ITGB1 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	52 studies	55% ± 22%	Explore
fibroblast	45 studies	56% ± 19%	Explore
pericyte	39 studies	67% ± 23%	Explore
macrophage	35 studies	37% ± 14%	Explore
natural killer cell	33 studies	37% ± 11%	Explore
smooth muscle cell	31 studies	67% ± 19%	Explore
T cell	29 studies	30% ± 11%	Explore
CD4-positive, alpha-beta T cell	26 studies	33% ± 16%	Explore
B cell	24 studies	24% ± 5%	Explore
endothelial cell of lymphatic vessel	23 studies	60% ± 20%	Explore
non-classical monocyte	23 studies	40% ± 16%	Explore
regulatory T cell	23 studies	38% ± 14%	Explore
classical monocyte	23 studies	32% ± 14%	Explore
conventional dendritic cell	22 studies	29% ± 11%	Explore
epithelial cell	21 studies	42% ± 19%	Explore
monocyte	20 studies	28% ± 10%	Explore
CD8-positive, alpha-beta T cell	20 studies	33% ± 12%	Explore
basal cell	20 studies	53% ± 20%	Explore
connective tissue cell	18 studies	61% ± 15%	Explore
capillary endothelial cell	17 studies	52% ± 20%	Explore
CD16-negative, CD56-bright natural killer cell, human	16 studies	38% ± 12%	Explore
mature NK T cell	16 studies	42% ± 12%	Explore
memory B cell	16 studies	28% ± 10%	Explore
endothelial cell of artery	16 studies	57% ± 23%	Explore
gamma-delta T cell	16 studies	31% ± 8%	Explore
myofibroblast cell	15 studies	66% ± 16%	Explore
dendritic cell	14 studies	33% ± 20%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	38% ± 7%	Explore
ciliated cell	14 studies	41% ± 18%	Explore
endothelial cell of vascular tree	14 studies	54% ± 18%	Explore
myeloid cell	14 studies	33% ± 15%	Explore
effector memory CD8-positive, alpha-beta T cell	13 studies	33% ± 14%	Explore
CD4-positive, alpha-beta memory T cell	13 studies	37% ± 14%	Explore
vein endothelial cell	13 studies	60% ± 17%	Explore
type I pneumocyte	11 studies	50% ± 14%	Explore
platelet	11 studies	45% ± 16%	Explore
club cell	11 studies	32% ± 17%	Explore
secretory cell	11 studies	43% ± 18%	Explore
type II pneumocyte	10 studies	30% ± 12%	Explore
plasma cell	10 studies	30% ± 10%	Explore
astrocyte	10 studies	28% ± 11%	Explore
adipocyte	10 studies	49% ± 19%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	30% ± 11%	Explore
innate lymphoid cell	9 studies	42% ± 16%	Explore
plasmablast	9 studies	46% ± 19%	Explore
leukocyte	9 studies	31% ± 9%	Explore
abnormal cell	9 studies	42% ± 21%	Explore
alveolar macrophage	8 studies	36% ± 11%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	8 studies	34% ± 11%	Explore
mesothelial cell	8 studies	43% ± 16%	Explore
microglial cell	8 studies	28% ± 6%	Explore
mucosal invariant T cell	8 studies	23% ± 7%	Explore
mast cell	7 studies	26% ± 9%	Explore
respiratory goblet cell	7 studies	32% ± 6%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	39% ± 14%	Explore
oligodendrocyte precursor cell	7 studies	28% ± 10%	Explore
neuron	7 studies	50% ± 13%	Explore
oligodendrocyte	7 studies	31% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	6 studies	34% ± 15%	Explore
plasmacytoid dendritic cell	6 studies	24% ± 5%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	44% ± 13%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	30% ± 11%	Explore
mononuclear phagocyte	6 studies	36% ± 13%	Explore
GABAergic neuron	6 studies	36% ± 15%	Explore
goblet cell	6 studies	41% ± 19%	Explore
glial cell	6 studies	35% ± 19%	Explore
lymphocyte	6 studies	42% ± 21%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	51% ± 12%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	32% ± 18%	Explore
enteroendocrine cell	5 studies	45% ± 20%	Explore
transit amplifying cell	5 studies	32% ± 24%	Explore
brush cell	5 studies	44% ± 23%	Explore
adventitial cell	5 studies	49% ± 15%	Explore
cardiac muscle cell	5 studies	35% ± 2%	Explore
T follicular helper cell	5 studies	26% ± 10%	Explore
myoepithelial cell	5 studies	57% ± 19%	Explore
hepatocyte	5 studies	50% ± 31%	Explore
erythrocyte	5 studies	31% ± 13%	Explore
interneuron	5 studies	36% ± 23%	Explore
