CHRNB3 | OmnibusX

Name	Number of supported studies	Average coverage
retinal ganglion cell	3 studies	20% ± 5%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHRNB3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	95%	55.41	313 / 328	2%	0.03	3 / 178
brain	49%	43.58	1284 / 2642	3%	0.04	21 / 705
uterus	5%	0.96	8 / 170	0%	0.01	2 / 459
ovary	2%	0.21	4 / 180	1%	0.02	5 / 430
lung	2%	0.30	14 / 578	1%	0.01	7 / 1155
adrenal gland	1%	3.09	2 / 258	1%	0.05	2 / 230
eye	0%	0	0 / 0	1%	0.10	1 / 80
stomach	0%	0	0 / 359	1%	0.02	3 / 286
liver	0%	0	0 / 226	1%	0.06	4 / 406
blood vessel	1%	0.14	11 / 1335	0%	0	0 / 0
breast	0%	0	0 / 459	1%	0.02	8 / 1118
esophagus	0%	0.01	2 / 1445	1%	0.02	1 / 183
skin	0%	0.03	5 / 1809	0%	0.00	1 / 472
heart	0%	0.07	4 / 861	0%	0	0 / 0
bladder	0%	0	0 / 21	0%	0.01	2 / 504
peripheral blood	0%	0.04	3 / 929	0%	0	0 / 0
intestine	0%	0	0 / 966	0%	0.00	1 / 527
thymus	0%	0	0 / 653	0%	0.01	1 / 605
muscle	0%	0.01	1 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
adipose	0%	0	0 / 1204	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
kidney	0%	0	0 / 89	0%	0	0 / 901
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
prostate	0%	0	0 / 245	0%	0	0 / 502
spinal column	0%	0	0 / 0	0%	0	0 / 0
spleen	0%	0	0 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0051899	Biological process	membrane depolarization
GO_0060079	Biological process	excitatory postsynaptic potential
GO_0007165	Biological process	signal transduction
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0095500	Biological process	acetylcholine receptor signaling pathway
GO_0099171	Biological process	presynaptic modulation of chemical synaptic transmission
GO_0035094	Biological process	response to nicotine
GO_0007271	Biological process	synaptic transmission, cholinergic
GO_0098793	Cellular component	presynapse
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0098691	Cellular component	dopaminergic synapse
GO_0043005	Cellular component	neuron projection
GO_0045202	Cellular component	synapse
GO_0045211	Cellular component	postsynaptic membrane
GO_0005892	Cellular component	acetylcholine-gated channel complex
GO_1901363	Molecular function	heterocyclic compound binding
GO_0015267	Molecular function	channel activity
GO_0015464	Molecular function	acetylcholine receptor activity
GO_0042166	Molecular function	acetylcholine binding
GO_0022848	Molecular function	acetylcholine-gated monoatomic cation-selective channel activity

Gene name	CHRNB3
Protein name	Cholinergic receptor nicotinic beta 3 subunit Neuronal acetylcholine receptor subunit beta-3
Synonyms
Description	FUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Accessions	Q05901 A0A1D5RMT8 ENST00000289957.3 ENST00000534391.1

CHRNB3 report