intermediate filament

I. Literature review

[source]
Nameintermediate filament
IDGO_0005882
collection_id

Cellular component

Related synonym

intermediate filament associated protein, type I intermediate filament associated protein, type II intermediate filament associated protein

Description

A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.

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