CD4-positive helper T cell	4 studies	33% ± 11%	Explore
deuterosomal cell	4 studies	27% ± 10%	Explore
duct epithelial cell	4 studies	25% ± 7%	Explore
squamous epithelial cell	4 studies	45% ± 21%	Explore
pancreatic A cell	4 studies	78% ± 12%	Explore
type B pancreatic cell	4 studies	41% ± 20%	Explore
cholangiocyte	4 studies	44% ± 23%	Explore
glomerular endothelial cell	4 studies	75% ± 4%	Explore
progenitor cell	4 studies	44% ± 21%	Explore
megakaryocyte	4 studies	56% ± 13%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	41% ± 10%	Explore
glutamatergic neuron	4 studies	44% ± 9%	Explore
group 3 innate lymphoid cell	4 studies	50% ± 10%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	50% ± 8%	Explore
hillock cell	3 studies	25% ± 6%	Explore
ionocyte	3 studies	42% ± 18%	Explore
pancreatic D cell	3 studies	64% ± 22%	Explore
naive B cell	3 studies	21% ± 3%	Explore
hepatic stellate cell	3 studies	42% ± 18%	Explore
exhausted T cell	3 studies	36% ± 6%	Explore
hematopoietic precursor cell	3 studies	32% ± 9%	Explore
podocyte	3 studies	79% ± 3%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	41% ± 3%	Explore
epithelial cell of proximal tubule	3 studies	25% ± 9%	Explore
neural crest cell	3 studies	41% ± 5%	Explore
kidney loop of Henle epithelial cell	3 studies	35% ± 7%	Explore
extravillous trophoblast	3 studies	87% ± 4%	Explore
placental villous trophoblast	3 studies	71% ± 20%	Explore
Schwann cell	3 studies	56% ± 14%	Explore
pro-B cell	3 studies	20% ± 6%	Explore
tissue-resident macrophage	3 studies	29% ± 3%	Explore
Mueller cell	3 studies	22% ± 2%	Explore
IgG plasma cell	3 studies	22% ± 5%	Explore
endothelial cell of sinusoid	3 studies	52% ± 25%	Explore
luminal cell of prostate epithelium	3 studies	28% ± 5%	Explore
muscle cell	3 studies	70% ± 10%	Explore
pancreatic ductal cell	3 studies	87% ± 5%	Explore
granulocyte	3 studies	24% ± 7%	Explore
hematopoietic stem cell	3 studies	44% ± 14%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	54% ± 6%	Explore
melanocyte	3 studies	37% ± 12%	Explore
keratinocyte	3 studies	27% ± 7%	Explore
erythroblast	3 studies	55% ± 23%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	51% ± 14%	Explore
double negative thymocyte	3 studies	37% ± 7%	Explore
IgA plasma cell	3 studies	19% ± 3%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	18 studies	45% ± 15%	Explore
peripheral blood	17 studies	33% ± 10%	Explore
brain	11 studies	29% ± 12%	Explore
intestine	8 studies	39% ± 19%	Explore
kidney	8 studies	37% ± 11%	Explore
liver	7 studies	36% ± 14%	Explore
heart	5 studies	33% ± 9%	Explore
pancreas	4 studies	61% ± 17%	Explore
bone marrow	4 studies	36% ± 14%	Explore
eye	4 studies	28% ± 12%	Explore
uterus	4 studies	67% ± 10%	Explore
breast	4 studies	46% ± 13%	Explore
prostate	4 studies	44% ± 15%	Explore
adipose	4 studies	40% ± 15%	Explore
placenta	3 studies	72% ± 14%	Explore
lymph node	3 studies	28% ± 8%	Explore
skin	3 studies	31% ± 13%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	21877.20	576 / 578	100%	87.64	1150 / 1155
intestine	99%	20056.96	957 / 966	98%	70.54	519 / 527
breast	100%	22668.33	459 / 459	97%	100.25	1089 / 1118
bladder	100%	19442.00	21 / 21	94%	64.63	474 / 504
uterus	100%	23726.57	170 / 170	90%	63.70	415 / 459
esophagus	90%	25037.78	1297 / 1445	100%	92.34	183 / 183
thymus	98%	11544.09	643 / 653	89%	48.47	538 / 605
ovary	93%	12125.06	168 / 180	91%	44.78	393 / 430
adrenal gland	90%	10201.23	232 / 258	89%	56.99	204 / 230
stomach	80%	13131.96	288 / 359	98%	77.56	280 / 286
skin	87%	32231.24	1565 / 1809	91%	71.99	431 / 472
prostate	83%	11825.86	204 / 245	92%	51.68	460 / 502
kidney	75%	7551.28	67 / 89	91%	84.34	824 / 901
pancreas	60%	4565.74	196 / 328	97%	118.97	173 / 178
liver	53%	5016.01	120 / 226	83%	54.92	337 / 406
adipose	100%	27891.72	1204 / 1204	0%	0	0 / 0
blood vessel	100%	55768.37	1335 / 1335	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	16.56	1 / 1
muscle	95%	9893.82	760 / 803	0%	0	0 / 0
brain	20%	1479.93	531 / 2642	72%	24.00	505 / 705
