GO_0098978 | OmnibusX

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	CBLN1+NRXN1-GRID2	- GRID2_HUMAN	Ligand-Receptor
2	CLSTN1-NRXN2	CSTN1_HUMAN - NRX2B_HUMAN	Ligand-Receptor	Signaling by Calsyntenin
3	CLSTN2-NRXN2	CSTN2_HUMAN - NRX2B_HUMAN	Ligand-Receptor	Signaling by Calsyntenin
4	CLSTN3-NRXN2	CSTN3_HUMAN - NRX2B_HUMAN	Ligand-Receptor	Signaling by Calsyntenin
5	EFNB1-EPHA4	EFNB1_HUMAN - EPHA4_HUMAN	Ligand-Receptor	Signaling by Ephrin
6	EFNB1-EPHB1	EFNB1_HUMAN - EPHB1_HUMAN	Ligand-Receptor	Signaling by Ephrin
7	EFNB1-EPHB2	EFNB1_HUMAN - EPHB2_HUMAN	Ligand-Receptor	Signaling by Ephrin
8	EFNB2-EPHA4	EFNB2_HUMAN - EPHA4_HUMAN	Ligand-Receptor	Signaling by Ephrin
9	EFNB2-EPHB1	EFNB2_HUMAN - EPHB1_HUMAN	Ligand-Receptor	Signaling by Ephrin
10	EFNB2-EPHB2	EFNB2_HUMAN - EPHB2_HUMAN	Ligand-Receptor	Signaling by Ephrin
11	EFNB3-EPHA4	EFNB3_HUMAN - EPHA4_HUMAN	Ligand-Receptor	Signaling by Ephrin
12	EFNB3-EPHB1	EFNB3_HUMAN - EPHB1_HUMAN	Ligand-Receptor	Signaling by Ephrin
13	EFNB3-EPHB2	EFNB3_HUMAN - EPHB2_HUMAN	Ligand-Receptor	Signaling by Ephrin
14	FLRT3-ADGRL3	FLRT3_HUMAN - AGRL3_HUMAN	Ligand-Receptor	Signaling by Fibronectin
15	FLRT3+TENM3-ADGRL3	- AGRL3_HUMAN	Ligand-Receptor	Signaling by Fibronectin
16	GHRL-GHSR	GHRL_HUMAN - GHSR_HUMAN	Ligand-Receptor	Signaling by Growth hormone-releasing hormone
17	GLS2+SLC1A2-GRIA1	- GRIA1_HUMAN	Ligand-Receptor	Signaling by Glutamate
18	GLS2+SLC1A2-GRIK2	- GRIK2_HUMAN	Ligand-Receptor	Signaling by Glutamate
19	GLS2+SLC1A2-GRIK2+GRIK4	-	Ligand-Receptor	Signaling by Glutamate
20	GLS2+SLC1A2-GRIK2+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
21	GLS2+SLC1A2-GRIK3	- GRIK3_HUMAN	Ligand-Receptor	Signaling by Glutamate
22	GLS2+SLC1A2-GRIK3+GRIK4	-	Ligand-Receptor	Signaling by Glutamate
23	GLS2+SLC1A2-GRIK3+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
24	GLS2+SLC1A2-GRIN1+GRIN2A	-	Ligand-Receptor	Signaling by Glutamate
25	GLS2+SLC1A2-GRIN1+GRIN2C	-	Ligand-Receptor	Signaling by Glutamate
26	GLS2+SLC1A2-GRIN1+GRIN2D	-	Ligand-Receptor	Signaling by Glutamate
27	GLS2+SLC1A2-GRM1	- GRM1_HUMAN	Ligand-Receptor	Signaling by Glutamate
28	GLS2+SLC1A2-GRM2	- GRM2_HUMAN	Ligand-Receptor	Signaling by Glutamate
29	GLS2+SLC1A2-GRM3	- GRM3_HUMAN	Ligand-Receptor	Signaling by Glutamate
30	GLS2+SLC1A2-GRM5	- GRM5_HUMAN	Ligand-Receptor	Signaling by Glutamate
31	GLS2+SLC1A6-GRIA1	- GRIA1_HUMAN	Ligand-Receptor	Signaling by Glutamate
