ARF4 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	40 studies	49% ± 20%	Explore
endothelial cell	36 studies	34% ± 14%	Explore
natural killer cell	28 studies	24% ± 7%	Explore
macrophage	28 studies	26% ± 10%	Explore
pericyte	28 studies	37% ± 16%	Explore
smooth muscle cell	25 studies	37% ± 13%	Explore
conventional dendritic cell	22 studies	29% ± 12%	Explore
plasma cell	22 studies	43% ± 22%	Explore
epithelial cell	22 studies	47% ± 21%	Explore
CD4-positive, alpha-beta T cell	22 studies	23% ± 6%	Explore
basal cell	21 studies	43% ± 18%	Explore
B cell	21 studies	21% ± 5%	Explore
CD8-positive, alpha-beta T cell	21 studies	23% ± 6%	Explore
T cell	19 studies	25% ± 8%	Explore
regulatory T cell	19 studies	25% ± 5%	Explore
connective tissue cell	18 studies	54% ± 17%	Explore
plasmacytoid dendritic cell	17 studies	34% ± 12%	Explore
classical monocyte	17 studies	27% ± 9%	Explore
non-classical monocyte	16 studies	25% ± 9%	Explore
monocyte	15 studies	24% ± 7%	Explore
endothelial cell of lymphatic vessel	14 studies	31% ± 11%	Explore
myofibroblast cell	14 studies	47% ± 16%	Explore
ciliated cell	13 studies	42% ± 19%	Explore
gamma-delta T cell	13 studies	27% ± 9%	Explore
capillary endothelial cell	12 studies	29% ± 12%	Explore
vein endothelial cell	12 studies	28% ± 8%	Explore
endothelial cell of vascular tree	12 studies	34% ± 7%	Explore
plasmablast	11 studies	55% ± 20%	Explore
secretory cell	11 studies	49% ± 18%	Explore
endothelial cell of artery	11 studies	32% ± 11%	Explore
goblet cell	11 studies	45% ± 15%	Explore
mesothelial cell	11 studies	48% ± 21%	Explore
memory B cell	11 studies	22% ± 4%	Explore
mast cell	11 studies	22% ± 4%	Explore
type II pneumocyte	10 studies	37% ± 18%	Explore
naive B cell	10 studies	20% ± 5%	Explore
CD16-negative, CD56-bright natural killer cell, human	10 studies	29% ± 9%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	25% ± 7%	Explore
mature NK T cell	10 studies	25% ± 5%	Explore
type I pneumocyte	9 studies	35% ± 14%	Explore
club cell	9 studies	36% ± 15%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	20% ± 2%	Explore
abnormal cell	9 studies	34% ± 14%	Explore
dendritic cell	9 studies	30% ± 16%	Explore
mucosal invariant T cell	9 studies	27% ± 4%	Explore
myeloid cell	9 studies	30% ± 15%	Explore
CD8-positive, alpha-beta memory T cell	8 studies	26% ± 8%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	26% ± 8%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	25% ± 8%	Explore
leukocyte	7 studies	26% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	25% ± 2%	Explore
epithelial cell of proximal tubule	7 studies	24% ± 8%	Explore
progenitor cell	7 studies	43% ± 12%	Explore
IgA plasma cell	7 studies	34% ± 14%	Explore
IgG plasma cell	7 studies	30% ± 12%	Explore
neuron	7 studies	42% ± 20%	Explore
astrocyte	7 studies	26% ± 13%	Explore
respiratory goblet cell	6 studies	37% ± 23%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	19% ± 2%	Explore
mononuclear phagocyte	6 studies	29% ± 14%	Explore
kidney loop of Henle epithelial cell	6 studies	28% ± 4%	Explore
enterocyte	6 studies	31% ± 8%	Explore
innate lymphoid cell	6 studies	32% ± 6%	Explore
T follicular helper cell	6 studies	24% ± 5%	Explore
oligodendrocyte precursor cell	6 studies	30% ± 10%	Explore
hematopoietic precursor cell	5 studies	31% ± 8%	Explore
transit amplifying cell	5 studies	24% ± 7%	Explore
mucus secreting cell	5 studies	36% ± 14%	Explore
erythrocyte	5 studies	33% ± 19%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	26% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	25% ± 5%	Explore
