sprouting angiogenesis

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1ANGPT1-TEKANGP1_HUMAN - TIE2_HUMANLigand-ReceptorSignaling by Angiopoietin
2PGF-NRP1PLGF_HUMAN - NRP1_HUMANLigand-ReceptorSignaling by Placenta growth factor
3VEGFA-NRP1VEGFA_HUMAN - NRP1_HUMANLigand-ReceptorSignaling by Vascular endothelial growth factor
4VEGFB-NRP1VEGFB_HUMAN - NRP1_HUMANLigand-ReceptorSignaling by Vascular endothelial growth factor
5VEGFC-FLT4VEGFC_HUMAN - VGFR3_HUMANLigand-ReceptorSignaling by Vascular endothelial growth factor
6VEGFD-FLT4VEGFD_HUMAN - VGFR3_HUMANLigand-ReceptorSignaling by Vascular endothelial growth factor

II. Literature review

[source]
Namesprouting angiogenesis
IDGO_0002040
collection_id

Biological process

Description

The extension of new blood vessels from existing vessels into avascular tissues, this process includes the specialization of endothelial cells into leading tip and stalk cells, proliferation and migration of the endothelial cells and cell adhesion resulting in angiogenic sprout fusion or lumen formation.

External URL
Genes