Interactors | Protein name | Directionality | Classification | |
---|---|---|---|---|
1 | DSC2-DSG2 | DSC2_HUMAN - DSG2_HUMAN | Adhesion-Adhesion | Adhesion by Desmosome |
2 | GJA1-GJA5 | CXA1_HUMAN - CXA5_HUMAN | Gap-Gap | Adhesion by GAP junction |
3 | GJC1-GJA1 | CXG1_HUMAN - CXA1_HUMAN | Gap-Gap | Adhesion by GAP junction |
4 | GJC1-GJA5 | CXG1_HUMAN - CXA5_HUMAN | Gap-Gap | Adhesion by GAP junction |
Name | intercalated disc |
ID | GO_0014704 |
collection_id | Cellular component |
Exact synonym | intercalated disk |
Description | A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells. |
External URL | |
Genes |