Name | Number of supported studies | Average coverage | |
---|---|---|---|
squamous epithelial cell | 3 studies | 30% ± 8% | |
epithelial cell | 3 studies | 19% ± 1% |
Insufficient scRNA-seq data for expression of FAM83D at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 98% | 9610.69 | 1414 / 1445 | 99% | 88.82 | 182 / 183 |
intestine | 83% | 5864.29 | 799 / 966 | 97% | 49.31 | 512 / 527 |
stomach | 61% | 4507.94 | 219 / 359 | 99% | 63.70 | 282 / 286 |
skin | 77% | 1199.73 | 1393 / 1809 | 78% | 21.23 | 368 / 472 |
bladder | 62% | 2955.76 | 13 / 21 | 92% | 48.79 | 465 / 504 |
lung | 46% | 466.42 | 266 / 578 | 85% | 55.31 | 983 / 1155 |
prostate | 60% | 1819.43 | 147 / 245 | 57% | 15.08 | 285 / 502 |
tonsil | 0% | 0 | 0 / 0 | 100% | 87.21 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 10.87 | 1 / 1 |
uterus | 2% | 21.67 | 4 / 170 | 96% | 68.33 | 442 / 459 |
ovary | 1% | 10.18 | 1 / 180 | 96% | 42.43 | 411 / 430 |
lymph node | 0% | 0 | 0 / 0 | 79% | 20.12 | 23 / 29 |
breast | 2% | 23.24 | 10 / 459 | 77% | 28.54 | 861 / 1118 |
liver | 7% | 53.22 | 15 / 226 | 59% | 13.52 | 241 / 406 |
pancreas | 0% | 1.53 | 1 / 328 | 62% | 21.54 | 110 / 178 |
blood vessel | 42% | 831.78 | 560 / 1335 | 0% | 0 | 0 / 0 |
brain | 1% | 7.87 | 30 / 2642 | 26% | 5.78 | 181 / 705 |
peripheral blood | 20% | 354.40 | 183 / 929 | 0% | 0 | 0 / 0 |
kidney | 3% | 36.58 | 3 / 89 | 14% | 2.59 | 130 / 901 |
adrenal gland | 3% | 20.69 | 7 / 258 | 13% | 2.76 | 30 / 230 |
thymus | 4% | 37.31 | 24 / 653 | 9% | 1.77 | 57 / 605 |
spleen | 7% | 45.09 | 16 / 241 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 5% | 0.57 | 4 / 80 |
adipose | 3% | 31.42 | 42 / 1204 | 0% | 0 | 0 / 0 |
heart | 2% | 20.44 | 16 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0001837 | Biological process | epithelial to mesenchymal transition |
GO_0042176 | Biological process | regulation of protein catabolic process |
GO_1902808 | Biological process | positive regulation of cell cycle G1/S phase transition |
GO_0008283 | Biological process | cell population proliferation |
GO_0070372 | Biological process | regulation of ERK1 and ERK2 cascade |
GO_0051310 | Biological process | metaphase chromosome alignment |
GO_0007165 | Biological process | signal transduction |
GO_0051301 | Biological process | cell division |
GO_1902480 | Biological process | protein localization to mitotic spindle |
GO_0032006 | Biological process | regulation of TOR signaling |
GO_0016477 | Biological process | cell migration |
GO_0097431 | Cellular component | mitotic spindle pole |
GO_0072686 | Cellular component | mitotic spindle |
GO_0045171 | Cellular component | intercellular bridge |
GO_0005829 | Cellular component | cytosol |
GO_0015630 | Cellular component | microtubule cytoskeleton |
GO_0005737 | Cellular component | cytoplasm |
GO_0005819 | Cellular component | spindle |
GO_0019901 | Molecular function | protein kinase binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0005515 | Molecular function | protein binding |
GO_0019894 | Molecular function | kinesin binding |
Gene name | FAM83D |
Protein name | Protein FAM83D (Spindle protein CHICA) Chromosome 20 open reading frame 129 (Family with sequence similarity 83 member D) |
Synonyms | C20orf129 hCG_38062 |
Description | FUNCTION: Through the degradation of FBXW7, may act indirectly on the expression and downstream signaling of MTOR, JUN and MYC . May play also a role in cell proliferation through activation of the ERK1/ERK2 signaling cascade . May also be important for proper chromosome congression and alignment during mitosis through its interaction with KIF22 . . |
Accessions | Q9H4H8 A0A087WXK8 ENST00000619850.2 [Q9H4H8-1] ENST00000619304.4 |