GO_0005912 | OmnibusX

adherens junction

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	DLL1-NOTCH1	DLL1_HUMAN - NOTC1_HUMAN	Ligand-Receptor	Signaling by Notch
2	EFNA5-EPHA4	EFNA5_HUMAN - EPHA4_HUMAN	Ligand-Receptor	Signaling by Ephrin
3	EFNB2-EPHA4	EFNB2_HUMAN - EPHA4_HUMAN	Ligand-Receptor	Signaling by Ephrin
4	JAG1-NOTCH1	JAG1_HUMAN - NOTC1_HUMAN	Ligand-Receptor	Signaling by Notch
5	NECTIN1-NECTIN3	PVRL1_HUMAN - PVRL3_HUMAN	Adhesion-Adhesion	Adhesion by Nectin
6	NECTIN1-NECTIN4	PVRL1_HUMAN - PVRL4_HUMAN	Adhesion-Adhesion	Adhesion by Nectin
7	NECTIN3-PVR	PVRL3_HUMAN - PVR_HUMAN	Ligand-Receptor	Signaling by Nectin

II. Literature review

Name	adherens junction
ID	GO_0005912
collection_id	Cellular component
Alternative ID	GO:0005913
Exact synonym	cell-cell adherens junction
Description	A cell-cell junction composed of the epithelial cadherin-catenin complex. The epithelial cadherins, or E-cadherins, of each interacting cell extend through the plasma membrane into the extracellular space and bind to each other. The E-cadherins bind to catenins on the cytoplasmic side of the membrane, where the E-cadherin-catenin complex binds to cytoskeletal components and regulatory and signaling molecules.
External URL
Genes	EIF4G2 NPHP1 CTNND2 AJM1 AHI1 PDLIM4 TNKS1BP1 CDH11 OXTR XIRP1 ESAM CCDC85B PKP2 PARD3B MYO1E TJP1 NIBAN2 WNK3 DAG1 EPHA4 TMEM47 PTPRM JAG1 MSN NECTIN1 BMPR2 PARK7 DLL1 AJUBA SNAP23 FRS2 TJP2 CDH24 CDH15 PPP1R9B FERMT2 JUP PKP3 CDH26 RDX POF1B CRB1 MPP4 FRMD4B ABI2 ADAM15 IGSF21 ITGA6 ANXA2 DSP SORBS1 scribble_human PPP1CA MPP7 FLOT2 CDH5 SH3BP1 LAMA3 PIP5K1C ALOX15B CCDC85A NECTIN3 DLG4 LIMD1 scribble_human-3 LRRC7 CTNND1 CDH18 CDH8 PDLIM2 FRMD5 PKP1 DLG1 scribble_human-4 PDZD11 TRIM29 scribble_human-9 CXADR ADAM10 CDH19 EPB41L5 CTNNA1 BAIAP2L1 CDH20 LDB3 CDCA3 KRT18 CDH3 TMOD3 TNK2 LLGL1 MAGI1 CDHR3 SCRIB HMCN1 S100A11 CDH6 SHROOM1 DSC2 APC ACTB SYNM PDLIM7 CCDC85C SSX2IP TLN1 PKP4 EZR CDC42EP4 scribble_human-2 ANXA1 PARD3 DLG3 CDH10 FRMD4A BAIAP2 CYTH1 NOTCH1 LLGL2 LYN CTNNA2 TSPAN33 AJAP1 KLHL24 CDH4 CDH2 VEGFA CDH13 PTPRK MPP3 AFDN TMEM204 SMAD7 scribble_human-6 SHROOM3 PLPP3 CYTH3 SDCBP EFNA5 scribble_human-5 CEACAM1 PDLIM1 PDLIM3 SPTBN4 CD99L2 WTIP FLOT1 ARHGAP24 scribble_human-7 PALS1 NECTIN4 STXBP6 NEXN RND1 ADD1 DLG2 TBCD SHROOM4 scribble_human-8 FAT2 CDH7 TRPV4 CDH17 ARVCF CYTH2 PAK4 CNN3 CTNNA3 CTNNB1 CDH1 PDLIM5 CDH12 NF2 ZYX PVR VCL FMN1 DLG5 RAB10 VEZT MYH9 scribble_human-1 FER PGM5 JCAD CDH22 SHROOM2 CDC42EP1 CDH9 EFNB2 PRICKLE4 NDRG1