synaptic transmission, cholinergic

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1CHAT+SLC5A7-CHRM3 - ACM3_HUMANLigand-ReceptorSignaling by Choline acetyltransferase
2CHAT+SLC5A7-CHRNA1+CHRNB1+CHRND+CHRNE - Ligand-ReceptorSignaling by Choline acetyltransferase
3CHAT+SLC5A7-CHRNA1+CHRNB1+CHRND+CHRNG - Ligand-ReceptorSignaling by Choline acetyltransferase
4CHAT+SLC5A7-CHRNA3+CHRNB4 - Ligand-ReceptorSignaling by Choline acetyltransferase
5CHAT+SLC5A7-CHRNA4+CHRNB2 - Ligand-ReceptorSignaling by Choline acetyltransferase
6CHAT+SLC5A7-CHRNA7 - Ligand-ReceptorSignaling by Choline acetyltransferase

II. Literature review

[source]
Namesynaptic transmission, cholinergic
IDGO_0007271
collection_id

Biological process

Exact synonym

cholinergic synaptic transmission

Description

The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.

External URL
Genes
CHRNA4CHRNDCHRNA2LYNX1ANXA9CHRNA5CHRNA1CHRNA6LYPD1CHRNGCHRNB3SLC5A7CHRNB2CHRNB4NQO1CHRNA3RIC3RAPSNADORA2ACHRNA7CHRNA10CHRNB1APOECHRM3CHRNE