CHRNE | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHRNE at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
ovary	96%	96.63	173 / 180	60%	1.41	256 / 430
kidney	94%	93.38	84 / 89	57%	1.02	510 / 901
liver	100%	220.75	226 / 226	47%	1.05	191 / 406
thymus	93%	101.75	605 / 653	46%	0.94	277 / 605
breast	99%	130.59	455 / 459	30%	0.58	331 / 1118
skin	88%	187.94	1600 / 1809	39%	1.54	183 / 472
pancreas	100%	153.23	328 / 328	27%	0.54	48 / 178
lung	94%	115.48	544 / 578	30%	0.62	345 / 1155
prostate	92%	70.78	225 / 245	9%	0.12	45 / 502
spleen	100%	195.07	241 / 241	0%	0	0 / 0
uterus	82%	56.46	139 / 170	15%	0.32	70 / 459
adipose	96%	134.12	1152 / 1204	0%	0	0 / 0
stomach	75%	49.69	271 / 359	11%	0.25	32 / 286
peripheral blood	82%	164.58	766 / 929	0%	0	0 / 0
blood vessel	79%	74.63	1051 / 1335	0%	0	0 / 0
brain	60%	38.92	1575 / 2642	19%	0.30	131 / 705
adrenal gland	51%	41.47	131 / 258	23%	0.52	53 / 230
heart	72%	1752.05	616 / 861	0%	0	0 / 0
intestine	59%	44.18	570 / 966	9%	0.17	47 / 527
eye	0%	0	0 / 0	65%	2.18	52 / 80
esophagus	47%	31.23	679 / 1445	17%	0.37	32 / 183
bladder	52%	32.90	11 / 21	11%	0.24	57 / 504
muscle	50%	77.18	398 / 803	0%	0	0 / 0
lymph node	0%	0	0 / 0	41%	0.65	12 / 29
tonsil	0%	0	0 / 0	13%	0.18	6 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0051899	Biological process	membrane depolarization
GO_0060079	Biological process	excitatory postsynaptic potential
GO_0007165	Biological process	signal transduction
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0095500	Biological process	acetylcholine receptor signaling pathway
GO_0006936	Biological process	muscle contraction
GO_0007268	Biological process	chemical synaptic transmission
GO_0098655	Biological process	monoatomic cation transmembrane transport
GO_0007271	Biological process	synaptic transmission, cholinergic
GO_0005886	Cellular component	plasma membrane
GO_0031594	Cellular component	neuromuscular junction
GO_0043005	Cellular component	neuron projection
GO_0045202	Cellular component	synapse
GO_0045211	Cellular component	postsynaptic membrane
GO_0005892	Cellular component	acetylcholine-gated channel complex
GO_1904315	Molecular function	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
GO_0015464	Molecular function	acetylcholine receptor activity
GO_0008324	Molecular function	monoatomic cation transmembrane transporter activity
GO_0022848	Molecular function	acetylcholine-gated monoatomic cation-selective channel activity

Gene name	CHRNE
Protein name	Cholinergic receptor nicotinic epsilon subunit Acetylcholine receptor subunit epsilon AchR epsilon subunit
Synonyms	ACHRE
Description	FUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .
Accessions	ENST00000649830.1 Q04844 A0A3B3IRM1 Q8N731 ENST00000649488.2

CHRNE report