heart	91%	17262.21	785 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	91%	56.92	41 / 45
spleen	90%	8879.57	216 / 241	0%	0	0 / 0
eye	0%	0	0 / 0	74%	24.61	59 / 80
lymph node	0%	0	0 / 0	45%	15.65	13 / 29
peripheral blood	21%	1507.68	199 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0002052	Biological process	positive regulation of neuroblast proliferation
GO_0031623	Biological process	receptor internalization
GO_0033627	Biological process	cell adhesion mediated by integrin
GO_0006909	Biological process	phagocytosis
GO_0051897	Biological process	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
GO_0030183	Biological process	B cell differentiation
GO_0051726	Biological process	regulation of cell cycle
GO_0035024	Biological process	negative regulation of Rho protein signal transduction
GO_0023035	Biological process	CD40 signaling pathway
GO_0001701	Biological process	in utero embryonic development
GO_0043547	Biological process	positive regulation of GTPase activity
GO_0045766	Biological process	positive regulation of angiogenesis
GO_0150103	Biological process	reactive gliosis
GO_0060912	Biological process	cardiac cell fate specification
GO_0010763	Biological process	positive regulation of fibroblast migration
GO_0000132	Biological process	establishment of mitotic spindle orientation
GO_2000811	Biological process	negative regulation of anoikis
GO_0007155	Biological process	cell adhesion
GO_0034113	Biological process	heterotypic cell-cell adhesion
GO_1901979	Biological process	regulation of inward rectifier potassium channel activity
GO_0030030	Biological process	cell projection organization
GO_1900748	Biological process	positive regulation of vascular endothelial growth factor signaling pathway
GO_0008542	Biological process	visual learning
GO_0071711	Biological process	basement membrane organization
GO_0007229	Biological process	integrin-mediated signaling pathway
GO_0007156	Biological process	homophilic cell adhesion via plasma membrane adhesion molecules
GO_0048626	Biological process	myoblast fate specification
GO_0050901	Biological process	leukocyte tethering or rolling
GO_0045214	Biological process	sarcomere organization
GO_0045906	Biological process	negative regulation of vasoconstriction
GO_0035313	Biological process	wound healing, spreading of epidermal cells
GO_0007405	Biological process	neuroblast proliferation
GO_1905806	Biological process	regulation of synapse pruning
GO_0033631	Biological process	cell-cell adhesion mediated by integrin
GO_0048813	Biological process	dendrite morphogenesis
GO_0048333	Biological process	mesodermal cell differentiation
GO_0046718	Biological process	symbiont entry into host cell
GO_0060379	Biological process	cardiac muscle cell myoblast differentiation
GO_0045445	Biological process	myoblast differentiation
GO_0007517	Biological process	muscle organ development
GO_0021943	Biological process	formation of radial glial scaffolds
GO_0048675	Biological process	axon extension
GO_0010710	Biological process	regulation of collagen catabolic process
GO_0007520	Biological process	myoblast fusion
GO_0043065	Biological process	positive regulation of apoptotic process
GO_0016477	Biological process	cell migration
GO_0000082	Biological process	G1/S transition of mitotic cell cycle
GO_0051951	Biological process	positive regulation of glutamate uptake involved in transmission of nerve impulse
GO_0031589	Biological process	cell-substrate adhesion
GO_0055007	Biological process	cardiac muscle cell differentiation
GO_0007160	Biological process	cell-matrix adhesion
GO_0030032	Biological process	lamellipodium assembly
GO_0002042	Biological process	cell migration involved in sprouting angiogenesis
GO_0030198	Biological process	extracellular matrix organization
GO_0006968	Biological process	cellular defense response
GO_1903078	Biological process	positive regulation of protein localization to plasma membrane
GO_0071404	Biological process	cellular response to low-density lipoprotein particle stimulus
