KRTAP5-8 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of KRTAP5-8 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of KRTAP5-8 at tissue level.

III. Associated gene sets

GO_0008150Biological processbiological_process
GO_0005829Cellular componentcytosol
GO_0005882Cellular componentintermediate filament
GO_0030280Molecular functionstructural constituent of skin epidermis
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameKRTAP5-8
Protein nameKeratin-associated protein 5-8 (Keratin, ultra high-sulfur matrix protein B) (Keratin-associated protein 5.8) (UHS keratin B) (UHS KerB) (Ultrahigh sulfur keratin-associated protein 5.8)
SynonymsKAP5.8
KRTAP5.8
UHSKB
DescriptionFUNCTION: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.

AccessionsENST00000398534.4
O75690