glutamatergic neuron	5 studies	37% ± 12%	Explore
platelet	5 studies	24% ± 8%	Explore
oligodendrocyte	5 studies	18% ± 2%	Explore
duct epithelial cell	4 studies	32% ± 3%	Explore
pancreatic A cell	4 studies	54% ± 21%	Explore
type B pancreatic cell	4 studies	59% ± 26%	Explore
kidney distal convoluted tubule epithelial cell	4 studies	39% ± 7%	Explore
renal alpha-intercalated cell	4 studies	39% ± 11%	Explore
enteroendocrine cell	4 studies	40% ± 16%	Explore
intestinal crypt stem cell	4 studies	24% ± 9%	Explore
hematopoietic stem cell	4 studies	22% ± 3%	Explore
immature B cell	4 studies	23% ± 6%	Explore
microglial cell	4 studies	24% ± 10%	Explore
adventitial cell	4 studies	50% ± 13%	Explore
alveolar macrophage	4 studies	22% ± 2%	Explore
muscle cell	4 studies	34% ± 18%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	62% ± 4%	Explore
granulocyte	4 studies	25% ± 7%	Explore
luminal cell of prostate epithelium	4 studies	39% ± 15%	Explore
GABAergic neuron	4 studies	33% ± 7%	Explore
interneuron	4 studies	30% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	20% ± 4%	Explore
ionocyte	3 studies	27% ± 6%	Explore
precursor cell	3 studies	41% ± 12%	Explore
squamous epithelial cell	3 studies	50% ± 21%	Explore
pancreatic D cell	3 studies	55% ± 26%	Explore
glomerular endothelial cell	3 studies	26% ± 4%	Explore
neural crest cell	3 studies	34% ± 0%	Explore
renal principal cell	3 studies	44% ± 7%	Explore
extravillous trophoblast	3 studies	69% ± 9%	Explore
placental villous trophoblast	3 studies	69% ± 15%	Explore
lymphocyte	3 studies	32% ± 17%	Explore
precursor B cell	3 studies	32% ± 9%	Explore
pro-B cell	3 studies	27% ± 9%	Explore
retinal pigment epithelial cell	3 studies	36% ± 14%	Explore
serous secreting cell	3 studies	37% ± 2%	Explore
Mueller cell	3 studies	40% ± 10%	Explore
acinar cell	3 studies	52% ± 28%	Explore
erythroblast	3 studies	35% ± 25%	Explore
exhausted T cell	3 studies	26% ± 5%	Explore
intermediate monocyte	3 studies	32% ± 12%	Explore
adipocyte	3 studies	30% ± 13%	Explore
myoepithelial cell	3 studies	58% ± 5%	Explore
IgM plasma cell	3 studies	38% ± 8%	Explore
pancreatic ductal cell	3 studies	61% ± 20%	Explore
megakaryocyte	3 studies	39% ± 11%	Explore
glial cell	3 studies	37% ± 22%	Explore
group 3 innate lymphoid cell	3 studies	37% ± 9%	Explore
T-helper 1 cell	3 studies	33% ± 3%	Explore
double negative thymocyte	3 studies	36% ± 13%	Explore
progenitor cell of mammary luminal epithelium	3 studies	48% ± 7%	Explore
hepatocyte	3 studies	48% ± 24%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	18 studies	35% ± 16%	Explore
peripheral blood	12 studies	24% ± 5%	Explore
intestine	12 studies	31% ± 16%	Explore
kidney	9 studies	27% ± 7%	Explore
brain	9 studies	27% ± 10%	Explore
eye	6 studies	28% ± 11%	Explore
liver	6 studies	27% ± 19%	Explore
placenta	5 studies	44% ± 23%	Explore
uterus	5 studies	44% ± 14%	Explore
pancreas	4 studies	57% ± 23%	Explore
bone marrow	4 studies	22% ± 8%	Explore
prostate	4 studies	46% ± 14%	Explore
breast	4 studies	44% ± 4%	Explore
heart	3 studies	21% ± 6%	Explore
esophagus	3 studies	44% ± 26%	Explore
skin	3 studies	39% ± 5%	Explore
thymus	3 studies	36% ± 9%	Explore
lymph node	3 studies	25% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	6642.52	1445 / 1445	100%	221.54	183 / 183
lung	100%	9884.82	578 / 578	100%	297.13	1155 / 1155
ovary	100%	8022.08	180 / 180	100%	303.71	430 / 430
pancreas	100%	6208.42	328 / 328	100%	317.82	178 / 178
breast	100%	7766.31	459 / 459	100%	374.93	1115 / 1118
