CHRNA2 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHRNA2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	92%	3391.43	226 / 245	99%	96.09	498 / 502
brain	75%	235.51	1990 / 2642	23%	0.72	165 / 705
adrenal gland	73%	109.72	189 / 258	16%	1.72	36 / 230
peripheral blood	50%	29.24	468 / 929	0%	0	0 / 0
lung	42%	21.41	244 / 578	1%	0.02	7 / 1155
skin	37%	24.40	672 / 1809	0%	0.01	2 / 472
breast	29%	89.47	133 / 459	3%	0.13	38 / 1118
spleen	31%	9.70	75 / 241	0%	0	0 / 0
pancreas	15%	3.99	49 / 328	1%	0.03	1 / 178
thymus	7%	2.05	47 / 653	7%	0.25	40 / 605
liver	4%	2.38	10 / 226	1%	0.02	3 / 406
tonsil	0%	0	0 / 0	4%	1.04	2 / 45
stomach	3%	0.67	9 / 359	1%	0.05	2 / 286
esophagus	2%	0.66	36 / 1445	1%	0.01	1 / 183
eye	0%	0	0 / 0	3%	0.15	2 / 80
intestine	2%	0.56	18 / 966	0%	0.01	2 / 527
adipose	2%	0.94	27 / 1204	0%	0	0 / 0
bladder	0%	0	0 / 21	1%	0.15	4 / 504
blood vessel	1%	0.68	8 / 1335	0%	0	0 / 0
ovary	1%	0.56	1 / 180	0%	0	0 / 430
kidney	0%	0	0 / 89	1%	0.01	5 / 901
muscle	0%	0.11	2 / 803	0%	0	0 / 0
uterus	0%	0	0 / 170	0%	0.00	1 / 459
heart	0%	0.02	1 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0051899	Biological process	membrane depolarization
GO_0098828	Biological process	modulation of inhibitory postsynaptic potential
GO_0060079	Biological process	excitatory postsynaptic potential
GO_0007165	Biological process	signal transduction
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0006811	Biological process	monoatomic ion transport
GO_0095500	Biological process	acetylcholine receptor signaling pathway
GO_0035094	Biological process	response to nicotine
GO_0071316	Biological process	cellular response to nicotine
GO_0007271	Biological process	synaptic transmission, cholinergic
GO_0120111	Cellular component	neuron projection cytoplasm
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0005654	Cellular component	nucleoplasm
GO_0043005	Cellular component	neuron projection
GO_0045171	Cellular component	intercellular bridge
GO_0045202	Cellular component	synapse
GO_0045211	Cellular component	postsynaptic membrane
GO_0005892	Cellular component	acetylcholine-gated channel complex
GO_1901363	Molecular function	heterocyclic compound binding
GO_0015464	Molecular function	acetylcholine receptor activity
GO_0022848	Molecular function	acetylcholine-gated monoatomic cation-selective channel activity
GO_0050997	Molecular function	quaternary ammonium group binding

Gene name	CHRNA2
Protein name	Neuronal acetylcholine receptor subunit alpha-2 Cholinergic receptor nicotinic alpha 2 subunit
Synonyms
Description	FUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. FUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. . FUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .
Accessions	E5RHQ4 ENST00000518712.5 ENST00000524096.5 A0A0X1KG79 Q15822 ENST00000521921.5 E5RGT4 E5RK67 ENST00000520208.1 ENST00000240132.7 [Q15822-2] ENST00000523695.5 ENST00000407991.3 [Q15822-1] ENST00000520933.7 E5RGP6 ENST00000637241.1 E5RJ54 A0A1B0GVX5

CHRNA2 report