Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 4 studies | 45% ± 18% | |
capillary endothelial cell | 3 studies | 30% ± 8% | |
glomerular endothelial cell | 3 studies | 45% ± 13% |
Insufficient scRNA-seq data for expression of ESM1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 1531.75 | 89 / 89 | 86% | 215.10 | 777 / 901 |
lung | 100% | 1127.56 | 577 / 578 | 75% | 15.01 | 861 / 1155 |
adrenal gland | 83% | 154.85 | 215 / 258 | 90% | 54.00 | 208 / 230 |
thymus | 85% | 248.85 | 557 / 653 | 75% | 24.50 | 453 / 605 |
ovary | 59% | 59.54 | 107 / 180 | 69% | 8.83 | 296 / 430 |
breast | 41% | 37.26 | 186 / 459 | 80% | 14.28 | 899 / 1118 |
bladder | 38% | 34.00 | 8 / 21 | 71% | 14.29 | 358 / 504 |
pancreas | 33% | 21.16 | 107 / 328 | 76% | 17.35 | 136 / 178 |
uterus | 33% | 26.52 | 56 / 170 | 66% | 15.72 | 301 / 459 |
prostate | 73% | 167.37 | 178 / 245 | 22% | 4.04 | 110 / 502 |
stomach | 25% | 15.29 | 91 / 359 | 66% | 8.38 | 190 / 286 |
intestine | 21% | 19.67 | 202 / 966 | 68% | 10.50 | 356 / 527 |
liver | 21% | 11.57 | 48 / 226 | 62% | 12.67 | 252 / 406 |
skin | 32% | 121.93 | 585 / 1809 | 46% | 15.35 | 218 / 472 |
blood vessel | 77% | 170.91 | 1029 / 1335 | 0% | 0 | 0 / 0 |
esophagus | 15% | 8.07 | 213 / 1445 | 56% | 9.04 | 102 / 183 |
spleen | 69% | 60.36 | 167 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 58% | 7.99 | 26 / 45 |
adipose | 54% | 80.61 | 646 / 1204 | 0% | 0 | 0 / 0 |
heart | 47% | 93.25 | 401 / 861 | 0% | 0 | 0 / 0 |
brain | 13% | 24.00 | 343 / 2642 | 26% | 6.30 | 183 / 705 |
muscle | 15% | 7.25 | 122 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 5% | 0.47 | 4 / 80 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.22 | 1 / 29 |
peripheral blood | 3% | 1.79 | 28 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0008284 | Biological process | positive regulation of cell population proliferation |
GO_0001525 | Biological process | angiogenesis |
GO_1902204 | Biological process | positive regulation of hepatocyte growth factor receptor signaling pathway |
GO_0002040 | Biological process | sprouting angiogenesis |
GO_0005576 | Cellular component | extracellular region |
GO_0005171 | Molecular function | hepatocyte growth factor receptor binding |
GO_0005515 | Molecular function | protein binding |
GO_0005178 | Molecular function | integrin binding |
Gene name | ESM1 |
Protein name | Endothelial cell-specific molecule 1 (ESM-1) Endothelial cell specific molecule 1 |
Synonyms | |
Description | FUNCTION: Involved in angiogenesis; promotes angiogenic sprouting. May have potent implications in lung endothelial cell-leukocyte interactions. . |
Accessions | Q9NQ30 M0R154 ENST00000381403.4 [Q9NQ30-2] ENST00000601836.1 ENST00000381405.5 [Q9NQ30-1] |