relaxation of vascular associated smooth muscle

I. Literature review

[source]
Namerelaxation of vascular associated smooth muscle
IDGO_0060087
collection_id

Biological process

Alternative ID

GO:1905657, GO:1905658, GO:1905659

Exact synonym

relaxation of vascular smooth muscle, vascular smooth muscle relaxation

Description

A negative regulation of smooth muscle contraction resulting in relaxation of vascular smooth muscle. The relaxation is mediated by a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.

Related synonym

negative regulation of relaxation of vascular smooth muscle, positive regulation of relaxation of vascular smooth muscle, regulation of relaxation of vascular smooth muscle

External URL
Genes