RAPSN | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of RAPSN at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	99%	122.70	255 / 258	19%	1.07	44 / 230
lung	91%	48.95	527 / 578	14%	0.51	156 / 1155
intestine	96%	57.03	924 / 966	6%	0.09	34 / 527
muscle	100%	2921.43	803 / 803	0%	0	0 / 0
spleen	100%	73.55	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	3.80	1 / 1
liver	85%	27.89	191 / 226	13%	0.33	52 / 406
kidney	84%	26.82	75 / 89	9%	0.17	78 / 901
breast	73%	23.59	333 / 459	8%	0.51	91 / 1118
prostate	64%	36.23	157 / 245	11%	0.38	53 / 502
thymus	70%	19.97	458 / 653	3%	0.09	21 / 605
heart	72%	68.33	619 / 861	0%	0	0 / 0
adipose	70%	25.31	837 / 1204	0%	0	0 / 0
skin	63%	29.16	1143 / 1809	4%	0.25	19 / 472
esophagus	48%	12.50	688 / 1445	18%	0.36	33 / 183
peripheral blood	63%	51.19	589 / 929	0%	0	0 / 0
stomach	51%	13.73	183 / 359	9%	0.17	26 / 286
brain	46%	12.97	1217 / 2642	11%	0.36	79 / 705
pancreas	30%	6.85	100 / 328	16%	0.29	28 / 178
bladder	19%	4.86	4 / 21	25%	1.18	128 / 504
ovary	9%	1.65	16 / 180	26%	1.44	111 / 430
uterus	12%	3.01	21 / 170	20%	9.68	93 / 459
blood vessel	15%	4.54	206 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	13%	0.53	6 / 45
lymph node	0%	0	0 / 0	10%	0.14	3 / 29
eye	0%	0	0 / 0	1%	0.01	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0071340	Biological process	skeletal muscle acetylcholine-gated channel clustering
GO_1900075	Biological process	positive regulation of neuromuscular synaptic transmission
GO_1901626	Biological process	regulation of postsynaptic membrane organization
GO_2000673	Biological process	positive regulation of motor neuron apoptotic process
GO_0007268	Biological process	chemical synaptic transmission
GO_1903540	Biological process	establishment of protein localization to postsynaptic membrane
GO_0097049	Biological process	motor neuron apoptotic process
GO_0098880	Biological process	maintenance of postsynaptic specialization structure
GO_0099645	Biological process	neurotransmitter receptor localization to postsynaptic specialization membrane
GO_0007271	Biological process	synaptic transmission, cholinergic
GO_0005886	Cellular component	plasma membrane
GO_0031594	Cellular component	neuromuscular junction
GO_0005813	Cellular component	centrosome
GO_0005794	Cellular component	Golgi apparatus
GO_0005829	Cellular component	cytosol
GO_0099634	Cellular component	postsynaptic specialization membrane
GO_0098879	Molecular function	structural constituent of postsynaptic specialization
GO_0043495	Molecular function	protein-membrane adaptor activity
GO_0046872	Molecular function	metal ion binding
GO_0035255	Molecular function	ionotropic glutamate receptor binding
GO_0033130	Molecular function	acetylcholine receptor binding

Gene name	RAPSN
Protein name	Receptor-associated protein of the synapse isoform 3 Receptor-associated protein of the synapse isoform 2 Receptor-associated protein of the synapse isoform 5 Receptor-associated protein of the synapse isoform 4 43 kDa receptor-associated protein of the synapse (RAPsyn) (43 kDa postsynaptic protein) (Acetylcholine receptor-associated 43 kDa protein) (RING finger protein 205) Receptor associated protein of the synapse Receptor-associated protein of the synapse isoform 1 (Receptor-associated protein of the synapse, 43kD, isoform CRA_b) Alternative protein RAPSN
Synonyms	RNF205 hCG_25182
Description	FUNCTION: Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin.
Accessions	ENST00000352508.7 [Q13702-2] A0A0S2Z4F7 A0A0S2Z4A6 E9PJP9 A0A0S2Z4F8 Q13702 ENST00000524487.5 ENST00000529341.1 L8EBB2 A0A0S2Z4M9 E9PK11 A0A0S2Z4A2 ENST00000298854.7 [Q13702-1]

RAPSN report