Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 18 studies | 31% ± 11% | |
| astrocyte | 17 studies | 33% ± 11% | |
| endothelial cell | 15 studies | 31% ± 15% | |
| basal cell | 14 studies | 37% ± 17% | |
| oligodendrocyte precursor cell | 14 studies | 41% ± 18% | |
| glutamatergic neuron | 12 studies | 59% ± 21% | |
| oligodendrocyte | 11 studies | 26% ± 7% | |
| GABAergic neuron | 10 studies | 49% ± 20% | |
| retinal cone cell | 9 studies | 55% ± 16% | |
| fibroblast | 9 studies | 21% ± 5% | |
| epithelial cell | 8 studies | 39% ± 16% | |
| retinal rod cell | 8 studies | 32% ± 9% | |
| macrophage | 7 studies | 22% ± 5% | |
| neuron | 7 studies | 42% ± 17% | |
| pericyte | 7 studies | 21% ± 3% | |
| goblet cell | 7 studies | 33% ± 18% | |
| amacrine cell | 7 studies | 39% ± 12% | |
| interneuron | 7 studies | 48% ± 23% | |
| microglial cell | 7 studies | 28% ± 4% | |
| club cell | 5 studies | 21% ± 4% | |
| respiratory goblet cell | 5 studies | 24% ± 6% | |
| retinal ganglion cell | 5 studies | 67% ± 25% | |
| retina horizontal cell | 5 studies | 42% ± 11% | |
| Mueller cell | 5 studies | 32% ± 9% | |
| secretory cell | 4 studies | 33% ± 4% | |
| abnormal cell | 4 studies | 24% ± 8% | |
| retinal bipolar neuron | 4 studies | 43% ± 7% | |
| granule cell | 4 studies | 39% ± 12% | |
| OFF-bipolar cell | 4 studies | 39% ± 16% | |
| GABAergic interneuron | 3 studies | 43% ± 10% | |
| kidney loop of Henle epithelial cell | 3 studies | 24% ± 5% | |
| lymphocyte | 3 studies | 21% ± 1% | |
| smooth muscle cell | 3 studies | 16% ± 1% | |
| ON-bipolar cell | 3 studies | 53% ± 8% | |
| rod bipolar cell | 3 studies | 55% ± 3% | |
| type I pneumocyte | 3 studies | 21% ± 2% | |
| dendritic cell | 3 studies | 21% ± 5% | |
| ependymal cell | 3 studies | 43% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 14235.20 | 245 / 245 | 100% | 308.17 | 502 / 502 |
| esophagus | 100% | 10509.26 | 1444 / 1445 | 100% | 293.95 | 183 / 183 |
| brain | 100% | 29460.38 | 2640 / 2642 | 100% | 321.66 | 703 / 705 |
| skin | 100% | 16078.26 | 1808 / 1809 | 100% | 207.47 | 470 / 472 |
| thymus | 100% | 10482.29 | 652 / 653 | 99% | 189.87 | 601 / 605 |
| uterus | 100% | 21047.34 | 170 / 170 | 99% | 230.59 | 455 / 459 |
| ovary | 100% | 15777.78 | 180 / 180 | 99% | 199.06 | 426 / 430 |
| breast | 100% | 8997.20 | 458 / 459 | 99% | 184.35 | 1109 / 1118 |
| intestine | 100% | 11784.82 | 966 / 966 | 99% | 178.15 | 520 / 527 |
| lung | 99% | 7947.30 | 574 / 578 | 99% | 217.83 | 1142 / 1155 |
| pancreas | 100% | 7290.38 | 327 / 328 | 98% | 188.23 | 175 / 178 |
| stomach | 98% | 6264.48 | 351 / 359 | 100% | 169.74 | 285 / 286 |
| kidney | 100% | 10136.00 | 89 / 89 | 97% | 173.28 | 876 / 901 |
| bladder | 100% | 10088.48 | 21 / 21 | 97% | 166.39 | 490 / 504 |
| adrenal gland | 99% | 7151.28 | 256 / 258 | 83% | 151.62 | 191 / 230 |
| eye | 0% | 0 | 0 / 0 | 100% | 211.81 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 91.58 | 29 / 29 |
| spleen | 100% | 6966.59 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 328.62 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 66.55 | 1 / 1 |
| blood vessel | 100% | 11047.87 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 99% | 7189.54 | 1195 / 1204 | 0% | 0 | 0 / 0 |
| heart | 98% | 6480.15 | 842 / 861 | 0% | 0 | 0 / 0 |
| muscle | 78% | 2830.20 | 623 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 40% | 2219.02 | 376 / 929 | 0% | 0 | 0 / 0 |
| liver | 5% | 162.13 | 12 / 226 | 31% | 25.07 | 126 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0001558 | Biological process | regulation of cell growth |
| GO_0007155 | Biological process | cell adhesion |
| GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO_0099003 | Biological process | vesicle-mediated transport in synapse |
| GO_0050806 | Biological process | positive regulation of synaptic transmission |
| GO_0098969 | Biological process | neurotransmitter receptor transport to postsynaptic membrane |
| GO_0051965 | Biological process | positive regulation of synapse assembly |
| GO_0090128 | Biological process | regulation of synapse maturation |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0043005 | Cellular component | neuron projection |
| GO_0009986 | Cellular component | cell surface |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0014069 | Cellular component | postsynaptic density |
| GO_0045211 | Cellular component | postsynaptic membrane |
| GO_0098845 | Cellular component | postsynaptic endosome |
| GO_0005634 | Cellular component | nucleus |
| GO_0001540 | Molecular function | amyloid-beta binding |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0019894 | Molecular function | kinesin binding |
| GO_0042988 | Molecular function | X11-like protein binding |
| Gene name | CLSTN1 |
| Protein name | Calsyntenin-1 (Alcadein-alpha) (Alc-alpha) (Alzheimer-related cadherin-like protein) (Non-classical cadherin XB31alpha) [Cleaved into: Soluble Alc-alpha (SAlc-alpha); CTF1-alpha (C-terminal fragment 1-alpha)] Calsyntenin 1 |
| Synonyms | KIAA0911 CS1 |
| Description | FUNCTION: Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation (By similarity). Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with neurexin-alpha at the presynaptic membrane (By similarity). Also functions as a cargo in axonal anterograde transport by acting as a molecular adapter that promotes KLC1 association with vesicles . Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation . .; FUNCTION: [Soluble Alc-alpha]: As intracellular fragment AlcICD, suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding . .; FUNCTION: [CTF1-alpha]: In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP . . |
| Accessions | ENST00000361311.4 [O94985-2] A0A3B3ITY6 ENST00000377298.9 [O94985-1] Q5SR54 O94985 ENST00000435891.5 ENST00000650348.1 |