Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 9 studies | 27% ± 13% | |
| cardiac muscle cell | 7 studies | 75% ± 20% | |
| oligodendrocyte precursor cell | 4 studies | 18% ± 3% | |
| GABAergic neuron | 3 studies | 21% ± 2% | |
| glutamatergic neuron | 3 studies | 45% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 69% | 3935.19 | 1818 / 2642 | 100% | 22.76 | 702 / 705 |
| muscle | 100% | 252413.66 | 803 / 803 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 100% | 1.62 | 1 / 1 |
| heart | 99% | 107974.35 | 856 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 62% | 2510.79 | 827 / 1335 | 0% | 0 | 0 / 0 |
| esophagus | 43% | 1813.86 | 623 / 1445 | 9% | 0.39 | 17 / 183 |
| stomach | 23% | 811.34 | 84 / 359 | 12% | 1.00 | 34 / 286 |
| liver | 0% | 0 | 0 / 226 | 34% | 5.16 | 139 / 406 |
| prostate | 10% | 938.93 | 24 / 245 | 24% | 7.86 | 121 / 502 |
| bladder | 24% | 789.29 | 5 / 21 | 8% | 0.27 | 42 / 504 |
| skin | 0% | 103.41 | 9 / 1809 | 31% | 1.07 | 147 / 472 |
| lung | 19% | 538.72 | 112 / 578 | 10% | 0.43 | 110 / 1155 |
| tonsil | 0% | 0 | 0 / 0 | 24% | 8.77 | 11 / 45 |
| adrenal gland | 0% | 13.10 | 1 / 258 | 20% | 1.76 | 47 / 230 |
| breast | 2% | 151.67 | 8 / 459 | 18% | 1.48 | 197 / 1118 |
| kidney | 0% | 0 | 0 / 89 | 19% | 0.81 | 173 / 901 |
| lymph node | 0% | 0 | 0 / 0 | 17% | 0.93 | 5 / 29 |
| uterus | 0% | 0 | 0 / 170 | 14% | 8.08 | 66 / 459 |
| ovary | 0% | 0 | 0 / 180 | 6% | 0.20 | 27 / 430 |
| pancreas | 0% | 4.51 | 1 / 328 | 6% | 0.40 | 10 / 178 |
| intestine | 1% | 17.51 | 7 / 966 | 3% | 0.14 | 16 / 527 |
| eye | 0% | 0 | 0 / 0 | 4% | 0.05 | 3 / 80 |
| thymus | 2% | 91.64 | 10 / 653 | 1% | 0.44 | 7 / 605 |
| peripheral blood | 2% | 100.31 | 17 / 929 | 0% | 0 | 0 / 0 |
| adipose | 1% | 39.89 | 14 / 1204 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| GO_2001259 | Biological process | positive regulation of cation channel activity |
| GO_0072659 | Biological process | protein localization to plasma membrane |
| GO_0042391 | Biological process | regulation of membrane potential |
| GO_0055001 | Biological process | muscle cell development |
| GO_0055013 | Biological process | cardiac muscle cell development |
| GO_1901018 | Biological process | positive regulation of potassium ion transmembrane transporter activity |
| GO_0086097 | Biological process | phospholipase C-activating angiotensin-activated signaling pathway |
| GO_0007155 | Biological process | cell adhesion |
| GO_0030036 | Biological process | actin cytoskeleton organization |
| GO_0051695 | Biological process | actin filament uncapping |
| GO_0042981 | Biological process | regulation of apoptotic process |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0043267 | Biological process | negative regulation of potassium ion transport |
| GO_2000009 | Biological process | negative regulation of protein localization to cell surface |
| GO_0043268 | Biological process | positive regulation of potassium ion transport |
| GO_0048041 | Biological process | focal adhesion assembly |
| GO_0030035 | Biological process | microspike assembly |
| GO_0045214 | Biological process | sarcomere organization |
| GO_1901017 | Biological process | negative regulation of potassium ion transmembrane transporter activity |
| GO_2001137 | Biological process | positive regulation of endocytic recycling |
| GO_0098978 | Cellular component | glutamatergic synapse |
| GO_0098839 | Cellular component | postsynaptic density membrane |
| GO_0005856 | Cellular component | cytoskeleton |
| GO_0005576 | Cellular component | extracellular region |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0043197 | Cellular component | dendritic spine |
| GO_0030018 | Cellular component | Z disc |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0030864 | Cellular component | cortical actin cytoskeleton |
| GO_0005884 | Cellular component | actin filament |
| GO_0005925 | Cellular component | focal adhesion |
| GO_0030175 | Cellular component | filopodium |
| GO_0005829 | Cellular component | cytosol |
| GO_0031093 | Cellular component | platelet alpha granule lumen |
| GO_0098871 | Cellular component | postsynaptic actin cytoskeleton |
| GO_0042995 | Cellular component | cell projection |
| GO_0031143 | Cellular component | pseudopodium |
| GO_0030054 | Cellular component | cell junction |
| GO_0099092 | Cellular component | postsynaptic density, intracellular component |
| GO_0030274 | Molecular function | LIM domain binding |
| GO_0019904 | Molecular function | protein domain specific binding |
| GO_0008307 | Molecular function | structural constituent of muscle |
| GO_0031432 | Molecular function | titin binding |
| GO_0005546 | Molecular function | phosphatidylinositol-4,5-bisphosphate binding |
| GO_0051015 | Molecular function | actin filament binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0051373 | Molecular function | FATZ binding |
| GO_0005178 | Molecular function | integrin binding |
| GO_0070080 | Molecular function | titin Z domain binding |
| GO_0044325 | Molecular function | transmembrane transporter binding |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0008092 | Molecular function | cytoskeletal protein binding |
| GO_0030374 | Molecular function | nuclear receptor coactivator activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | ACTN2 |
| Protein name | Truncated actinin alpha 2 Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein) Actinin alpha 2 |
| Synonyms | |
| Description | FUNCTION: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
| Accessions | ENST00000651187.1 A0A7R6M8F2 ENST00000651275.1 A0A494C060 A0A494C166 A0A494C1A0 A0A7R6M6U5 A0A7R6M6R8 A0A804HI95 ENST00000651786.1 A0A804HKG0 A0A494C031 P35609 A0A7R6M8N3 A0A494C0Q3 ENST00000683111.1 ENST00000651781.1 ENST00000682015.1 ENST00000366578.6 [P35609-1] ENST00000652096.1 ENST00000651091.1 ENST00000542672.7 [P35609-2] A0A7R6M8N0 A0A494C033 |
