Insufficient scRNA-seq data for expression of ADORA2A at single-cell level.
Insufficient scRNA-seq data for expression of ADORA2A at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
liver | 99% | 636.18 | 224 / 226 | 39% | 0.71 | 159 / 406 |
kidney | 100% | 953.62 | 89 / 89 | 10% | 0.14 | 86 / 901 |
adrenal gland | 98% | 462.96 | 253 / 258 | 5% | 0.12 | 11 / 230 |
thymus | 98% | 461.03 | 640 / 653 | 5% | 0.08 | 29 / 605 |
bladder | 100% | 357.24 | 21 / 21 | 0% | 0.00 | 1 / 504 |
lung | 100% | 1375.64 | 577 / 578 | 0% | 0.01 | 4 / 1155 |
peripheral blood | 100% | 3340.79 | 929 / 929 | 0% | 0 | 0 / 0 |
spleen | 100% | 1435.06 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 99% | 598.55 | 856 / 861 | 0% | 0 | 0 / 0 |
prostate | 99% | 552.20 | 243 / 245 | 0% | 0 | 0 / 502 |
uterus | 98% | 427.22 | 167 / 170 | 0% | 0.01 | 2 / 459 |
brain | 98% | 2290.78 | 2582 / 2642 | 1% | 0.01 | 4 / 705 |
ovary | 98% | 376.77 | 176 / 180 | 0% | 0.00 | 1 / 430 |
intestine | 97% | 452.39 | 937 / 966 | 1% | 0.02 | 4 / 527 |
stomach | 88% | 287.20 | 316 / 359 | 1% | 0.03 | 4 / 286 |
blood vessel | 89% | 311.31 | 1185 / 1335 | 0% | 0 | 0 / 0 |
adipose | 84% | 265.58 | 1011 / 1204 | 0% | 0 | 0 / 0 |
breast | 81% | 255.96 | 373 / 459 | 2% | 0.05 | 27 / 1118 |
esophagus | 79% | 283.20 | 1143 / 1445 | 4% | 0.06 | 7 / 183 |
lymph node | 0% | 0 | 0 / 0 | 38% | 0.59 | 11 / 29 |
muscle | 37% | 86.64 | 296 / 803 | 0% | 0 | 0 / 0 |
skin | 34% | 72.27 | 613 / 1809 | 0% | 0 | 0 / 472 |
pancreas | 25% | 62.02 | 81 / 328 | 0% | 0 | 0 / 178 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0014061 | Biological process | regulation of norepinephrine secretion |
GO_0097190 | Biological process | apoptotic signaling pathway |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0014049 | Biological process | positive regulation of glutamate secretion |
GO_0007188 | Biological process | adenylate cyclase-modulating G protein-coupled receptor signaling pathway |
GO_0006954 | Biological process | inflammatory response |
GO_0051899 | Biological process | membrane depolarization |
GO_0051924 | Biological process | regulation of calcium ion transport |
GO_0048143 | Biological process | astrocyte activation |
GO_0060079 | Biological process | excitatory postsynaptic potential |
GO_0043116 | Biological process | negative regulation of vascular permeability |
GO_0001973 | Biological process | G protein-coupled adenosine receptor signaling pathway |
GO_0014074 | Biological process | response to purine-containing compound |
GO_0045938 | Biological process | positive regulation of circadian sleep/wake cycle, sleep |
GO_0007600 | Biological process | sensory perception |
GO_0007596 | Biological process | blood coagulation |
GO_0006968 | Biological process | cellular defense response |
GO_0007267 | Biological process | cell-cell signaling |
GO_0048812 | Biological process | neuron projection morphogenesis |
GO_0051881 | Biological process | regulation of mitochondrial membrane potential |
GO_0050714 | Biological process | positive regulation of protein secretion |
GO_0050728 | Biological process | negative regulation of inflammatory response |
GO_0099171 | Biological process | presynaptic modulation of chemical synaptic transmission |
GO_1900273 | Biological process | positive regulation of long-term synaptic potentiation |
GO_0042755 | Biological process | eating behavior |
GO_0008015 | Biological process | blood circulation |
GO_0006355 | Biological process | regulation of DNA-templated transcription |
GO_0007626 | Biological process | locomotory behavior |
GO_0006909 | Biological process | phagocytosis |
GO_0046636 | Biological process | negative regulation of alpha-beta T cell activation |
GO_0060080 | Biological process | inhibitory postsynaptic potential |
GO_0007189 | Biological process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
GO_0007417 | Biological process | central nervous system development |
GO_0001963 | Biological process | synaptic transmission, dopaminergic |
GO_0006915 | Biological process | apoptotic process |
GO_0051968 | Biological process | positive regulation of synaptic transmission, glutamatergic |
GO_0001975 | Biological process | response to amphetamine |
GO_2001235 | Biological process | positive regulation of apoptotic signaling pathway |
GO_0009410 | Biological process | response to xenobiotic stimulus |
GO_0042311 | Biological process | vasodilation |
GO_0031000 | Biological process | response to caffeine |
GO_0032230 | Biological process | positive regulation of synaptic transmission, GABAergic |
GO_0043524 | Biological process | negative regulation of neuron apoptotic process |
GO_0060134 | Biological process | prepulse inhibition |
GO_0007271 | Biological process | synaptic transmission, cholinergic |
GO_0035810 | Biological process | positive regulation of urine volume |
GO_0035249 | Biological process | synaptic transmission, glutamatergic |
GO_0007205 | Biological process | protein kinase C-activating G protein-coupled receptor signaling pathway |
GO_0014057 | Biological process | positive regulation of acetylcholine secretion, neurotransmission |
GO_0098978 | Cellular component | glutamatergic synapse |
GO_0005886 | Cellular component | plasma membrane |
GO_0016020 | Cellular component | membrane |
GO_0043025 | Cellular component | neuronal cell body |
GO_0042734 | Cellular component | presynaptic membrane |
GO_0005882 | Cellular component | intermediate filament |
GO_0030425 | Cellular component | dendrite |
GO_0030673 | Cellular component | axolemma |
GO_0048786 | Cellular component | presynaptic active zone |
GO_0032279 | Cellular component | asymmetric synapse |
GO_0045211 | Cellular component | postsynaptic membrane |
GO_0019899 | Molecular function | enzyme binding |
GO_0008289 | Molecular function | lipid binding |
GO_0044877 | Molecular function | protein-containing complex binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0051393 | Molecular function | alpha-actinin binding |
GO_0005516 | Molecular function | calmodulin binding |
GO_0005515 | Molecular function | protein binding |
GO_0001609 | Molecular function | G protein-coupled adenosine receptor activity |
GO_0031802 | Molecular function | type 5 metabotropic glutamate receptor binding |
Gene name | ADORA2A |
Protein name | Adenosine receptor A2a Adenosine A2a receptor Adenosine receptor A2 |
Synonyms | ADORA2 |
Description | FUNCTION: Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). . FUNCTION: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. . FUNCTION: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. . FUNCTION: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. . FUNCTION: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. . |
Accessions | ENST00000436735.1 S4R2Z8 ENST00000444262.6 S4R429 ENST00000618076.3 S4R3A7 P29274 ENST00000337539.12 C9J0Z4 ENST00000610595.4 C9JFS2 ENST00000472248.5 C9J3T2 ENST00000439591.1 C9JQD8 ENST00000496258.1 ENST00000486108.1 X5DNB4 ENST00000424232.5 ENST00000611543.4 |