ANXA9 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ANXA9 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ANXA9 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
liver	100%	1004.92	226 / 226	98%	100.46	399 / 406
pancreas	100%	1124.55	328 / 328	95%	44.37	169 / 178
kidney	100%	919.40	89 / 89	87%	22.54	788 / 901
thymus	100%	908.94	652 / 653	87%	53.15	524 / 605
breast	83%	281.71	379 / 459	93%	100.61	1038 / 1118
intestine	93%	189.89	900 / 966	81%	18.49	429 / 527
brain	74%	169.35	1957 / 2642	96%	22.65	674 / 705
stomach	92%	197.29	330 / 359	77%	18.75	221 / 286
ovary	98%	281.59	176 / 180	70%	18.28	301 / 430
bladder	86%	318.81	18 / 21	82%	50.36	411 / 504
prostate	90%	205.49	220 / 245	75%	12.23	374 / 502
uterus	100%	413.57	170 / 170	64%	22.40	294 / 459
esophagus	92%	526.78	1333 / 1445	51%	15.09	93 / 183
skin	73%	1484.72	1327 / 1809	66%	13.52	313 / 472
lung	73%	142.18	421 / 578	63%	13.17	722 / 1155
adrenal gland	82%	157.99	211 / 258	49%	7.97	113 / 230
ureter	0%	0	0 / 0	100%	83.92	1 / 1
spleen	90%	180.74	218 / 241	0%	0	0 / 0
adipose	71%	202.92	857 / 1204	0%	0	0 / 0
heart	67%	121.75	576 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	49%	11.26	22 / 45
peripheral blood	48%	176.90	446 / 929	0%	0	0 / 0
blood vessel	41%	61.12	551 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	34%	4.07	27 / 80
muscle	12%	16.34	96 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	3%	0.34	1 / 29
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0098609	Biological process	cell-cell adhesion
GO_0007271	Biological process	synaptic transmission, cholinergic
GO_0009986	Cellular component	cell surface
GO_0005829	Cellular component	cytosol
GO_0005886	Cellular component	plasma membrane
GO_0045202	Cellular component	synapse
GO_0012506	Cellular component	vesicle membrane
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0015464	Molecular function	acetylcholine receptor activity
GO_0005509	Molecular function	calcium ion binding
GO_0001786	Molecular function	phosphatidylserine binding
GO_0005515	Molecular function	protein binding
GO_0005544	Molecular function	calcium-dependent phospholipid binding
GO_0005543	Molecular function	phospholipid binding

IV. Literature review

Gene name	ANXA9
Protein name	Annexin A9 (Annexin XXXI) (Annexin-31) (Annexin-9) (Pemphaxin)
Synonyms	ANX31
Description	FUNCTION: Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes. .
Accessions	O76027 ENST00000368947.9