Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| glutamatergic neuron | 12 studies | 68% ± 22% | |
| GABAergic neuron | 7 studies | 48% ± 20% | |
| neuron | 6 studies | 29% ± 13% | |
| astrocyte | 6 studies | 33% ± 16% | |
| interneuron | 6 studies | 49% ± 19% | |
| retinal ganglion cell | 6 studies | 63% ± 30% | |
| retinal cone cell | 6 studies | 55% ± 17% | |
| OFF-bipolar cell | 5 studies | 46% ± 26% | |
| retinal bipolar neuron | 4 studies | 35% ± 11% | |
| granule cell | 4 studies | 74% ± 7% | |
| oligodendrocyte precursor cell | 4 studies | 22% ± 4% | |
| amacrine cell | 4 studies | 40% ± 13% | |
| ON-bipolar cell | 4 studies | 51% ± 23% | |
| retinal rod cell | 4 studies | 27% ± 7% | |
| GABAergic interneuron | 3 studies | 32% ± 11% | |
| rod bipolar cell | 3 studies | 45% ± 16% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 97% | 9822.52 | 2571 / 2642 | 97% | 102.52 | 686 / 705 |
| kidney | 81% | 787.63 | 72 / 89 | 42% | 6.45 | 375 / 901 |
| prostate | 12% | 102.31 | 29 / 245 | 66% | 4.81 | 333 / 502 |
| stomach | 66% | 695.13 | 237 / 359 | 5% | 0.48 | 14 / 286 |
| bladder | 33% | 420.05 | 7 / 21 | 19% | 3.61 | 95 / 504 |
| pancreas | 1% | 5.27 | 3 / 328 | 44% | 4.52 | 78 / 178 |
| skin | 0% | 0.61 | 2 / 1809 | 29% | 3.78 | 138 / 472 |
| esophagus | 21% | 134.45 | 304 / 1445 | 7% | 0.41 | 12 / 183 |
| uterus | 8% | 51.41 | 14 / 170 | 16% | 2.07 | 74 / 459 |
| thymus | 3% | 17.02 | 20 / 653 | 20% | 2.24 | 124 / 605 |
| eye | 0% | 0 | 0 / 0 | 18% | 1.67 | 14 / 80 |
| ovary | 4% | 21.52 | 7 / 180 | 12% | 0.74 | 51 / 430 |
| adrenal gland | 1% | 16.93 | 2 / 258 | 13% | 1.37 | 29 / 230 |
| breast | 0% | 0 | 0 / 459 | 12% | 0.87 | 138 / 1118 |
| heart | 10% | 69.68 | 90 / 861 | 0% | 0 | 0 / 0 |
| lung | 2% | 11.86 | 14 / 578 | 6% | 0.62 | 69 / 1155 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.75 | 3 / 45 |
| intestine | 0% | 0.51 | 1 / 966 | 6% | 0.58 | 33 / 527 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 1.90 | 1 / 29 |
| liver | 0% | 0 | 0 / 226 | 2% | 0.08 | 10 / 406 |
| adipose | 0% | 1.22 | 3 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.85 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0016191 | Biological process | synaptic vesicle uncoating |
| GO_0010629 | Biological process | negative regulation of gene expression |
| GO_1990416 | Biological process | cellular response to brain-derived neurotrophic factor stimulus |
| GO_0097484 | Biological process | dendrite extension |
| GO_0031175 | Biological process | neuron projection development |
| GO_0007165 | Biological process | signal transduction |
| GO_1905604 | Biological process | negative regulation of blood-brain barrier permeability |
| GO_0001933 | Biological process | negative regulation of protein phosphorylation |
| GO_0007417 | Biological process | central nervous system development |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0098793 | Cellular component | presynapse |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0048471 | Cellular component | perinuclear region of cytoplasm |
| GO_0005769 | Cellular component | early endosome |
| GO_0030669 | Cellular component | clathrin-coated endocytic vesicle membrane |
| GO_0000139 | Cellular component | Golgi membrane |
| GO_0005829 | Cellular component | cytosol |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0042995 | Cellular component | cell projection |
| GO_0008289 | Molecular function | lipid binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | SH3GL2 |
| Protein name | Endophilin Endophilin A1 BAR domain Mutated endophilin A1 BAR domain Endophilin-A1 (EEN-B1) (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) SH3GL2 protein |
| Synonyms | CNSA2 SH3D2A |
| Description | FUNCTION: Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes. . |
| Accessions | Q8IZ09 ENST00000380607.5 A7LBA6 Q3V639 Q3V638 Q99962 |