32	GLS2+SLC1A6-GRIK2	- GRIK2_HUMAN	Ligand-Receptor	Signaling by Glutamate
33	GLS2+SLC1A6-GRIK2+GRIK4	-	Ligand-Receptor	Signaling by Glutamate
34	GLS2+SLC1A6-GRIK2+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
35	GLS2+SLC1A6-GRIK3	- GRIK3_HUMAN	Ligand-Receptor	Signaling by Glutamate
36	GLS2+SLC1A6-GRIK3+GRIK4	-	Ligand-Receptor	Signaling by Glutamate
37	GLS2+SLC1A6-GRIK3+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
38	GLS2+SLC1A6-GRIN1+GRIN2A	-	Ligand-Receptor	Signaling by Glutamate
39	GLS2+SLC1A6-GRIN1+GRIN2C	-	Ligand-Receptor	Signaling by Glutamate
40	GLS2+SLC1A6-GRIN1+GRIN2D	-	Ligand-Receptor	Signaling by Glutamate
41	GLS2+SLC1A6-GRM1	- GRM1_HUMAN	Ligand-Receptor	Signaling by Glutamate
42	GLS2+SLC1A6-GRM2	- GRM2_HUMAN	Ligand-Receptor	Signaling by Glutamate
43	GLS2+SLC1A6-GRM3	- GRM3_HUMAN	Ligand-Receptor	Signaling by Glutamate
44	GLS2+SLC1A6-GRM5	- GRM5_HUMAN	Ligand-Receptor	Signaling by Glutamate
45	GLS+SLC1A2-GRIA1	- GRIA1_HUMAN	Ligand-Receptor	Signaling by Glutamate
46	GLS+SLC1A2-GRIK2	- GRIK2_HUMAN	Ligand-Receptor	Signaling by Glutamate
47	GLS+SLC1A2-GRIK2+GRIK4	-	Ligand-Receptor	Signaling by Glutamate
48	GLS+SLC1A2-GRIK2+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
49	GLS+SLC1A2-GRIK3	- GRIK3_HUMAN	Ligand-Receptor	Signaling by Glutamate
50	GLS+SLC1A2-GRIK3+GRIK4	-	Ligand-Receptor	Signaling by Glutamate
51	GLS+SLC1A2-GRIK3+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
52	GLS+SLC1A2-GRIN1+GRIN2A	-	Ligand-Receptor	Signaling by Glutamate
53	GLS+SLC1A2-GRIN1+GRIN2C	-	Ligand-Receptor	Signaling by Glutamate
54	GLS+SLC1A2-GRIN1+GRIN2D	-	Ligand-Receptor	Signaling by Glutamate
55	GLS+SLC1A2-GRM1	- GRM1_HUMAN	Ligand-Receptor	Signaling by Glutamate
56	GLS+SLC1A2-GRM2	- GRM2_HUMAN	Ligand-Receptor	Signaling by Glutamate
57	GLS+SLC1A2-GRM3	- GRM3_HUMAN	Ligand-Receptor	Signaling by Glutamate
58	GLS+SLC1A2-GRM5	- GRM5_HUMAN	Ligand-Receptor	Signaling by Glutamate
59	GLS+SLC1A6-GRIA1	- GRIA1_HUMAN	Ligand-Receptor	Signaling by Glutamate
60	GLS+SLC1A6-GRIK2	- GRIK2_HUMAN	Ligand-Receptor	Signaling by Glutamate
61	GLS+SLC1A6-GRIK2+GRIK4	-	Ligand-Receptor	Signaling by Glutamate
62	GLS+SLC1A6-GRIK2+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
63	GLS+SLC1A6-GRIK3	- GRIK3_HUMAN	Ligand-Receptor	Signaling by Glutamate
64	GLS+SLC1A6-GRIK3+GRIK4	-	Ligand-Receptor	Signaling by Glutamate
65	GLS+SLC1A6-GRIK3+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
