KRT10 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	35 studies	36% ± 13%	Explore
natural killer cell	35 studies	33% ± 11%	Explore
fibroblast	33 studies	38% ± 15%	Explore
CD8-positive, alpha-beta T cell	32 studies	35% ± 11%	Explore
endothelial cell	29 studies	37% ± 16%	Explore
CD4-positive, alpha-beta T cell	28 studies	35% ± 10%	Explore
T cell	27 studies	31% ± 9%	Explore
pericyte	23 studies	33% ± 12%	Explore
smooth muscle cell	22 studies	32% ± 10%	Explore
regulatory T cell	22 studies	33% ± 10%	Explore
basal cell	20 studies	45% ± 19%	Explore
naive B cell	19 studies	34% ± 9%	Explore
epithelial cell	19 studies	46% ± 19%	Explore
mast cell	18 studies	32% ± 8%	Explore
conventional dendritic cell	18 studies	28% ± 17%	Explore
memory B cell	18 studies	36% ± 10%	Explore
plasma cell	18 studies	45% ± 17%	Explore
plasmacytoid dendritic cell	18 studies	39% ± 12%	Explore
classical monocyte	18 studies	29% ± 13%	Explore
macrophage	17 studies	24% ± 8%	Explore
mature NK T cell	16 studies	33% ± 8%	Explore
ciliated cell	16 studies	48% ± 21%	Explore
connective tissue cell	16 studies	41% ± 16%	Explore
gamma-delta T cell	16 studies	36% ± 14%	Explore
endothelial cell of lymphatic vessel	15 studies	30% ± 9%	Explore
non-classical monocyte	14 studies	30% ± 15%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	13 studies	34% ± 10%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	13 studies	37% ± 13%	Explore
myofibroblast cell	13 studies	35% ± 12%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	35% ± 13%	Explore
CD16-positive, CD56-dim natural killer cell, human	12 studies	40% ± 10%	Explore
monocyte	12 studies	26% ± 8%	Explore
capillary endothelial cell	12 studies	28% ± 9%	Explore
mucosal invariant T cell	11 studies	33% ± 11%	Explore
secretory cell	11 studies	48% ± 19%	Explore
vein endothelial cell	11 studies	30% ± 9%	Explore
plasmablast	10 studies	50% ± 20%	Explore
CD4-positive, alpha-beta memory T cell	10 studies	34% ± 10%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	40% ± 14%	Explore
abnormal cell	10 studies	37% ± 16%	Explore
endothelial cell of artery	10 studies	37% ± 10%	Explore
endothelial cell of vascular tree	10 studies	33% ± 9%	Explore
dendritic cell	9 studies	38% ± 25%	Explore
goblet cell	8 studies	39% ± 15%	Explore
mesothelial cell	8 studies	48% ± 22%	Explore
T follicular helper cell	8 studies	39% ± 9%	Explore
type I pneumocyte	7 studies	31% ± 13%	Explore
club cell	7 studies	56% ± 13%	Explore
leukocyte	7 studies	34% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	7 studies	41% ± 15%	Explore
IgA plasma cell	7 studies	28% ± 8%	Explore
IgG plasma cell	7 studies	30% ± 12%	Explore
myeloid cell	7 studies	32% ± 15%	Explore
hematopoietic precursor cell	6 studies	34% ± 18%	Explore
respiratory goblet cell	6 studies	48% ± 21%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	35% ± 8%	Explore
epithelial cell of proximal tubule	6 studies	24% ± 5%	Explore
precursor B cell	6 studies	39% ± 6%	Explore
innate lymphoid cell	6 studies	35% ± 7%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	37% ± 15%	Explore
CD4-positive helper T cell	5 studies	27% ± 11%	Explore
exhausted T cell	5 studies	44% ± 13%	Explore
ionocyte	5 studies	40% ± 13%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	28% ± 6%	Explore
mononuclear phagocyte	5 studies	30% ± 14%	Explore