stomach	100%	6610.15	359 / 359	100%	279.27	285 / 286
skin	100%	9896.19	1806 / 1809	100%	314.85	471 / 472
intestine	100%	7239.61	966 / 966	100%	287.69	525 / 527
prostate	100%	7485.36	244 / 245	100%	345.54	501 / 502
uterus	100%	7425.64	170 / 170	99%	268.88	456 / 459
thymus	100%	8124.76	653 / 653	99%	224.08	599 / 605
bladder	100%	7752.76	21 / 21	99%	264.17	499 / 504
liver	100%	6634.89	226 / 226	99%	172.11	401 / 406
brain	99%	4168.32	2607 / 2642	100%	223.55	705 / 705
adrenal gland	100%	11746.49	258 / 258	98%	217.76	226 / 230
kidney	100%	6041.22	89 / 89	98%	158.71	879 / 901
adipose	100%	8983.22	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	132.14	29 / 29
spleen	100%	5002.16	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	176.74	45 / 45
ureter	0%	0	0 / 0	100%	119.48	1 / 1
blood vessel	100%	9829.23	1334 / 1335	0%	0	0 / 0
muscle	98%	2768.07	788 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	98%	112.03	78 / 80
heart	97%	5154.40	838 / 861	0%	0	0 / 0
peripheral blood	96%	4662.01	895 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0060271	Biological process	cilium assembly
GO_0061512	Biological process	protein localization to cilium
GO_2000377	Biological process	regulation of reactive oxygen species metabolic process
GO_0006890	Biological process	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO_0007612	Biological process	learning
GO_0006886	Biological process	intracellular protein transport
GO_0045176	Biological process	apical protein localization
GO_1902017	Biological process	regulation of cilium assembly
GO_0045197	Biological process	establishment or maintenance of epithelial cell apical/basal polarity
GO_0016192	Biological process	vesicle-mediated transport
GO_0060996	Biological process	dendritic spine development
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0006888	Biological process	endoplasmic reticulum to Golgi vesicle-mediated transport
GO_0016477	Biological process	cell migration
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0099175	Biological process	regulation of postsynapse organization
GO_0032587	Cellular component	ruffle membrane
GO_0098978	Cellular component	glutamatergic synapse
GO_0005886	Cellular component	plasma membrane
GO_0043197	Cellular component	dendritic spine
GO_0016020	Cellular component	membrane
GO_0070062	Cellular component	extracellular exosome
GO_0000139	Cellular component	Golgi membrane
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0005085	Molecular function	guanyl-nucleotide exchange factor activity
GO_0106274	Molecular function	NAD+-protein-arginine ADP-ribosyltransferase activity
GO_0005154	Molecular function	epidermal growth factor receptor binding
GO_0005525	Molecular function	GTP binding
GO_0005515	Molecular function	protein binding
GO_1990583	Molecular function	phospholipase D activator activity
GO_0003924	Molecular function	GTPase activity

IV. Literature review

[source]

Gene name	ARF4
Protein name	ADP-ribosylation factor 4 ADP ribosylation factor 4
Synonyms	ARF2
Description	FUNCTION: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Part of the ciliary targeting complex containing Rab11, ASAP1, Rabin8/RAB3IP, RAB11FIP3 and ARF4, which direct preciliary vesicle trafficking to mother centriole and ciliogenesis initiation . .
Accessions	ENST00000463880.1 C9JAK5 C9JPM4 ENST00000488156.1 F8WDB3 U3KQF2 ENST00000489843.1 ENST00000303436.11 ENST00000486310.5 P18085 ENST00000496292.5 C9J6P1

ARF4 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review