66	GLS+SLC1A6-GRIN1+GRIN2A	-	Ligand-Receptor	Signaling by Glutamate
67	GLS+SLC1A6-GRIN1+GRIN2C	-	Ligand-Receptor	Signaling by Glutamate
68	GLS+SLC1A6-GRIN1+GRIN2D	-	Ligand-Receptor	Signaling by Glutamate
69	GLS+SLC1A6-GRM1	- GRM1_HUMAN	Ligand-Receptor	Signaling by Glutamate
70	GLS+SLC1A6-GRM2	- GRM2_HUMAN	Ligand-Receptor	Signaling by Glutamate
71	GLS+SLC1A6-GRM3	- GRM3_HUMAN	Ligand-Receptor	Signaling by Glutamate
72	GLS+SLC1A6-GRM5	- GRM5_HUMAN	Ligand-Receptor	Signaling by Glutamate
73	LRFN4-PTPRD	LRFN4_HUMAN - PTPRD_HUMAN	Ligand-Receptor	Signaling by Leucine Rich Repeat And Fibronectin
74	LRFN4-PTPRS	LRFN4_HUMAN - PTPRS_HUMAN	Ligand-Receptor	Signaling by Leucine Rich Repeat And Fibronectin
75	LRFN5-PTPRD	LRFN5_HUMAN - PTPRD_HUMAN	Ligand-Receptor	Signaling by Leucine Rich Repeat And Fibronectin
76	LRFN5-PTPRS	LRFN5_HUMAN - PTPRS_HUMAN	Ligand-Receptor	Signaling by Leucine Rich Repeat And Fibronectin
77	LRRC4B-PTPRD	LRC4B_HUMAN - PTPRD_HUMAN	Ligand-Receptor	Signaling by Leucine Rich Repeat And Fibronectin
78	LRRC4B-PTPRS	LRC4B_HUMAN - PTPRS_HUMAN	Ligand-Receptor	Signaling by Leucine Rich Repeat And Fibronectin
79	LRRTM1-NRXN2	LRRT1_HUMAN - NRX2B_HUMAN	Ligand-Receptor	Signaling by Leucine-Rich Repeat Transmembrane Neuronal Protein
80	LRRTM2-NRXN2	LRRT2_HUMAN - NRX2B_HUMAN	Ligand-Receptor	Signaling by Leucine-Rich Repeat Transmembrane Neuronal Protein
81	LRRTM3-NRXN2	LRRT3_HUMAN - NRX2B_HUMAN	Ligand-Receptor	Signaling by Leucine-Rich Repeat Transmembrane Neuronal Protein
82	NLGN1-NRXN2	NLGN1_HUMAN - NRX2B_HUMAN	Ligand-Receptor	Signaling by Neuroligin
83	NLGN4X-NRXN2	NLGNX_HUMAN - NRX2B_HUMAN	Ligand-Receptor	Signaling by Neuroligin
84	NRG1-ERBB4	NRG1_HUMAN - ERBB4_HUMAN	Ligand-Receptor	Signaling by Neuregulin
85	NRG3-ERBB4	NRG3_HUMAN - ERBB4_HUMAN	Ligand-Receptor	Signaling by Neuregulin
86	NRXN2-DAG1	NRX2B_HUMAN - DAG1_HUMAN	Receptor-Receptor	Signaling by Neurexin
87	PLG-ITGA2B+ITGB3	PLMN_HUMAN -	Ligand-Receptor
88	PTPRD-IL1RAP	PTPRD_HUMAN - IL1AP_HUMAN	Ligand-Receptor
89	PTPRD-IL1RAPL1	PTPRD_HUMAN - IRPL1_HUMAN	Ligand-Receptor
90	SEMA3A-NRP1	SEM3A_HUMAN - NRP1_HUMAN	Ligand-Receptor	Signaling by Semaphorin
91	SEMA3A-NRP1+PLXNA1	SEM3A_HUMAN -	Ligand-Receptor	Signaling by Semaphorin
92	SEMA3A-NRP1+PLXNA2	SEM3A_HUMAN -	Ligand-Receptor	Signaling by Semaphorin
93	SEMA3A-NRP1+PLXNA3	SEM3A_HUMAN -	Ligand-Receptor	Signaling by Semaphorin