kidney loop of Henle epithelial cell	5 studies	34% ± 6%	Explore
progenitor cell	5 studies	33% ± 11%	Explore
enterocyte	5 studies	23% ± 5%	Explore
enteroendocrine cell	5 studies	42% ± 18%	Explore
intestinal crypt stem cell	5 studies	23% ± 8%	Explore
pro-B cell	5 studies	32% ± 3%	Explore
immature B cell	5 studies	42% ± 5%	Explore
neuron	5 studies	38% ± 18%	Explore
type II pneumocyte	5 studies	46% ± 13%	Explore
pancreatic A cell	4 studies	70% ± 17%	Explore
type B pancreatic cell	4 studies	71% ± 16%	Explore
transit amplifying cell	4 studies	25% ± 6%	Explore
hematopoietic stem cell	4 studies	20% ± 3%	Explore
brush cell	4 studies	41% ± 20%	Explore
adventitial cell	4 studies	40% ± 5%	Explore
mucus secreting cell	4 studies	39% ± 12%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	57% ± 7%	Explore
erythrocyte	4 studies	30% ± 7%	Explore
keratinocyte	4 studies	69% ± 23%	Explore
T-helper 17 cell	4 studies	37% ± 9%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	33% ± 12%	Explore
central memory CD8-positive, alpha-beta T cell	3 studies	19% ± 3%	Explore
deuterosomal cell	3 studies	49% ± 8%	Explore
duct epithelial cell	3 studies	55% ± 7%	Explore
pancreatic D cell	3 studies	79% ± 13%	Explore
glomerular endothelial cell	3 studies	25% ± 3%	Explore
podocyte	3 studies	32% ± 4%	Explore
kidney distal convoluted tubule epithelial cell	3 studies	26% ± 12%	Explore
renal alpha-intercalated cell	3 studies	32% ± 12%	Explore
neural crest cell	3 studies	38% ± 3%	Explore
extravillous trophoblast	3 studies	46% ± 9%	Explore
placental villous trophoblast	3 studies	25% ± 4%	Explore
lymphocyte	3 studies	40% ± 16%	Explore
neuroendocrine cell	3 studies	61% ± 19%	Explore
amacrine cell	3 studies	42% ± 13%	Explore
retina horizontal cell	3 studies	34% ± 17%	Explore
retinal cone cell	3 studies	54% ± 20%	Explore
retinal rod cell	3 studies	30% ± 12%	Explore
microglial cell	3 studies	31% ± 10%	Explore
serous secreting cell	3 studies	57% ± 7%	Explore
intraepithelial lymphocyte	3 studies	35% ± 7%	Explore
Mueller cell	3 studies	40% ± 8%	Explore
germinal center B cell	3 studies	34% ± 3%	Explore
intermediate monocyte	3 studies	46% ± 24%	Explore
myoepithelial cell	3 studies	33% ± 13%	Explore
luminal cell of prostate epithelium	3 studies	39% ± 10%	Explore
IgM plasma cell	3 studies	33% ± 8%	Explore
pancreatic ductal cell	3 studies	58% ± 11%	Explore
oligodendrocyte precursor cell	3 studies	34% ± 12%	Explore
granulocyte	3 studies	32% ± 7%	Explore
glial cell	3 studies	36% ± 19%	Explore
hepatocyte	3 studies	45% ± 30%	Explore
group 3 innate lymphoid cell	3 studies	37% ± 13%	Explore
melanocyte	3 studies	36% ± 3%	Explore
T-helper 1 cell	3 studies	39% ± 8%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	31% ± 12%	Explore
progenitor cell of mammary luminal epithelium	3 studies	32% ± 11%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	17 studies	39% ± 19%	Explore
peripheral blood	15 studies	38% ± 14%	Explore
intestine	10 studies	33% ± 14%	Explore
kidney	7 studies	27% ± 7%	Explore
eye	6 studies	31% ± 13%	Explore
lymph node	5 studies	38% ± 6%	Explore
brain	5 studies	28% ± 8%	Explore
liver	5 studies	32% ± 16%	Explore
pancreas	4 studies	65% ± 18%	Explore
bone marrow	4 studies	28% ± 6%	Explore
uterus	4 studies	47% ± 17%	Explore
breast	4 studies	36% ± 7%	Explore
placenta	3 studies	27% ± 6%	Explore
prostate	3 studies	37% ± 13%	Explore
