Name | Number of supported studies | Average coverage | |
---|---|---|---|
pericyte | 30 studies | 37% ± 12% | |
smooth muscle cell | 22 studies | 36% ± 12% | |
fibroblast | 19 studies | 28% ± 12% | |
myofibroblast cell | 5 studies | 29% ± 11% | |
retinal bipolar neuron | 5 studies | 36% ± 12% | |
endothelial cell | 5 studies | 27% ± 10% | |
endothelial cell of lymphatic vessel | 5 studies | 26% ± 9% | |
GABAergic neuron | 5 studies | 37% ± 17% | |
hematopoietic stem cell | 5 studies | 23% ± 8% | |
interneuron | 5 studies | 24% ± 7% | |
OFF-bipolar cell | 4 studies | 29% ± 11% | |
type II pneumocyte | 4 studies | 25% ± 6% | |
glutamatergic neuron | 4 studies | 49% ± 18% | |
connective tissue cell | 4 studies | 32% ± 10% | |
neuron | 3 studies | 20% ± 3% | |
epithelial cell | 3 studies | 24% ± 4% | |
ON-bipolar cell | 3 studies | 22% ± 5% | |
rod bipolar cell | 3 studies | 67% ± 3% | |
endothelial cell of artery | 3 studies | 24% ± 6% | |
microglial cell | 3 studies | 20% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 99% | 2927.40 | 243 / 245 | 100% | 54.33 | 501 / 502 |
breast | 98% | 1964.24 | 451 / 459 | 91% | 15.43 | 1016 / 1118 |
lung | 100% | 2070.93 | 578 / 578 | 88% | 10.83 | 1014 / 1155 |
kidney | 96% | 1153.83 | 85 / 89 | 89% | 26.12 | 806 / 901 |
pancreas | 90% | 640.30 | 294 / 328 | 87% | 10.25 | 154 / 178 |
thymus | 98% | 1260.52 | 638 / 653 | 73% | 5.23 | 439 / 605 |
esophagus | 76% | 1863.10 | 1099 / 1445 | 74% | 8.46 | 135 / 183 |
brain | 71% | 747.60 | 1882 / 2642 | 72% | 7.46 | 509 / 705 |
intestine | 88% | 3843.64 | 851 / 966 | 55% | 5.20 | 288 / 527 |
uterus | 97% | 1626.06 | 165 / 170 | 33% | 2.43 | 150 / 459 |
stomach | 60% | 1559.52 | 216 / 359 | 69% | 10.19 | 198 / 286 |
adrenal gland | 46% | 279.07 | 118 / 258 | 64% | 11.03 | 147 / 230 |
bladder | 67% | 525.71 | 14 / 21 | 42% | 3.38 | 213 / 504 |
blood vessel | 100% | 3406.45 | 1335 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 1858.19 | 848 / 861 | 0% | 0 | 0 / 0 |
adipose | 98% | 1787.94 | 1180 / 1204 | 0% | 0 | 0 / 0 |
spleen | 94% | 845.00 | 227 / 241 | 0% | 0 | 0 / 0 |
ovary | 46% | 584.56 | 82 / 180 | 31% | 2.02 | 135 / 430 |
liver | 37% | 197.14 | 83 / 226 | 26% | 2.17 | 107 / 406 |
skin | 37% | 274.69 | 664 / 1809 | 24% | 1.46 | 113 / 472 |
tonsil | 0% | 0 | 0 / 0 | 60% | 4.90 | 27 / 45 |
muscle | 45% | 263.10 | 363 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 34% | 1.64 | 10 / 29 |
peripheral blood | 9% | 113.65 | 88 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 4% | 0.15 | 3 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0019934 | Biological process | cGMP-mediated signaling |
GO_0006182 | Biological process | cGMP biosynthetic process |
GO_0038060 | Biological process | nitric oxide-cGMP-mediated signaling |
GO_0008217 | Biological process | regulation of blood pressure |
GO_0060087 | Biological process | relaxation of vascular associated smooth muscle |
GO_0007263 | Biological process | nitric oxide mediated signal transduction |
GO_0098925 | Biological process | retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission |
GO_0008015 | Biological process | blood circulation |
GO_0070482 | Biological process | response to oxygen levels |
GO_0010750 | Biological process | positive regulation of nitric oxide mediated signal transduction |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0098982 | Cellular component | GABA-ergic synapse |
GO_0005829 | Cellular component | cytosol |
GO_0008074 | Cellular component | guanylate cyclase complex, soluble |
GO_0038023 | Molecular function | signaling receptor activity |
GO_0005525 | Molecular function | GTP binding |
GO_0020037 | Molecular function | heme binding |
GO_0004383 | Molecular function | guanylate cyclase activity |
GO_0005515 | Molecular function | protein binding |
Gene name | GUCY1A1 |
Protein name | Guanylate cyclase 1 soluble subunit alpha 1 Guanylate cyclase soluble subunit alpha-1 (GCS-alpha-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit alpha-3) (GCS-alpha-3) (Soluble guanylate cyclase large subunit) Guanylate cyclase soluble subunit alpha-1 (Soluble guanylate cyclase large subunit) GUCY1A3 protein (Guanylate cyclase 1 soluble subunit alpha 1) (Guanylate cyclase 1, soluble, alpha 3, isoform CRA_c) |
Synonyms | GUC1A3 GUCSA3 hCG_28051 GUCY1A3 |
Description | |
Accessions | ENST00000296518.11 [Q02108-1] ENST00000506455.6 [Q02108-1] ENST00000511108.5 [Q02108-1] ENST00000511507.5 [Q02108-2] J3KPQ8 ENST00000513574.1 [Q02108-1] ENST00000509901.5 ENST00000455639.6 [Q02108-1] ENST00000621234.4 ENST00000515201.5 Q02108 D6RF78 ENST00000443668.6 Q6PJR4 J3KQW2 ENST00000393832.7 |