94	SEMA3A-NRP1+PLXNA4	SEM3A_HUMAN -	Ligand-Receptor	Signaling by Semaphorin
95	SEMA3F-NRP2	SEM3F_HUMAN - NRP2_HUMAN	Ligand-Receptor	Signaling by Semaphorin
96	SLITRK1-PTPRD	SLIK1_HUMAN - PTPRD_HUMAN	Ligand-Receptor	Signaling by SLIT and NTRK-like protein
97	SLITRK1-PTPRS	SLIK1_HUMAN - PTPRS_HUMAN	Ligand-Receptor	Signaling by SLIT and NTRK-like protein
98	SLITRK2-PTPRD	SLIK2_HUMAN - PTPRD_HUMAN	Ligand-Receptor	Signaling by SLIT and NTRK-like protein
99	SLITRK2-PTPRS	SLIK2_HUMAN - PTPRS_HUMAN	Ligand-Receptor	Signaling by SLIT and NTRK-like protein
100	SLITRK4-PTPRS	SLIK4_HUMAN - PTPRS_HUMAN	Ligand-Receptor	Signaling by SLIT and NTRK-like protein
101	WNT3A-FZD4+LRP5	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
102	WNT3A-FZD4+LRP6	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
103	WNT3A-FZD9+LRP5	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
104	WNT3A-FZD9+LRP6	WNT3A_HUMAN -	Ligand-Receptor	Signaling by WNT
105	WNT5A-FZD4+LRP5	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
106	WNT5A-FZD4+LRP6	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
107	WNT5A-FZD9+LRP5	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
108	WNT5A-FZD9+LRP6	WNT5A_HUMAN -	Ligand-Receptor	Signaling by WNT
109	WNT5A-ROR2	WNT5A_HUMAN - ROR2_HUMAN	Ligand-Receptor	Signaling by WNT
110	WNT7A-FZD4+LRP5	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
111	WNT7A-FZD4+LRP6	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
112	WNT7A-FZD9+LRP5	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT
113	WNT7A-FZD9+LRP6	WNT7A_HUMAN -	Ligand-Receptor	Signaling by WNT

Name	glutamatergic synapse
ID	GO_0098978
collection_id	Cellular component
Description	A synapse that uses glutamate as a neurotransmitter.
External URL
Genes	GRM3 KCNA3 ITGA8 AKAP9 PRSS12 EPHA4 KLHL17 USP6 CRIPT LRRTM2 SNX27 SHANK1 CDKL5 PTPRS KPNA1 DOCK1 STAU1 KCNJ2 SCN8A TIAM1 SYT4 SLC1A6 BTBD9 LZTS1 gluk1-gluk2-gluk3-gluk4_human DNM1 PTPRT SCN2A CAMKV ADCY1 SRC MAPK3 NTNG2 PRKCZ ADAM10 PPP2R2A ADORA2B CDC42 DGKI DOC2A RAB8A OSBPL2 CACNG3 DLGAP2 SPTB PAK3 SLITRK2 BCAN NRCAM GUCY1B1 NUMB PPFIA3 ERBB4 PSEN1 CTTNBP2 NETO1 TAMALIN DROSHA AURKA gluk2-gluk3_human-1 TSPOAP1 PPP2R1A LRFN5 EIF4E SYT1 CHMP2B LIN7C CLSTN2 EPHB1 EGLN1 FBXO2 gluk1-gluk2-gluk5_human DNM3 GRIPAP1 MECP2 PLEKHA5 FLOT1 JAK2 FBXL20 OGT RGS7BP DOCK10 PARN CACNG4 ARHGAP22 NPTX1 ITPKA STX3 GABBR1 C1QL3 PCLO SYT10 DLG5 STXBP1 SRGAP2B SYN2 