CDH13 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	19 studies	37% ± 16%	Explore
oligodendrocyte precursor cell	15 studies	57% ± 19%	Explore
glutamatergic neuron	12 studies	45% ± 17%	Explore
smooth muscle cell	11 studies	28% ± 7%	Explore
fibroblast	11 studies	25% ± 7%	Explore
GABAergic neuron	10 studies	52% ± 21%	Explore
oligodendrocyte	9 studies	34% ± 21%	Explore
endothelial cell of lymphatic vessel	8 studies	33% ± 8%	Explore
pericyte	7 studies	30% ± 11%	Explore
neuron	6 studies	27% ± 9%	Explore
interneuron	6 studies	48% ± 21%	Explore
capillary endothelial cell	6 studies	30% ± 5%	Explore
cardiac muscle cell	6 studies	73% ± 15%	Explore
endothelial cell of vascular tree	5 studies	30% ± 11%	Explore
astrocyte	4 studies	36% ± 31%	Explore
endothelial cell of artery	4 studies	26% ± 2%	Explore
glomerular endothelial cell	3 studies	28% ± 1%	Explore
GABAergic interneuron	3 studies	49% ± 12%	Explore
microglial cell	3 studies	44% ± 28%	Explore
basal cell	3 studies	46% ± 26%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
brain	15 studies	36% ± 18%	Explore
heart	6 studies	34% ± 12%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
breast	89%	2200.97	409 / 459	83%	2.89	926 / 1118
lung	97%	3515.81	559 / 578	67%	3.33	779 / 1155
skin	100%	5254.54	1802 / 1809	52%	2.94	244 / 472
uterus	98%	6971.80	166 / 170	51%	3.22	233 / 459
esophagus	40%	526.39	583 / 1445	96%	9.11	176 / 183
brain	43%	1401.82	1145 / 2642	86%	6.59	606 / 705
intestine	43%	643.08	418 / 966	81%	2.56	426 / 527
bladder	57%	805.81	12 / 21	55%	2.24	277 / 504
stomach	15%	194.96	54 / 359	87%	3.03	249 / 286
blood vessel	100%	18963.92	1335 / 1335	0%	0	0 / 0
heart	96%	5343.83	825 / 861	0%	0	0 / 0
adipose	95%	2782.46	1142 / 1204	0%	0	0 / 0
muscle	95%	2802.72	761 / 803	0%	0	0 / 0
thymus	17%	235.45	112 / 653	77%	3.21	466 / 605
prostate	39%	574.16	96 / 245	50%	1.05	249 / 502
kidney	21%	343.49	19 / 89	67%	10.03	602 / 901
tonsil	0%	0	0 / 0	67%	3.37	30 / 45
adrenal gland	2%	18.66	5 / 258	63%	3.43	145 / 230
pancreas	0%	0	0 / 328	52%	1.27	93 / 178
ovary	18%	385.39	32 / 180	31%	0.95	135 / 430
liver	0%	0	0 / 226	39%	0.83	160 / 406
lymph node	0%	0	0 / 0	21%	0.38	6 / 29
eye	0%	0	0 / 0	6%	0.09	5 / 80
spleen	3%	31.97	8 / 241	0%	0	0 / 0
peripheral blood	0%	2.16	2 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

III. Associated gene sets

GO_0007043	Biological process	cell-cell junction assembly
GO_0008285	Biological process	negative regulation of cell population proliferation
GO_0034332	Biological process	adherens junction organization
GO_0050850	Biological process	positive regulation of calcium-mediated signaling
GO_0030032	Biological process	lamellipodium assembly
GO_0048661	Biological process	positive regulation of smooth muscle cell proliferation
GO_0001954	Biological process	positive regulation of cell-matrix adhesion
GO_0007275	Biological process	multicellular organism development
GO_0007162	Biological process	negative regulation of cell adhesion
GO_0055096	Biological process	low-density lipoprotein particle mediated signaling
GO_0044331	Biological process	cell-cell adhesion mediated by cadherin
GO_0042058	Biological process	regulation of epidermal growth factor receptor signaling pathway
GO_0002040	Biological process	sprouting angiogenesis
GO_0001938	Biological process	positive regulation of endothelial cell proliferation
GO_0030335	Biological process	positive regulation of cell migration
GO_0007156	Biological process	homophilic cell adhesion via plasma membrane adhesion molecules
GO_0043542	Biological process	endothelial cell migration
GO_0051668	Biological process	localization within membrane
GO_0016601	Biological process	Rac protein signal transduction
GO_0016339	Biological process	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO_0030100	Biological process	regulation of endocytosis
GO_0043616	Biological process	keratinocyte proliferation
GO_0007266	Biological process	Rho protein signal transduction
GO_0000902	Biological process	cell morphogenesis
GO_0050927	Biological process	positive regulation of positive chemotaxis
GO_0016477	Biological process	cell migration
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0005615	Cellular component	extracellular space
GO_0009897	Cellular component	external side of plasma membrane
GO_0005576	Cellular component	extracellular region
GO_0005886	Cellular component	plasma membrane
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0070062	Cellular component	extracellular exosome
GO_0062023	Cellular component	collagen-containing extracellular matrix
GO_0043005	Cellular component	neuron projection
GO_0016342	Cellular component	catenin complex
GO_0005925	Cellular component	focal adhesion
GO_0098982	Cellular component	GABA-ergic synapse
GO_0005912	Cellular component	adherens junction
GO_0005737	Cellular component	cytoplasm
GO_0005901	Cellular component	caveola
GO_0045296	Molecular function	cadherin binding
GO_0071813	Molecular function	lipoprotein particle binding
GO_0042802	Molecular function	identical protein binding
GO_0008013	Molecular function	beta-catenin binding
GO_0030169	Molecular function	low-density lipoprotein particle binding
GO_0055100	Molecular function	adiponectin binding
GO_0005509	Molecular function	calcium ion binding
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	CDH13
Protein name	Cadherin-13 (Heart cadherin) (H-cadherin) (P105) (Truncated cadherin) (T-cad) (T-cadherin) Cadherin 13
Synonyms	CDHH
Description	FUNCTION: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth. .
Accessions	ENST00000431540.7 [P55290-2] H3BTF2 ENST00000569144.5 P55290 H3BV21 ENST00000567109.6 [P55290-1] ENST00000428848.7 [P55290-5] F5H7W7 ENST00000539548.6 H3BRL7 ENST00000565636.5 [P55290-3] H3BQH4 ENST00000268613.14 [P55290-4] ENST00000568770.5 ENST00000562601.5 ENST00000567445.1

CDH13 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review