CHRNA5 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of CHRNA5 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
intestine	100%	82.41	965 / 966	86%	2.37	452 / 527
bladder	100%	39.76	21 / 21	84%	2.54	423 / 504
esophagus	96%	33.63	1391 / 1445	85%	2.77	156 / 183
stomach	89%	28.96	321 / 359	86%	2.30	247 / 286
uterus	98%	39.12	166 / 170	75%	2.16	346 / 459
pancreas	98%	30.11	322 / 328	72%	2.11	129 / 178
prostate	95%	42.11	233 / 245	67%	1.77	334 / 502
adrenal gland	86%	43.89	221 / 258	72%	11.01	166 / 230
skin	89%	31.11	1609 / 1809	53%	1.16	252 / 472
lung	74%	16.83	427 / 578	63%	1.88	731 / 1155
ovary	87%	21.29	156 / 180	46%	1.08	197 / 430
breast	89%	22.32	410 / 459	33%	0.88	365 / 1118
ureter	0%	0	0 / 0	100%	3.31	1 / 1
brain	87%	23.96	2301 / 2642	12%	0.20	82 / 705
muscle	93%	35.70	749 / 803	0%	0	0 / 0
heart	87%	25.19	751 / 861	0%	0	0 / 0
adipose	83%	20.50	998 / 1204	0%	0	0 / 0
thymus	63%	10.79	409 / 653	11%	0.25	64 / 605
spleen	64%	8.83	155 / 241	0%	0	0 / 0
blood vessel	62%	10.50	827 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	51%	1.19	23 / 45
kidney	45%	7.51	40 / 89	6%	0.12	51 / 901
lymph node	0%	0	0 / 0	41%	0.75	12 / 29
peripheral blood	38%	43.97	355 / 929	0%	0	0 / 0
liver	27%	3.14	61 / 226	6%	0.14	26 / 406
eye	0%	0	0 / 0	3%	0.03	2 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0051899	Biological process	membrane depolarization
GO_0060079	Biological process	excitatory postsynaptic potential
GO_0007165	Biological process	signal transduction
GO_0034220	Biological process	monoatomic ion transmembrane transport
GO_0095500	Biological process	acetylcholine receptor signaling pathway
GO_0035095	Biological process	behavioral response to nicotine
GO_0007268	Biological process	chemical synaptic transmission
GO_0099171	Biological process	presynaptic modulation of chemical synaptic transmission
GO_0035094	Biological process	response to nicotine
GO_0007271	Biological process	synaptic transmission, cholinergic
GO_0098793	Cellular component	presynapse
GO_0005886	Cellular component	plasma membrane
GO_0098691	Cellular component	dopaminergic synapse
GO_0043005	Cellular component	neuron projection
GO_0045202	Cellular component	synapse
GO_0045211	Cellular component	postsynaptic membrane
GO_0005892	Cellular component	acetylcholine-gated channel complex
GO_0015464	Molecular function	acetylcholine receptor activity
GO_0015276	Molecular function	ligand-gated monoatomic ion channel activity
GO_0022848	Molecular function	acetylcholine-gated monoatomic cation-selective channel activity
GO_0005515	Molecular function	protein binding

Gene name	CHRNA5
Protein name	Neuronal nicotinic acetylcholine receptor, alpha5 subunit Neuronal acetylcholine receptor subunit alpha-5 Cholinergic receptor nicotinic alpha 5 subunit (Cholinergic receptor, nicotinic, alpha 5, isoform CRA_b) Cholinergic receptor nicotinic alpha 5 subunit
Synonyms	NACHRA5 hCG_95858
Description	FUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. FUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. . FUNCTION: After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. .
Accessions	ENST00000559554.5 P30532 Q6EWN4 ENST00000394802.4 H0YM98 H0YK34 ENST00000559576.1 ENST00000299565.9 H7BYM0

CHRNA5 report