DLG3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0009790Biological processembryo development
GO_0008285Biological processnegative regulation of cell population proliferation
GO_0097120Biological processreceptor localization to synapse
GO_0099072Biological processregulation of postsynaptic membrane neurotransmitter receptor levels
GO_0043113Biological processreceptor clustering
GO_0001736Biological processestablishment of planar polarity
GO_0007268Biological processchemical synaptic transmission
GO_0098609Biological processcell-cell adhesion
GO_0045197Biological processestablishment or maintenance of epithelial cell apical/basal polarity
GO_0061098Biological processpositive regulation of protein tyrosine kinase activity
GO_0098978Cellular componentglutamatergic synapse
GO_0005615Cellular componentextracellular space
GO_0098839Cellular componentpostsynaptic density membrane
GO_0005886Cellular componentplasma membrane
GO_0031594Cellular componentneuromuscular junction
GO_0032281Cellular componentAMPA glutamate receptor complex
GO_0043005Cellular componentneuron projection
GO_0005829Cellular componentcytosol
GO_0005912Cellular componentadherens junction
GO_0005923Cellular componentbicellular tight junction
GO_0016323Cellular componentbasolateral plasma membrane
GO_0019900Molecular functionkinase binding
GO_0019901Molecular functionprotein kinase binding
GO_0031625Molecular functionubiquitin protein ligase binding
GO_0019902Molecular functionphosphatase binding
GO_0035255Molecular functionionotropic glutamate receptor binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameDLG3
Protein nameDisks large homolog 3 (Neuroendocrine-DLG) (Synapse-associated protein 102) (SAP-102) (SAP102) (XLMR)
Discs large MAGUK scaffold protein 3 (Discs, large homolog 3 (Neuroendocrine-dlg, Drosophila), isoform CRA_b)
SynonymsKIAA1232
hCG_15353
DescriptionFUNCTION: Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling.

AccessionsENST00000374355.8 [Q92796-2]
Q5JUW8
ENST00000194900.8
Q92796
ENST00000542398.1 [Q92796-3]
ENST00000374360.8 [Q92796-1]