Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 24 studies | 38% ± 20% | |
glutamatergic neuron | 10 studies | 56% ± 22% | |
macrophage | 10 studies | 22% ± 5% | |
microglial cell | 10 studies | 34% ± 14% | |
GABAergic neuron | 9 studies | 38% ± 20% | |
neuron | 8 studies | 31% ± 11% | |
B cell | 7 studies | 23% ± 4% | |
astrocyte | 7 studies | 29% ± 15% | |
oligodendrocyte precursor cell | 7 studies | 25% ± 9% | |
CD16-negative, CD56-bright natural killer cell, human | 6 studies | 20% ± 5% | |
interneuron | 6 studies | 44% ± 24% | |
oligodendrocyte | 6 studies | 27% ± 11% | |
epithelial cell | 5 studies | 33% ± 13% | |
ciliated cell | 5 studies | 19% ± 3% | |
T cell | 4 studies | 20% ± 3% | |
natural killer cell | 4 studies | 20% ± 4% | |
conventional dendritic cell | 4 studies | 19% ± 6% | |
myeloid cell | 4 studies | 21% ± 6% | |
mast cell | 4 studies | 24% ± 8% | |
mesothelial cell | 4 studies | 19% ± 3% | |
dendritic cell | 4 studies | 24% ± 4% | |
basal cell | 4 studies | 22% ± 5% | |
plasmacytoid dendritic cell | 4 studies | 29% ± 10% | |
effector memory CD8-positive, alpha-beta T cell | 3 studies | 21% ± 7% | |
connective tissue cell | 3 studies | 20% ± 2% | |
GABAergic interneuron | 3 studies | 25% ± 5% | |
granule cell | 3 studies | 24% ± 7% | |
lymphocyte | 3 studies | 27% ± 0% | |
gamma-delta T cell | 3 studies | 24% ± 8% | |
fibroblast | 3 studies | 19% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 3511.30 | 2641 / 2642 | 100% | 38.06 | 703 / 705 |
thymus | 100% | 4977.05 | 653 / 653 | 99% | 64.76 | 598 / 605 |
ovary | 100% | 1595.91 | 180 / 180 | 99% | 28.91 | 425 / 430 |
breast | 100% | 1525.86 | 459 / 459 | 99% | 23.91 | 1104 / 1118 |
prostate | 100% | 1978.13 | 244 / 245 | 99% | 36.06 | 496 / 502 |
lung | 100% | 1537.56 | 576 / 578 | 98% | 20.73 | 1137 / 1155 |
intestine | 99% | 1015.20 | 958 / 966 | 95% | 18.65 | 503 / 527 |
esophagus | 94% | 729.64 | 1365 / 1445 | 98% | 19.30 | 179 / 183 |
bladder | 100% | 1050.48 | 21 / 21 | 92% | 15.52 | 465 / 504 |
adrenal gland | 100% | 2400.65 | 258 / 258 | 90% | 14.39 | 207 / 230 |
uterus | 100% | 1652.19 | 170 / 170 | 89% | 15.55 | 410 / 459 |
skin | 99% | 1672.98 | 1794 / 1809 | 90% | 19.55 | 424 / 472 |
kidney | 99% | 1041.66 | 88 / 89 | 89% | 17.81 | 806 / 901 |
pancreas | 91% | 762.31 | 298 / 328 | 96% | 16.48 | 170 / 178 |
stomach | 67% | 400.01 | 242 / 359 | 93% | 18.78 | 266 / 286 |
spleen | 100% | 2591.69 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.75 | 1 / 1 |
adipose | 100% | 1487.64 | 1203 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 99% | 1036.08 | 1323 / 1335 | 0% | 0 | 0 / 0 |
heart | 80% | 597.69 | 690 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 73% | 8.64 | 33 / 45 |
lymph node | 0% | 0 | 0 / 0 | 59% | 5.51 | 17 / 29 |
eye | 0% | 0 | 0 / 0 | 54% | 4.88 | 43 / 80 |
peripheral blood | 51% | 456.69 | 473 / 929 | 0% | 0 | 0 / 0 |
liver | 11% | 53.15 | 25 / 226 | 37% | 4.18 | 152 / 406 |
muscle | 32% | 167.52 | 257 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0030003 | Biological process | intracellular monoatomic cation homeostasis |
GO_0071578 | Biological process | zinc ion import across plasma membrane |
GO_0002903 | Biological process | negative regulation of B cell apoptotic process |
GO_0001837 | Biological process | epithelial to mesenchymal transition |
GO_0050861 | Biological process | positive regulation of B cell receptor signaling pathway |
GO_0015701 | Biological process | bicarbonate transport |
GO_0071577 | Biological process | zinc ion transmembrane transport |
GO_0006882 | Biological process | intracellular zinc ion homeostasis |
GO_0030890 | Biological process | positive regulation of B cell proliferation |
GO_0016324 | Cellular component | apical plasma membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0005385 | Molecular function | zinc ion transmembrane transporter activity |
GO_0140410 | Molecular function | monoatomic cation:bicarbonate symporter activity |
GO_0005515 | Molecular function | protein binding |
Gene name | SLC39A10 |
Protein name | Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10) Solute carrier family 39 member 10 SLC39A10 protein |
Synonyms | ZIP10 KIAA1265 |
Description | FUNCTION: Zinc-influx transporter . When associated with SLC39A6, the heterodimer formed by SLC39A10 and SLC39A6 mediates cellular zinc uptake to trigger cells to undergo epithelial-to-mesenchymal transition (EMT) . SLC39A10-SLC39A6 heterodimers play also an essentiel role in initiating mitosis by importing zinc into cells to initiate a pathway resulting in the onset of mitosis . Plays an important for both mature B-cell maintenance and humoral immune responses (By similarity). When associated with SLC39A10, the heterodimer controls NCAM1 phosphorylation and integration into focal adhesion complexes during EMT (By similarity). . |
Accessions | ENST00000409086.7 [Q9ULF5-1] ENST00000359634.10 [Q9ULF5-1] Q9ULF5 ENST00000430412.5 ENST00000444421.5 C9J0F5 ENST00000458054.1 E7EV45 ENST00000418005.1 F2Z341 ENST00000412905.1 Q05C42 E7ENT5 |