Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 42 studies | 51% ± 22% | |
pericyte | 26 studies | 36% ± 20% | |
smooth muscle cell | 15 studies | 31% ± 13% | |
capillary endothelial cell | 15 studies | 60% ± 19% | |
endothelial cell of artery | 14 studies | 55% ± 22% | |
vein endothelial cell | 13 studies | 49% ± 20% | |
endothelial cell of vascular tree | 13 studies | 50% ± 18% | |
platelet | 9 studies | 40% ± 12% | |
megakaryocyte | 5 studies | 66% ± 17% | |
glomerular endothelial cell | 4 studies | 59% ± 6% | |
type II pneumocyte | 3 studies | 30% ± 13% |
Insufficient scRNA-seq data for expression of ESAM at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 12729.92 | 653 / 653 | 97% | 150.00 | 586 / 605 |
breast | 100% | 8963.67 | 459 / 459 | 95% | 37.27 | 1067 / 1118 |
lung | 100% | 13125.51 | 578 / 578 | 93% | 38.61 | 1073 / 1155 |
kidney | 100% | 4280.94 | 89 / 89 | 92% | 109.16 | 832 / 901 |
bladder | 95% | 3518.76 | 20 / 21 | 86% | 27.09 | 434 / 504 |
esophagus | 92% | 2795.52 | 1333 / 1445 | 87% | 26.72 | 159 / 183 |
stomach | 90% | 1956.49 | 322 / 359 | 89% | 31.89 | 255 / 286 |
adrenal gland | 80% | 1627.14 | 207 / 258 | 93% | 50.95 | 215 / 230 |
prostate | 91% | 2495.81 | 222 / 245 | 80% | 18.89 | 400 / 502 |
uterus | 100% | 4977.78 | 170 / 170 | 69% | 17.84 | 316 / 459 |
intestine | 80% | 2120.98 | 775 / 966 | 87% | 25.60 | 461 / 527 |
brain | 62% | 1249.51 | 1629 / 2642 | 100% | 48.72 | 704 / 705 |
ovary | 53% | 1403.41 | 95 / 180 | 75% | 15.42 | 322 / 430 |
skin | 53% | 1241.52 | 951 / 1809 | 67% | 16.30 | 315 / 472 |
pancreas | 19% | 302.56 | 62 / 328 | 98% | 45.28 | 175 / 178 |
adipose | 100% | 10495.61 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 9414.72 | 1335 / 1335 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 44.63 | 1 / 1 |
liver | 16% | 256.99 | 36 / 226 | 84% | 22.58 | 341 / 406 |
heart | 99% | 4273.67 | 854 / 861 | 0% | 0 | 0 / 0 |
spleen | 94% | 2125.41 | 227 / 241 | 0% | 0 | 0 / 0 |
muscle | 81% | 1623.44 | 652 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 73% | 15.26 | 33 / 45 |
lymph node | 0% | 0 | 0 / 0 | 59% | 9.76 | 17 / 29 |
peripheral blood | 21% | 562.18 | 191 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 19% | 2.82 | 15 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0008104 | Biological process | protein localization |
GO_0007156 | Biological process | homophilic cell adhesion via plasma membrane adhesion molecules |
GO_0030833 | Biological process | regulation of actin filament polymerization |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0070830 | Biological process | bicellular tight junction assembly |
GO_0032956 | Biological process | regulation of actin cytoskeleton organization |
GO_0035633 | Biological process | maintenance of blood-brain barrier |
GO_0005911 | Cellular component | cell-cell junction |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005912 | Cellular component | adherens junction |
GO_0005886 | Cellular component | plasma membrane |
GO_0005923 | Cellular component | bicellular tight junction |
GO_0098632 | Molecular function | cell-cell adhesion mediator activity |
GO_0005515 | Molecular function | protein binding |
Gene name | ESAM |
Protein name | Endothelial cell-selective adhesion molecule Endothelial cell adhesion molecule |
Synonyms | UNQ220/PRO246 |
Description | FUNCTION: Can mediate aggregation most likely through a homophilic molecular interaction. . |
Accessions | C9JIE7 F8WDW9 Q96AP7 ENST00000417453.5 ENST00000278927.10 [Q96AP7-1] ENST00000444566.5 [Q96AP7-2] ENST00000435477.1 |