KRTAP5-9 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KRTAP5-9 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KRTAP5-9 at tissue level.

III. Associated gene sets

GO_0008544Biological processepidermis development
GO_0005829Cellular componentcytosol
GO_0005882Cellular componentintermediate filament
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKRTAP5-9
Protein nameKeratin-associated protein 5-9 (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (Keratin-associated protein 5.9) (UHS keratin A) (UHS KerA) (Ultrahigh sulfur keratin-associated protein 5.9)
SynonymsKRN1
KAP5.9
UHSK1
KRTAP5.9
DescriptionFUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

AccessionsP26371
ENST00000528743.4