skin	3 studies	48% ± 18%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	1815.48	1445 / 1445	100%	215.31	183 / 183
ovary	100%	1513.50	180 / 180	100%	59.53	430 / 430
uterus	100%	3115.13	170 / 170	100%	250.78	459 / 459
prostate	100%	1821.36	245 / 245	99%	40.76	499 / 502
brain	99%	1301.64	2626 / 2642	100%	43.51	705 / 705
pancreas	99%	1141.77	326 / 328	100%	38.07	178 / 178
skin	100%	872828.50	1809 / 1809	99%	415.38	469 / 472
stomach	100%	1319.00	359 / 359	99%	43.51	284 / 286
breast	100%	1799.59	459 / 459	99%	62.60	1104 / 1118
adrenal gland	100%	1362.81	258 / 258	98%	36.90	226 / 230
lung	99%	1403.33	571 / 578	99%	88.88	1147 / 1155
thymus	100%	1795.46	653 / 653	98%	35.93	593 / 605
bladder	100%	1443.67	21 / 21	98%	115.35	494 / 504
intestine	100%	1423.31	965 / 966	98%	43.01	517 / 527
kidney	100%	1455.38	89 / 89	96%	28.79	868 / 901
liver	98%	1078.60	222 / 226	96%	26.78	390 / 406
adipose	100%	2645.94	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	35.55	29 / 29
spleen	100%	1661.30	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	231.99	45 / 45
ureter	0%	0	0 / 0	100%	62.80	1 / 1
blood vessel	100%	2147.68	1332 / 1335	0%	0	0 / 0
heart	99%	1831.77	850 / 861	0%	0	0 / 0
muscle	98%	1249.67	786 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	89%	19.94	71 / 80
peripheral blood	84%	823.61	782 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0030216	Biological process	keratinocyte differentiation
GO_0018149	Biological process	peptide cross-linking
GO_0008544	Biological process	epidermis development
GO_0030855	Biological process	epithelial cell differentiation
GO_0045684	Biological process	positive regulation of epidermis development
GO_0045109	Biological process	intermediate filament organization
GO_0051290	Biological process	protein heterotetramerization
GO_0005615	Cellular component	extracellular space
GO_0005856	Cellular component	cytoskeleton
GO_0016020	Cellular component	membrane
GO_0070062	Cellular component	extracellular exosome
GO_0005882	Cellular component	intermediate filament
GO_0001533	Cellular component	cornified envelope
GO_0009986	Cellular component	cell surface
GO_0005829	Cellular component	cytosol
GO_0045095	Cellular component	keratin filament
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0030280	Molecular function	structural constituent of skin epidermis
GO_0046982	Molecular function	protein heterodimerization activity
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	KRT10
Protein name	Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10) Keratin, type I cytoskeletal 10 (Cytokeratin-10) (Keratin-10)
Synonyms	KPP
Description	FUNCTION: Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity). Involved in the maintenance of cell layer development and keratin filament bundles in suprabasal cells of the epithelium (By similarity). .; FUNCTION: (Microbial infection) Acts as a mediator of S.aureus adherence to desquamated nasal epithelial cells via clfB, and hence may play a role in nasal colonization. .; FUNCTION: (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Reduction of levels of KRT10 keratin decrease adherence, overexpression increases adherence. Neither protein has to be glycosylated for the interaction to occur. .
Accessions	ENST00000269576.6 ENST00000635956.2 P13645 A0A1B0GVI3

KRT10 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review