Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| pericyte | 10 studies | 29% ± 13% | |
| smooth muscle cell | 9 studies | 34% ± 15% | |
| fibroblast | 7 studies | 23% ± 8% | |
| endothelial cell | 5 studies | 23% ± 5% | |
| endothelial cell of vascular tree | 4 studies | 24% ± 9% | |
| myofibroblast cell | 3 studies | 38% ± 18% | |
| extravillous trophoblast | 3 studies | 76% ± 15% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| placenta | 3 studies | 39% ± 22% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| thymus | 100% | 4921.85 | 653 / 653 | 98% | 47.75 | 591 / 605 |
| skin | 89% | 939.34 | 1608 / 1809 | 85% | 28.41 | 400 / 472 |
| uterus | 95% | 928.06 | 162 / 170 | 78% | 18.08 | 357 / 459 |
| bladder | 100% | 1183.86 | 21 / 21 | 73% | 11.71 | 366 / 504 |
| esophagus | 97% | 898.64 | 1404 / 1445 | 70% | 9.80 | 129 / 183 |
| breast | 98% | 1010.67 | 452 / 459 | 69% | 5.83 | 766 / 1118 |
| lung | 86% | 616.58 | 498 / 578 | 72% | 12.85 | 832 / 1155 |
| kidney | 92% | 604.92 | 82 / 89 | 65% | 57.72 | 586 / 901 |
| intestine | 87% | 636.00 | 840 / 966 | 60% | 5.60 | 315 / 527 |
| adrenal gland | 69% | 346.40 | 177 / 258 | 76% | 28.18 | 174 / 230 |
| brain | 54% | 264.93 | 1426 / 2642 | 85% | 21.71 | 601 / 705 |
| pancreas | 36% | 144.44 | 119 / 328 | 90% | 11.52 | 160 / 178 |
| prostate | 98% | 1703.18 | 240 / 245 | 21% | 1.49 | 105 / 502 |
| stomach | 51% | 285.46 | 184 / 359 | 64% | 6.28 | 182 / 286 |
| ureter | 0% | 0 | 0 / 0 | 100% | 5.02 | 1 / 1 |
| blood vessel | 100% | 3994.36 | 1329 / 1335 | 0% | 0 | 0 / 0 |
| adipose | 98% | 1004.12 | 1174 / 1204 | 0% | 0 | 0 / 0 |
| heart | 96% | 766.55 | 826 / 861 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 25.13 | 43 / 45 |
| liver | 49% | 189.23 | 110 / 226 | 39% | 3.58 | 157 / 406 |
| ovary | 54% | 452.91 | 97 / 180 | 27% | 2.36 | 118 / 430 |
| lymph node | 0% | 0 | 0 / 0 | 79% | 6.28 | 23 / 29 |
| muscle | 77% | 443.66 | 620 / 803 | 0% | 0 | 0 / 0 |
| spleen | 54% | 209.50 | 130 / 241 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 53% | 5.26 | 42 / 80 |
| peripheral blood | 8% | 34.80 | 76 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0051781 | Biological process | positive regulation of cell division |
| GO_0060754 | Biological process | positive regulation of mast cell chemotaxis |
| GO_0045766 | Biological process | positive regulation of angiogenesis |
| GO_0050918 | Biological process | positive chemotaxis |
| GO_0007165 | Biological process | signal transduction |
| GO_0001934 | Biological process | positive regulation of protein phosphorylation |
| GO_0038084 | Biological process | vascular endothelial growth factor signaling pathway |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_0002040 | Biological process | sprouting angiogenesis |
| GO_0001938 | Biological process | positive regulation of endothelial cell proliferation |
| GO_0030154 | Biological process | cell differentiation |
| GO_0001666 | Biological process | response to hypoxia |
| GO_0048010 | Biological process | vascular endothelial growth factor receptor signaling pathway |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0050930 | Biological process | induction of positive chemotaxis |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0016020 | Cellular component | membrane |
| GO_0008201 | Molecular function | heparin binding |
| GO_0008083 | Molecular function | growth factor activity |
| GO_0042056 | Molecular function | chemoattractant activity |
| GO_0005172 | Molecular function | vascular endothelial growth factor receptor binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PGF |
| Protein name | Placenta growth factor (PlGF) Placental growth factor (Placental growth factor, vascular endothelial growth factor-related protein, isoform CRA_a) Placental growth factor |
| Synonyms | PLGF PGFL hCG_22349 |
| Description | FUNCTION: Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Isoform PlGF-2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth. . |
| Accessions | Q53XY6 ENST00000553716.5 [P49763-2] P49763 ENST00000555567.6 [P49763-3] ENST00000405431.2 [P49763-1] ENST00000238607.10 G3XA84 |
