CHRNA6 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHRNA6 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	66%	34.24	1744 / 2642	10%	0.23	73 / 705
adrenal gland	55%	9.17	141 / 258	8%	0.97	19 / 230
skin	8%	0.47	141 / 1809	43%	4.74	203 / 472
thymus	42%	3.68	272 / 653	6%	0.12	35 / 605
pancreas	40%	3.26	132 / 328	6%	0.08	10 / 178
breast	4%	0.20	19 / 459	41%	1.67	457 / 1118
kidney	15%	0.97	13 / 89	23%	0.52	205 / 901
spleen	32%	2.12	77 / 241	0%	0	0 / 0
lung	22%	1.62	128 / 578	7%	2.51	79 / 1155
ovary	14%	2.10	25 / 180	14%	0.27	60 / 430
lymph node	0%	0	0 / 0	28%	1.24	8 / 29
uterus	21%	2.41	35 / 170	3%	0.08	14 / 459
peripheral blood	21%	31.61	197 / 929	0%	0	0 / 0
tonsil	0%	0	0 / 0	20%	1.95	9 / 45
blood vessel	17%	1.29	226 / 1335	0%	0	0 / 0
prostate	14%	0.91	34 / 245	0%	0.01	1 / 502
intestine	9%	0.65	88 / 966	2%	0.07	8 / 527
esophagus	5%	0.25	66 / 1445	5%	0.11	9 / 183
bladder	5%	0.19	1 / 21	3%	0.33	13 / 504
heart	7%	0.85	63 / 861	0%	0	0 / 0
stomach	2%	0.12	8 / 359	4%	0.06	11 / 286
liver	4%	0.20	9 / 226	1%	0.02	5 / 406
adipose	4%	0.25	50 / 1204	0%	0	0 / 0
muscle	2%	0.14	20 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	1%	0.07	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0014059	Biological process	regulation of dopamine secretion
GO_0051899	Biological process	membrane depolarization
GO_0060079	Biological process	excitatory postsynaptic potential
GO_0007165	Biological process	signal transduction
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0095500	Biological process	acetylcholine receptor signaling pathway
GO_0007268	Biological process	chemical synaptic transmission
GO_0099171	Biological process	presynaptic modulation of chemical synaptic transmission
GO_0035094	Biological process	response to nicotine
GO_0007271	Biological process	synaptic transmission, cholinergic
GO_0005886	Cellular component	plasma membrane
GO_0098691	Cellular component	dopaminergic synapse
GO_0043005	Cellular component	neuron projection
GO_0042734	Cellular component	presynaptic membrane
GO_0045202	Cellular component	synapse
GO_0045211	Cellular component	postsynaptic membrane
GO_0005892	Cellular component	acetylcholine-gated channel complex
GO_0015464	Molecular function	acetylcholine receptor activity
GO_0022848	Molecular function	acetylcholine-gated monoatomic cation-selective channel activity
GO_0005515	Molecular function	protein binding

Gene name	CHRNA6
Protein name	Cholinergic receptor nicotinic alpha 6 subunit Alternative protein CHRNA6 Neuronal acetylcholine receptor subunit alpha-6
Synonyms
Description	FUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. FUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .
Accessions	Q15825 ENST00000534622.5 [Q15825-2] ENST00000276410.7 [Q15825-1] L8ECB0 ENST00000533810.5 E9PP97

CHRNA6 report