SLC39A10 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0030003Biological processintracellular monoatomic cation homeostasis
GO_0071578Biological processzinc ion import across plasma membrane
GO_0002903Biological processnegative regulation of B cell apoptotic process
GO_0001837Biological processepithelial to mesenchymal transition
GO_0050861Biological processpositive regulation of B cell receptor signaling pathway
GO_0015701Biological processbicarbonate transport
GO_0071577Biological processzinc ion transmembrane transport
GO_0006882Biological processintracellular zinc ion homeostasis
GO_0030890Biological processpositive regulation of B cell proliferation
GO_0016324Cellular componentapical plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0005385Molecular functionzinc ion transmembrane transporter activity
GO_0140410Molecular functionmonoatomic cation:bicarbonate symporter activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSLC39A10
Protein nameZinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10)
Solute carrier family 39 member 10
SLC39A10 protein
SynonymsZIP10
KIAA1265
DescriptionFUNCTION: Zinc-influx transporter . When associated with SLC39A6, the heterodimer formed by SLC39A10 and SLC39A6 mediates cellular zinc uptake to trigger cells to undergo epithelial-to-mesenchymal transition (EMT) . SLC39A10-SLC39A6 heterodimers play also an essentiel role in initiating mitosis by importing zinc into cells to initiate a pathway resulting in the onset of mitosis . Plays an important for both mature B-cell maintenance and humoral immune responses (By similarity). When associated with SLC39A10, the heterodimer controls NCAM1 phosphorylation and integration into focal adhesion complexes during EMT (By similarity). .

AccessionsENST00000409086.7 [Q9ULF5-1]
ENST00000359634.10 [Q9ULF5-1]
Q9ULF5
ENST00000430412.5
ENST00000444421.5
C9J0F5
ENST00000458054.1
E7EV45
ENST00000418005.1
F2Z341
ENST00000412905.1
Q05C42
E7ENT5