GO_0045665	Biological process	negative regulation of neuron differentiation
GO_0045743	Biological process	positive regulation of fibroblast growth factor receptor signaling pathway
GO_0030335	Biological process	positive regulation of cell migration
GO_0035633	Biological process	maintenance of blood-brain barrier
GO_0150003	Biological process	regulation of spontaneous synaptic transmission
GO_0043149	Biological process	stress fiber assembly
GO_0008354	Biological process	germ cell migration
GO_0098609	Biological process	cell-cell adhesion
GO_0007161	Biological process	calcium-independent cell-matrix adhesion
GO_0007179	Biological process	transforming growth factor beta receptor signaling pathway
GO_0007159	Biological process	leukocyte cell-cell adhesion
GO_0090303	Biological process	positive regulation of wound healing
GO_0034674	Cellular component	integrin alpha5-beta1 complex
GO_0098685	Cellular component	Schaffer collateral - CA1 synapse
GO_0045121	Cellular component	membrane raft
GO_0034666	Cellular component	integrin alpha2-beta1 complex
GO_0034679	Cellular component	integrin alpha9-beta1 complex
GO_0008305	Cellular component	integrin complex
GO_0034665	Cellular component	integrin alpha1-beta1 complex
GO_0009986	Cellular component	cell surface
GO_0035748	Cellular component	myelin sheath abaxonal region
GO_0010008	Cellular component	endosome membrane
GO_0034677	Cellular component	integrin alpha7-beta1 complex
GO_0034667	Cellular component	integrin alpha3-beta1 complex
GO_0150053	Cellular component	cerebellar climbing fiber to Purkinje cell synapse
GO_0034668	Cellular component	integrin alpha4-beta1 complex
GO_0001726	Cellular component	ruffle
GO_0097060	Cellular component	synaptic membrane
GO_0070062	Cellular component	extracellular exosome
GO_0030175	Cellular component	filopodium
GO_0030027	Cellular component	lamellipodium
GO_0034682	Cellular component	integrin alphav-beta1 complex
GO_0014704	Cellular component	intercalated disc
GO_0009897	Cellular component	external side of plasma membrane
GO_0043235	Cellular component	receptor complex
GO_0005886	Cellular component	plasma membrane
GO_0034681	Cellular component	integrin alpha11-beta1 complex
GO_0016020	Cellular component	membrane
GO_0055037	Cellular component	recycling endosome
GO_0034675	Cellular component	integrin alpha6-beta1 complex
GO_0034678	Cellular component	integrin alpha8-beta1 complex
GO_0005737	Cellular component	cytoplasm
GO_0097386	Cellular component	glial cell projection
GO_0032587	Cellular component	ruffle membrane
GO_0034680	Cellular component	integrin alpha10-beta1 complex
GO_0031594	Cellular component	neuromuscular junction
GO_0043197	Cellular component	dendritic spine
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0042383	Cellular component	sarcolemma
GO_0005925	Cellular component	focal adhesion
GO_0045202	Cellular component	synapse
GO_0032154	Cellular component	cleavage furrow
GO_0042470	Cellular component	melanosome
GO_0001618	Molecular function	virus receptor activity
GO_0046982	Molecular function	protein heterodimerization activity
GO_0005509	Molecular function	calcium ion binding
GO_0015026	Molecular function	coreceptor activity
GO_0098639	Molecular function	collagen binding involved in cell-matrix adhesion
GO_0050839	Molecular function	cell adhesion molecule binding
GO_0043236	Molecular function	laminin binding
GO_0003779	Molecular function	actin binding
GO_0019960	Molecular function	C-X3-C chemokine binding
GO_0001968	Molecular function	fibronectin binding
GO_1990782	Molecular function	protein tyrosine kinase binding
GO_0000287	Molecular function	magnesium ion binding
GO_0002020	Molecular function	protease binding
GO_0005515	Molecular function	protein binding
GO_0044877	Molecular function	protein-containing complex binding
GO_0045296	Molecular function	cadherin binding
GO_0019901	Molecular function	protein kinase binding
GO_0005178	Molecular function	integrin binding
