ADORA2B | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	3 studies	23% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADORA2B at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	89%	362.82	860 / 966	92%	21.01	487 / 527
lung	83%	177.19	481 / 578	91%	16.32	1054 / 1155
brain	94%	373.83	2480 / 2642	79%	6.85	555 / 705
bladder	86%	195.52	18 / 21	84%	17.02	425 / 504
skin	100%	610.24	1807 / 1809	67%	7.60	314 / 472
esophagus	55%	282.32	793 / 1445	89%	18.80	163 / 183
pancreas	39%	38.53	127 / 328	89%	11.31	159 / 178
uterus	39%	70.98	67 / 170	87%	16.22	398 / 459
stomach	31%	42.68	110 / 359	75%	14.17	214 / 286
prostate	78%	157.72	190 / 245	26%	1.39	133 / 502
tonsil	0%	0	0 / 0	98%	25.65	44 / 45
breast	47%	68.07	216 / 459	50%	3.81	555 / 1118
adrenal gland	79%	119.08	203 / 258	17%	1.47	40 / 230
heart	45%	49.98	387 / 861	0%	0	0 / 0
kidney	12%	11.98	11 / 89	31%	1.81	282 / 901
ovary	27%	25.49	48 / 180	14%	0.80	62 / 430
peripheral blood	35%	41.37	322 / 929	0%	0	0 / 0
adipose	33%	37.62	395 / 1204	0%	0	0 / 0
thymus	12%	10.78	80 / 653	18%	1.38	110 / 605
spleen	23%	19.02	55 / 241	0%	0	0 / 0
liver	2%	1.85	5 / 226	14%	1.40	58 / 406
eye	0%	0	0 / 0	16%	0.76	13 / 80
blood vessel	11%	9.73	145 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	3%	0.12	1 / 29
muscle	3%	2.48	25 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0043306	Biological process	positive regulation of mast cell degranulation
GO_0019934	Biological process	cGMP-mediated signaling
GO_0032722	Biological process	positive regulation of chemokine production
GO_0001973	Biological process	G protein-coupled adenosine receptor signaling pathway
GO_0060087	Biological process	relaxation of vascular associated smooth muscle
GO_0002882	Biological process	positive regulation of chronic inflammatory response to non-antigenic stimulus
GO_0043303	Biological process	mast cell degranulation
GO_0007190	Biological process	activation of adenylate cyclase activity
GO_0007186	Biological process	G protein-coupled receptor signaling pathway
GO_0099171	Biological process	presynaptic modulation of chemical synaptic transmission
GO_0010575	Biological process	positive regulation of vascular endothelial growth factor production
GO_0007189	Biological process	adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0010753	Biological process	positive regulation of cGMP-mediated signaling
GO_0042311	Biological process	vasodilation
GO_0032755	Biological process	positive regulation of interleukin-6 production
GO_0098978	Cellular component	glutamatergic synapse
GO_0098793	Cellular component	presynapse
GO_0098685	Cellular component	Schaffer collateral - CA1 synapse
GO_0005886	Cellular component	plasma membrane
GO_0004930	Molecular function	G protein-coupled receptor activity
GO_0001609	Molecular function	G protein-coupled adenosine receptor activity
GO_0005515	Molecular function	protein binding

Gene name	ADORA2B
Protein name	Adenosine receptor A2b Adenosine A2b receptor
Synonyms
Description	FUNCTION: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Accessions	A0MCH9 P29275 Q2L7J7 ENST00000304222.3

ADORA2B report