Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 18 studies | 31% ± 11% | |
astrocyte | 17 studies | 33% ± 11% | |
endothelial cell | 15 studies | 31% ± 15% | |
basal cell | 14 studies | 37% ± 17% | |
oligodendrocyte precursor cell | 14 studies | 41% ± 18% | |
glutamatergic neuron | 12 studies | 59% ± 21% | |
oligodendrocyte | 11 studies | 26% ± 7% | |
GABAergic neuron | 10 studies | 49% ± 20% | |
retinal cone cell | 9 studies | 55% ± 16% | |
fibroblast | 9 studies | 21% ± 5% | |
epithelial cell | 8 studies | 39% ± 16% | |
retinal rod cell | 8 studies | 32% ± 9% | |
macrophage | 7 studies | 22% ± 5% | |
neuron | 7 studies | 42% ± 17% | |
pericyte | 7 studies | 21% ± 3% | |
goblet cell | 7 studies | 33% ± 18% | |
amacrine cell | 7 studies | 39% ± 12% | |
interneuron | 7 studies | 48% ± 23% | |
microglial cell | 7 studies | 28% ± 4% | |
club cell | 5 studies | 21% ± 4% | |
respiratory goblet cell | 5 studies | 24% ± 6% | |
retinal ganglion cell | 5 studies | 67% ± 25% | |
retina horizontal cell | 5 studies | 42% ± 11% | |
Mueller cell | 5 studies | 32% ± 9% | |
secretory cell | 4 studies | 33% ± 4% | |
abnormal cell | 4 studies | 24% ± 8% | |
retinal bipolar neuron | 4 studies | 43% ± 7% | |
granule cell | 4 studies | 39% ± 12% | |
OFF-bipolar cell | 4 studies | 39% ± 16% | |
GABAergic interneuron | 3 studies | 43% ± 10% | |
kidney loop of Henle epithelial cell | 3 studies | 24% ± 5% | |
lymphocyte | 3 studies | 21% ± 1% | |
smooth muscle cell | 3 studies | 16% ± 1% | |
ON-bipolar cell | 3 studies | 53% ± 8% | |
rod bipolar cell | 3 studies | 55% ± 3% | |
type I pneumocyte | 3 studies | 21% ± 2% | |
dendritic cell | 3 studies | 21% ± 5% | |
ependymal cell | 3 studies | 43% ± 13% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 14235.20 | 245 / 245 | 100% | 308.17 | 502 / 502 |
esophagus | 100% | 10509.26 | 1444 / 1445 | 100% | 293.95 | 183 / 183 |
brain | 100% | 29460.38 | 2640 / 2642 | 100% | 321.66 | 703 / 705 |
skin | 100% | 16078.26 | 1808 / 1809 | 100% | 207.47 | 470 / 472 |
thymus | 100% | 10482.29 | 652 / 653 | 99% | 189.87 | 601 / 605 |
uterus | 100% | 21047.34 | 170 / 170 | 99% | 230.59 | 455 / 459 |
ovary | 100% | 15777.78 | 180 / 180 | 99% | 199.06 | 426 / 430 |
breast | 100% | 8997.20 | 458 / 459 | 99% | 184.35 | 1109 / 1118 |
intestine | 100% | 11784.82 | 966 / 966 | 99% | 178.15 | 520 / 527 |
lung | 99% | 7947.30 | 574 / 578 | 99% | 217.83 | 1142 / 1155 |
pancreas | 100% | 7290.38 | 327 / 328 | 98% | 188.23 | 175 / 178 |
stomach | 98% | 6264.48 | 351 / 359 | 100% | 169.74 | 285 / 286 |
kidney | 100% | 10136.00 | 89 / 89 | 97% | 173.28 | 876 / 901 |
bladder | 100% | 10088.48 | 21 / 21 | 97% | 166.39 | 490 / 504 |
adrenal gland | 99% | 7151.28 | 256 / 258 | 83% | 151.62 | 191 / 230 |
eye | 0% | 0 | 0 / 0 | 100% | 211.81 | 80 / 80 |
lymph node | 0% | 0 | 0 / 0 | 100% | 91.58 | 29 / 29 |
spleen | 100% | 6966.59 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 328.62 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 66.55 | 1 / 1 |
blood vessel | 100% | 11047.87 | 1333 / 1335 | 0% | 0 | 0 / 0 |
adipose | 99% | 7189.54 | 1195 / 1204 | 0% | 0 | 0 / 0 |
heart | 98% | 6480.15 | 842 / 861 | 0% | 0 | 0 / 0 |
muscle | 78% | 2830.20 | 623 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 40% | 2219.02 | 376 / 929 | 0% | 0 | 0 / 0 |
liver | 5% | 162.13 | 12 / 226 | 31% | 25.07 | 126 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0001558 | Biological process | regulation of cell growth |
GO_0007155 | Biological process | cell adhesion |
GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
GO_0099003 | Biological process | vesicle-mediated transport in synapse |
GO_0050806 | Biological process | positive regulation of synaptic transmission |
GO_0098969 | Biological process | neurotransmitter receptor transport to postsynaptic membrane |
GO_0051965 | Biological process | positive regulation of synapse assembly |
GO_0090128 | Biological process | regulation of synapse maturation |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005576 | Cellular component | extracellular region |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0043005 | Cellular component | neuron projection |
GO_0009986 | Cellular component | cell surface |
GO_0000139 | Cellular component | Golgi membrane |
GO_0014069 | Cellular component | postsynaptic density |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0098845 | Cellular component | postsynaptic endosome |
GO_0005634 | Cellular component | nucleus |
GO_0001540 | Molecular function | amyloid-beta binding |
GO_0005509 | Molecular function | calcium ion binding |
GO_0005515 | Molecular function | protein binding |
GO_0019894 | Molecular function | kinesin binding |
GO_0042988 | Molecular function | X11-like protein binding |
Gene name | CLSTN1 |
Protein name | Calsyntenin-1 (Alcadein-alpha) (Alc-alpha) (Alzheimer-related cadherin-like protein) (Non-classical cadherin XB31alpha) [Cleaved into: Soluble Alc-alpha (SAlc-alpha); CTF1-alpha (C-terminal fragment 1-alpha)] Calsyntenin 1 |
Synonyms | KIAA0911 CS1 |
Description | FUNCTION: Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation (By similarity). Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with neurexin-alpha at the presynaptic membrane (By similarity). Also functions as a cargo in axonal anterograde transport by acting as a molecular adapter that promotes KLC1 association with vesicles . Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation . .; FUNCTION: [Soluble Alc-alpha]: As intracellular fragment AlcICD, suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding . .; FUNCTION: [CTF1-alpha]: In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP . . |
Accessions | ENST00000361311.4 [O94985-2] A0A3B3ITY6 ENST00000377298.9 [O94985-1] Q5SR54 O94985 ENST00000435891.5 ENST00000650348.1 |