GO_0098640	Molecular function	integrin binding involved in cell-matrix adhesion

IV. Literature review

[source]

Gene name	ITGB1
Protein name	Integrin beta-1 Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) (GPIIA) (VLA-4 subunit beta) (CD antigen CD29) Integrin beta Integrin subunit beta 1
Synonyms	MDF2 FNRB MSK12
Description	FUNCTION: Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion (By similarity). Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. When associated with alpha-7 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nodules. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and RACK1, serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successful completion of cytokinesis. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. ITGA4:ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling . ITGA4:ITGB1 and ITGA5:ITGB1 bind to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 . ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 . ITGA5:ITGB1 acts as a receptor for fibronectin FN1 and mediates R-G-D-dependent cell adhesion to FN1 . ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling . ITGA5:ITGB3 is a receptor for soluble CD40LG and is required for CD40/CD40LG signaling . Plays an important role in myoblast differentiation and fusion during skeletal myogenesis (By similarity). ITGA9:ITGB1 may play a crucial role in SVEP1/polydom-mediated myoblast cell adhesion (By similarity). Integrins ITGA9:ITGB1 and ITGA4:ITGB1 repress PRKCA-mediated L-type voltage-gated channel Ca(2+) influx and ROCK-mediated calcium sensitivity in vascular smooth muscle cells via their interaction with SVEP1, thereby inhibit vasocontraction . .; FUNCTION: [Isoform 2]: Interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). .; FUNCTION: [Isoform 5]: Isoform 5 displaces isoform 1 in striated muscles. .; FUNCTION: (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8. .; FUNCTION: (Microbial infection) Acts as a receptor for Cytomegalovirus/HHV-5. .; FUNCTION: (Microbial infection) Acts as a receptor for Epstein-Barr virus/HHV-4. .; FUNCTION: (Microbial infection) Integrin ITGA5:ITGB1 acts as a receptor for Human parvovirus B19. .; FUNCTION: (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus. .; FUNCTION: (Microbial infection) Acts as a receptor for Mammalian reovirus. .; FUNCTION: (Microbial infection) In case of HIV-1 infection, integrin ITGA5:ITGB1 binding to extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. .; FUNCTION: (Microbial infection) Interacts with CotH proteins expressed by fungi of the order mucorales, the causative agent of mucormycosis, which plays an important role in epithelial cell invasion by the fungi . Integrin ITGA3:ITGB1 may act as a receptor for R.delemar CotH7 in alveolar epithelial cells, which may be an early step in pulmonary mucormycosis disease progression . .; FUNCTION: (Microbial infection) May serve as a receptor for adhesin A (nadA) of N.meningitidis. .
Accessions	ENST00000437302.6 [P05556-1] Q5T3E4 ENST00000534049.5 ENST00000474568.6 ENST00000423113.6 [P05556-5] ENST00000488494.6 ENST00000677999.1 [P05556-1] A0A7I2V2T4 ENST00000480226.5 ENST00000678766.1 [P05556-3] ENST00000396033.6 [P05556-1] A0A7I2V348 C9JNE0 ENST00000472147.1 ENST00000488427.2 ENST00000678591.1 ENST00000417122.7 [P05556-1] ENST00000679187.1 ENST00000437302 ENST00000677363.1 ENST00000528877.5 ENST00000676895.1 A0A7I2V2F9 ENST00000676964.1 ENST00000302278.8 [P05556-1] ENST00000414670.2 E9PLR6 Q5T3E5 ENST00000676460.1 [P05556-2] ENST00000678120.1 Q5T3E6 E7EUI6 ENST00000609742.3 ENST00000678989.1 [P05556-1] E7EQW5 H7C4K3 ENST00000678952.1 [P05556-1] ENST00000678701.1 [P05556-1] ENST00000677310.1 [P05556-3] ENST00000494395.1 A0A7I2V5T3 ENST00000417122 C9JPK5 P05556 ENST00000676659.1 [P05556-4] E9PQJ2 H7C4N8 ENST00000678479.1 ENST00000678943.1 [P05556-1] A0A7I2V5Z8

ITGB1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review