FRMD5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0031032Biological processactomyosin structure organization
GO_0030334Biological processregulation of cell migration
GO_0045785Biological processpositive regulation of cell adhesion
GO_2000146Biological processnegative regulation of cell motility
GO_0005856Cellular componentcytoskeleton
GO_0005912Cellular componentadherens junction
GO_0016020Cellular componentmembrane
GO_0019901Molecular functionprotein kinase binding
GO_0008092Molecular functioncytoskeletal protein binding
GO_0005515Molecular functionprotein binding
GO_0005178Molecular functionintegrin binding

IV. Literature review

[source]
Gene nameFRMD5
Protein nameFERM domain containing 5
FERM domain containing 5, isoform CRA_a (cDNA FLJ75251)
FERM domain-containing protein 5
SynonymshCG_1644657
DescriptionFUNCTION: May be involved in regulation of cell migration . May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation .

AccessionsF8WCI0
F8WEJ8
H7C282
H0YKW6
ENST00000449926.5
ENST00000636859.1
ENST00000421674.5
H0Y5N1
ENST00000558108.6
ENST00000458630.5
A0A087WVP2
Q7Z6J6
ENST00000618556.4
ENST00000451277.5
B5MC67
ENST00000484674.5
ENST00000417257.6 [Q7Z6J6-1]
ENST00000402883.5
H0YNI9
A0A1B0GV18
A8K1U8