KRT2 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of KRT2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	82%	249093.87	1490 / 1809	9%	17.73	43 / 472
muscle	74%	158.40	592 / 803	0%	0	0 / 0
breast	67%	96.41	307 / 459	4%	0.28	48 / 1118
esophagus	61%	90.19	876 / 1445	10%	0.38	19 / 183
adipose	71%	245.79	850 / 1204	0%	0	0 / 0
blood vessel	66%	308.77	886 / 1335	0%	0	0 / 0
thymus	51%	90.91	330 / 653	14%	2.38	82 / 605
heart	63%	90.58	545 / 861	0%	0	0 / 0
prostate	45%	46.00	111 / 245	14%	0.27	70 / 502
lung	52%	121.70	303 / 578	5%	0.35	60 / 1155
peripheral blood	57%	77.77	530 / 929	0%	0	0 / 0
intestine	54%	80.23	518 / 966	2%	0.06	13 / 527
uterus	39%	56.46	67 / 170	11%	1.25	49 / 459
tonsil	0%	0	0 / 0	44%	3.61	20 / 45
ovary	43%	50.16	77 / 180	1%	0.02	5 / 430
brain	43%	63.46	1141 / 2642	0%	0.00	3 / 705
stomach	42%	54.37	149 / 359	2%	0.04	6 / 286
pancreas	42%	49.30	137 / 328	1%	0.03	2 / 178
liver	40%	64.18	90 / 226	0%	0.01	2 / 406
spleen	40%	45.54	96 / 241	0%	0	0 / 0
adrenal gland	38%	50.47	99 / 258	1%	0.37	3 / 230
kidney	33%	38.16	29 / 89	1%	0.02	10 / 901
lymph node	0%	0	0 / 0	14%	0.21	4 / 29
bladder	10%	7.10	2 / 21	4%	0.16	20 / 504
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0032980	Biological process	keratinocyte activation
GO_0018149	Biological process	peptide cross-linking
GO_0008544	Biological process	epidermis development
GO_0045684	Biological process	positive regulation of epidermis development
GO_0031424	Biological process	keratinization
GO_0051546	Biological process	keratinocyte migration
GO_0045109	Biological process	intermediate filament organization
GO_0003334	Biological process	keratinocyte development
GO_0043616	Biological process	keratinocyte proliferation
GO_0005615	Cellular component	extracellular space
GO_0016020	Cellular component	membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005882	Cellular component	intermediate filament
GO_0001533	Cellular component	cornified envelope
GO_0005829	Cellular component	cytosol
GO_0045095	Cellular component	keratin filament
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005200	Molecular function	structural constituent of cytoskeleton
GO_0030280	Molecular function	structural constituent of skin epidermis
GO_0008092	Molecular function	cytoskeletal protein binding
GO_0005515	Molecular function	protein binding

Gene name	KRT2
Protein name	Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Synonyms	KRT2E KRT2A
Description	FUNCTION: Probably contributes to terminal cornification . Associated with keratinocyte activation, proliferation and keratinization . Required for maintenance of corneocytes and keratin filaments in suprabasal keratinocytes in the epidermis of the ear, potentially via moderation of expression and localization of keratins and their partner proteins (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity). .
Accessions	P35908 ENST00000309680.4

KRT2 report