.06	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0042475	Biological process	odontogenesis of dentin-containing tooth
GO_0007584	Biological process	response to nutrient
GO_0001837	Biological process	epithelial to mesenchymal transition
GO_0001649	Biological process	osteoblast differentiation
GO_0007165	Biological process	signal transduction
GO_0002062	Biological process	chondrocyte differentiation
GO_0070172	Biological process	positive regulation of tooth mineralization
GO_0007155	Biological process	cell adhesion
GO_0032967	Biological process	positive regulation of collagen biosynthetic process
GO_0031214	Biological process	biomineral tissue development
GO_0034505	Biological process	tooth mineralization
GO_0070166	Biological process	enamel mineralization
GO_0009410	Biological process	response to xenobiotic stimulus
GO_0097186	Biological process	amelogenesis
GO_0051592	Biological process	response to calcium ion
GO_0042127	Biological process	regulation of cell population proliferation
GO_0005576	Cellular component	extracellular region
GO_0030139	Cellular component	endocytic vesicle
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0009986	Cellular component	cell surface
GO_0005788	Cellular component	endoplasmic reticulum lumen
GO_0030345	Molecular function	structural constituent of tooth enamel
GO_0042802	Molecular function	identical protein binding
GO_0008083	Molecular function	growth factor activity
GO_0046848	Molecular function	hydroxyapatite binding
GO_0005515	Molecular function	protein binding

Gene name	AMELX
Protein name	Amelogenin, X isoform Amelogenin
Synonyms	AMG AMGX
Description	FUNCTION: Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel.
Accessions	ENST00000348912.4 [Q99217-2] ENST00000380712.7 [Q99217-3] Q99217 B2BY28 ENST00000380714.7 [Q99217-1]

AMELX report