PPP3R1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001837Biological processepithelial to mesenchymal transition
GO_0006470Biological processprotein dephosphorylation
GO_0007507Biological processheart development
GO_0070886Biological processpositive regulation of calcineurin-NFAT signaling cascade
GO_0033173Biological processcalcineurin-NFAT signaling cascade
GO_0022011Biological processmyelination in peripheral nervous system
GO_0001569Biological processbranching involved in blood vessel morphogenesis
GO_0006606Biological processprotein import into nucleus
GO_0099149Biological processregulation of postsynaptic neurotransmitter receptor internalization
GO_0098693Biological processregulation of synaptic vesicle cycle
GO_1905665Biological processpositive regulation of calcium ion import across plasma membrane
GO_0099170Biological processpostsynaptic modulation of chemical synaptic transmission
GO_0097720Biological processcalcineurin-mediated signaling
GO_0060487Biological processlung epithelial cell differentiation
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_1905949Biological processnegative regulation of calcium ion import across plasma membrane
GO_0098978Cellular componentglutamatergic synapse
GO_0098685Cellular componentSchaffer collateral - CA1 synapse
GO_0042383Cellular componentsarcolemma
GO_0005654Cellular componentnucleoplasm
GO_0005955Cellular componentcalcineurin complex
GO_0098794Cellular componentpostsynapse
GO_0098686Cellular componenthippocampal mossy fiber to CA3 synapse
GO_0005829Cellular componentcytosol
GO_0008287Cellular componentprotein serine/threonine phosphatase complex
GO_0098688Cellular componentparallel fiber to Purkinje cell synapse
GO_0019904Molecular functionprotein domain specific binding
GO_0008597Molecular functioncalcium-dependent protein serine/threonine phosphatase regulator activity
GO_0019902Molecular functionphosphatase binding
GO_0005516Molecular functioncalmodulin binding
GO_0005509Molecular functioncalcium ion binding
GO_0005515Molecular functionprotein binding
GO_0004723Molecular functioncalcium-dependent protein serine/threonine phosphatase activity
GO_0016018Molecular functioncyclosporin A binding

IV. Literature review

[source]
Gene namePPP3R1
Protein nameCalcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1)
Protein phosphatase 3 regulatory subunit B, alpha
SynonymsCNA2
CNB
DescriptionFUNCTION: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. .

AccessionsP63098
ENST00000409377.1
F6U1T9
ENST00000409752.5
ENST00000234310.8
D3YTA9