SEMA4B EPS8 ARF4 gluk1-gluk2-gluk3-gluk5_human LAMA5 NGDN HTR2A ATP2B4 GPC4 CDH11 SYT17 FLNA SLC1A2 ERC2 GABRR1 PLCG1 DAG1 CUL3 PTPRD HCN1 FARP1 GRM5 GRIP2 CSPG5 ADORA2A TNIK RPL22 RAP1B FLRT3 SHANK2 HOMER2 EEA1 GRIA1 PCDH8 P2RX1 PRKCI SV2A RAB17 CDH8 gluk1-gluk3-gluk5_human RGS14 ABTB3 DLG1 PHB2 ADCY8 SRGAP2C YWHAZ USP8 CALB1 KCNJ8 SORCS3 P2RX6 CNR1 ITGA5 NOS1AP PPP1CC gluk1-gluk4_human ELAVL1 gluk2_human-1 ITGB3 APOE ARHGAP44 ASAP1 CBLN1 CPT1C AKT1 CACNG7 PAFAH1B1 ACTB CORO1A PORCN DAPK1 RTN4 RGS9 ACTN1 RPS6KB1 SPTBN2 APPL1 LRFN3 PPM1H PFN2 DRD1 gluk1-gluk2_human-1 GPM6A PFN1 VPS35 PTK2B DLGAP4 EFNB1 CLSTN3 DBNL STK38L gluk3_human ELAVL4 HIP1R VCP WASF3 SPARCL1 SNAP25 KCNA2 RHOA ABLIM3 PLG RAP1A VGF NRG3 NTNG1 GUCY1A1 gluk1-gluk3_human-1 DYNLL2 LRFN4 EPS15 gluk1-gluk5_human PCDH17 RNF10 CHRM1 GSG1L DLGAP1 P2RY1 PPP3CC GRID1 DRD4 gluk3-gluk5_human DTNBP1 P2RY4 CADPS MAPK14 DISC1 NRG1 FXR1 gluk2-gluk5_human SEMA3F SH3GL2 GIPC1 PPP3CA ARHGEF15 SLITRK1 PRRT2 ARPC2 PLPPR4 ATP2B1 PRKAR1B LRRTM1 CHRM2 CNKSR2 PPP1CA PIN1 PLXND1 DLG4 CTNND1 SLC6A17 GSK3B ROR2 VPS18 GRIN2A SHISA9 ARHGAP39 SYN3 TNR STK38 ARRB2 AP3D1 abeta-42-oligomer_human ARF6 RTN4R FZD9 ZDHHC5 HPCA ATAD1 WNT7A ACTBL2 CPLX2 CDH6 CACNG2 DGKE ERBIN gluk3-gluk4_human STX4 RAB11A CACNB4 GRM1 LRRC4 KCND2 ABHD17A HSPA8 GRIK3 CDH10 SEPTIN11 SLITRK4 BAIAP2 LRRC4B DVL1 ICAM5 LYN DGKZ NRP2 GRID2 IL1RAPL2 HIP1 MAL2 PLCB1 LRRK2 PTPRO CLSTN1 CADPS2 LPAR2 LGI1 NRP1 PRKAR1A LRRTM3 SRCIN1 PLAT ADGRA1 CNTNAP1 DNAJB1 EFNB3 FILIP1 SLC16A7 ARFGEF2 DRD2 SLC30A3 CTBP1 GHSR NSG1 TRIO CPSF2 CDH1 PAK2 AGO2 OPHN1 BIN1 CACNG5 GRIN2D HRAS DLGAP3 HNRNPD GPC6 PPFIA2 EFNB2 ACTN2 SNX6 MAP1LC3A NAPA PACSIN2 AP2M1 NRXN2 RNF19A gluk1-gluk3-gluk4_human-1 SLC4A8 ADRA2A DBN1 nlgn1+a+b-nrxn1beta-ss4_human WASL ADAM23 FXYD6 HOMER3 RAC3 SEMA4F NAPB ATP2B2 IL1RAPL1 RHOG HOMER1 FLOT2 BSN PPP3R1 SYNGAP1 GRIK2 CALY EPHB2 LIMK1 LRRC4C gluk1-gluk1_human-1 LPAR1 RELA CLASP2 PURA GRM2 SHISA7 BCR NETO2 IL1RAP ARPC5L NLGN1 ITGA3 UBE3A PRKAR2B GRIN2C SCRIB GHRL NPTXR SEMA3A FZD4 EIF4A3 SH3GL3 TANC1 PPP3CB KCNA1 DLG3 ATP2B3 DRP2 NLGN4X DGCR8 WNT5A ABHD6 ACTC1 ARC ADGRL3 PSD2 CBLN2 FBXO45 WNT3A ASIC1 NF1 KCNJ11 ABR CLCN3 SH3GL1 EPHA7 ABHD17C PRR7 SCN10A NPTX2 SPTBN1 CTNNB1 DGKQ gluk1-gluk2-gluk4_human EEF2K GRIN3A PRKACA FAM81A gluk2-gluk4_human APBA1 CPLX1 RAC1 AP2B1

glutamatergic synapse

I. Involved cell-cell interactions

II. Literature review