Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 10 studies | 34% ± 16% | |
| macrophage | 5 studies | 20% ± 4% | |
| basal cell | 5 studies | 31% ± 13% | |
| enterocyte | 4 studies | 23% ± 6% | |
| extravillous trophoblast | 3 studies | 44% ± 10% | |
| placental villous trophoblast | 3 studies | 27% ± 7% | |
| myeloid cell | 3 studies | 17% ± 2% | |
| luminal cell of prostate epithelium | 3 studies | 35% ± 8% | |
| goblet cell | 3 studies | 29% ± 7% | |
| transit amplifying cell | 3 studies | 32% ± 16% | |
| keratinocyte | 3 studies | 22% ± 5% |
Insufficient scRNA-seq data for expression of DSC2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| pancreas | 97% | 1105.66 | 319 / 328 | 89% | 16.79 | 159 / 178 |
| prostate | 85% | 1093.72 | 208 / 245 | 97% | 29.52 | 485 / 502 |
| breast | 99% | 1686.94 | 456 / 459 | 81% | 27.42 | 905 / 1118 |
| lung | 87% | 742.36 | 504 / 578 | 87% | 31.08 | 1005 / 1155 |
| kidney | 97% | 787.57 | 86 / 89 | 61% | 7.86 | 554 / 901 |
| intestine | 60% | 3013.36 | 584 / 966 | 94% | 28.38 | 493 / 527 |
| stomach | 66% | 960.00 | 236 / 359 | 81% | 20.29 | 233 / 286 |
| esophagus | 45% | 14518.16 | 644 / 1445 | 96% | 103.51 | 175 / 183 |
| thymus | 75% | 382.33 | 493 / 653 | 58% | 8.68 | 353 / 605 |
| liver | 88% | 500.65 | 198 / 226 | 19% | 2.42 | 77 / 406 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 103.69 | 44 / 45 |
| adipose | 98% | 956.42 | 1174 / 1204 | 0% | 0 | 0 / 0 |
| ovary | 7% | 32.31 | 13 / 180 | 86% | 22.15 | 371 / 430 |
| bladder | 24% | 86.19 | 5 / 21 | 67% | 23.56 | 340 / 504 |
| heart | 90% | 1166.71 | 776 / 861 | 0% | 0 | 0 / 0 |
| uterus | 6% | 599.46 | 11 / 170 | 79% | 54.67 | 364 / 459 |
| spleen | 83% | 671.78 | 201 / 241 | 0% | 0 | 0 / 0 |
| skin | 72% | 1565.60 | 1308 / 1809 | 10% | 3.23 | 47 / 472 |
| peripheral blood | 65% | 1622.70 | 605 / 929 | 0% | 0 | 0 / 0 |
| adrenal gland | 50% | 248.96 | 129 / 258 | 0% | 0.05 | 1 / 230 |
| blood vessel | 21% | 109.82 | 286 / 1335 | 0% | 0 | 0 / 0 |
| brain | 20% | 90.01 | 519 / 2642 | 1% | 0.13 | 10 / 705 |
| lymph node | 0% | 0 | 0 / 0 | 3% | 0.29 | 1 / 29 |
| muscle | 0% | 4.89 | 4 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0086042 | Biological process | cardiac muscle cell-cardiac muscle cell adhesion |
| GO_0007155 | Biological process | cell adhesion |
| GO_0009267 | Biological process | cellular response to starvation |
| GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO_0086091 | Biological process | regulation of heart rate by cardiac conduction |
| GO_0098911 | Biological process | regulation of ventricular cardiac muscle cell action potential |
| GO_0098609 | Biological process | cell-cell adhesion |
| GO_0086073 | Biological process | bundle of His cell-Purkinje myocyte adhesion involved in cell communication |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0031410 | Cellular component | cytoplasmic vesicle |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0001533 | Cellular component | cornified envelope |
| GO_0005783 | Cellular component | endoplasmic reticulum |
| GO_0005912 | Cellular component | adherens junction |
| GO_0030057 | Cellular component | desmosome |
| GO_0014704 | Cellular component | intercalated disc |
| GO_0086083 | Molecular function | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication |
| GO_0005509 | Molecular function | calcium ion binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | DSC2 |
| Protein name | Desmocollin 2 Desmocollin-2 (Cadherin family member 2) (Desmocollin-3) (Desmosomal glycoprotein II) (Desmosomal glycoprotein III) |
| Synonyms | DSC3 CDHF2 |
| Description | FUNCTION: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms. FUNCTION: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. . FUNCTION: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. . FUNCTION: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. . |
| Accessions | A9X9L1 A0A3B3ISU0 ENST00000251081.8 [Q02487-2] ENST00000648081.1 ENST00000682357.1 A9X9K9 ENST00000280904.11 [Q02487-1] Q02487 A9X9L0 |
