Interactors | Protein name | Directionality | Classification | |
|---|---|---|---|---|
| 1 | VCAM1-ITGA4+ITGB1 | VCAM1_HUMAN - | Ligand-Receptor | Adhesion by VCAM |
| 2 | VCAM1-ITGA9+ITGB1 | VCAM1_HUMAN - | Ligand-Receptor | Adhesion by VCAM |
| Name | filopodium |
| ID | GO_0030175 |
| collection_id | Cellular component |
| Alternative ID | GO:0030028 |
| Description | Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft. |
| Comment | A filopodium may be approximately 0.1 um wide, 5-10 um long, and up to 50 um long in axon growth cones; contain a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward. Note that filopodia on dendritic shafts are distinct from other types of filopodia (even those found in dendritic growth cones) and may react differently to stimuli, as shown in PMID:12904473. |
| External URL | |
| Genes | MYO6FSCN1SPEF1UBE2Q1MYO10SNAP25TIAM2ITGB1TWF2FGD4MYO3AB4GALT1VCAM1TUBB3IGF2BP1RAPH1LCP1ARL4CACP3LY6G6DEZRFAT1TWF1DAG1EPHA4TRPV4CD302DNALI1ACTG2INPPL1MSNFGF13ERMNACTA2ACTA1BAIAP2UTRNCXADRPDPNPODXLUNC5CCDC42DYNC2I2KITLGPPP1R9BRUFY3MYO1GGPM6ADYNC1H1SHTN1PPP1R9ARDXNF2TENM2DEF6SPATA13NOS1APSCIMPACTC1DMDWASH3PCDK5ITGA6FSCN3RAPGEF3NHERF1FARP1ADGRA2VIL1NGDNACTN2RIPOR2IQGAP2MTM1ENAHMYO1B |