Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| basal cell | 6 studies | 35% ± 17% | |
| keratinocyte | 5 studies | 44% ± 20% |
Insufficient scRNA-seq data for expression of PKP1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 43% | 5071.98 | 105 / 245 | 82% | 90.38 | 410 / 502 |
| esophagus | 38% | 36004.95 | 556 / 1445 | 66% | 523.87 | 121 / 183 |
| tonsil | 0% | 0 | 0 / 0 | 98% | 651.02 | 44 / 45 |
| skin | 72% | 120335.59 | 1302 / 1809 | 12% | 28.38 | 55 / 472 |
| uterus | 1% | 964.46 | 2 / 170 | 61% | 286.34 | 281 / 459 |
| lung | 3% | 325.07 | 17 / 578 | 47% | 229.85 | 538 / 1155 |
| bladder | 0% | 0 | 0 / 21 | 47% | 87.03 | 239 / 504 |
| breast | 12% | 1171.94 | 55 / 459 | 24% | 21.45 | 267 / 1118 |
| thymus | 0% | 0 | 0 / 653 | 15% | 36.31 | 93 / 605 |
| pancreas | 0% | 0 | 0 / 328 | 15% | 17.20 | 27 / 178 |
| intestine | 0% | 0 | 0 / 966 | 8% | 8.93 | 44 / 527 |
| stomach | 1% | 63.35 | 2 / 359 | 6% | 3.70 | 18 / 286 |
| adipose | 5% | 539.67 | 57 / 1204 | 0% | 0 | 0 / 0 |
| kidney | 0% | 0 | 0 / 89 | 3% | 1.63 | 26 / 901 |
| eye | 0% | 0 | 0 / 0 | 1% | 1.85 | 1 / 80 |
| ovary | 0% | 0 | 0 / 180 | 1% | 0.34 | 4 / 430 |
| adrenal gland | 0% | 0 | 0 / 258 | 1% | 0.36 | 2 / 230 |
| liver | 0% | 0 | 0 / 226 | 0% | 0.13 | 2 / 406 |
| blood vessel | 0% | 51.74 | 2 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 0% | 31.30 | 1 / 803 | 0% | 0 | 0 / 0 |
| brain | 0% | 2.89 | 1 / 2642 | 0% | 0 | 0 / 705 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 861 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0010628 | Biological process | positive regulation of gene expression |
| GO_0007155 | Biological process | cell adhesion |
| GO_0045110 | Biological process | intermediate filament bundle assembly |
| GO_1902373 | Biological process | negative regulation of mRNA catabolic process |
| GO_0098609 | Biological process | cell-cell adhesion |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005882 | Cellular component | intermediate filament |
| GO_0001533 | Cellular component | cornified envelope |
| GO_0005912 | Cellular component | adherens junction |
| GO_0101003 | Cellular component | ficolin-1-rich granule membrane |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0030057 | Cellular component | desmosome |
| GO_0005634 | Cellular component | nucleus |
| GO_0045296 | Molecular function | cadherin binding |
| GO_0005521 | Molecular function | lamin binding |
| GO_0030280 | Molecular function | structural constituent of skin epidermis |
| GO_0019215 | Molecular function | intermediate filament binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | PKP1 |
| Protein name | Plakophilin-1 (Band 6 protein) (B6P) PKP1 protein |
| Synonyms | |
| Description | FUNCTION: Seems to play a role in junctional plaques. Contributes to epidermal morphogenesis . May facilitate the formation of intermediate filaments . . |
| Accessions | ENST00000367324.8 [Q13835-2] Q13835 ENST00000352845.3 [Q13835-1] ENST00000263946.7 [Q13835-1] Q14BN3 |