CHRNB1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CHRNB1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHRNB1 at tissue level.

III. Associated gene sets

GO_0042391Biological processregulation of membrane potential
GO_0051899Biological processmembrane depolarization
GO_0055001Biological processmuscle cell development
GO_0060079Biological processexcitatory postsynaptic potential
GO_0007165Biological processsignal transduction
GO_0034220Biological processmonoatomic ion transmembrane transport
GO_0095500Biological processacetylcholine receptor signaling pathway
GO_0035095Biological processbehavioral response to nicotine
GO_0006936Biological processmuscle contraction
GO_0007274Biological processneuromuscular synaptic transmission
GO_0001941Biological processpostsynaptic membrane organization
GO_0007268Biological processchemical synaptic transmission
GO_0006812Biological processmonoatomic cation transport
GO_0007271Biological processsynaptic transmission, cholinergic
GO_0050877Biological processnervous system process
GO_0005886Cellular componentplasma membrane
GO_0031594Cellular componentneuromuscular junction
GO_0043005Cellular componentneuron projection
GO_0045202Cellular componentsynapse
GO_0099634Cellular componentpostsynaptic specialization membrane
GO_0005892Cellular componentacetylcholine-gated channel complex
GO_1904315Molecular functiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
GO_0015267Molecular functionchannel activity
GO_0015464Molecular functionacetylcholine receptor activity
GO_0015276Molecular functionligand-gated monoatomic ion channel activity
GO_0042166Molecular functionacetylcholine binding
GO_0022848Molecular functionacetylcholine-gated monoatomic cation-selective channel activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCHRNB1
Protein nameCholinergic receptor nicotinic beta 1 subunit
Acetylcholine receptor subunit beta
SynonymsACHRB
CHRNB
DescriptionFUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .

FUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .

FUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .

FUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .

AccessionsENST00000639993.1 [P11230-2]
ENST00000575379.1
I3L1T7
P11230
ENST00000536404.6 [P11230-2]
ENST00000570557.5
ENST00000576360.1
ENST00000639692.2 [P11230-1]
I3L535
I3L3Q9
ENST00000306071.7 [P11230-1]
ENST00000572857.5
I3L4N5