Name | Number of supported studies | Average coverage | |
---|---|---|---|
B cell | 14 studies | 21% ± 4% | |
memory B cell | 14 studies | 21% ± 4% | |
astrocyte | 9 studies | 34% ± 17% | |
oligodendrocyte precursor cell | 9 studies | 36% ± 17% | |
glutamatergic neuron | 8 studies | 47% ± 28% | |
retinal rod cell | 8 studies | 29% ± 7% | |
amacrine cell | 7 studies | 34% ± 12% | |
GABAergic neuron | 7 studies | 44% ± 24% | |
interneuron | 6 studies | 40% ± 23% | |
naive B cell | 6 studies | 19% ± 2% | |
retinal cone cell | 6 studies | 32% ± 12% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 6 studies | 17% ± 2% | |
neuron | 5 studies | 34% ± 13% | |
retina horizontal cell | 5 studies | 23% ± 7% | |
basal cell | 4 studies | 26% ± 14% | |
endothelial cell | 4 studies | 32% ± 10% | |
retinal bipolar neuron | 4 studies | 41% ± 8% | |
retinal ganglion cell | 4 studies | 32% ± 11% | |
type I pneumocyte | 4 studies | 20% ± 3% | |
type II pneumocyte | 4 studies | 19% ± 2% | |
oligodendrocyte | 4 studies | 28% ± 8% | |
naive thymus-derived CD8-positive, alpha-beta T cell | 4 studies | 18% ± 1% | |
pancreatic A cell | 3 studies | 26% ± 8% | |
retinal pigment epithelial cell | 3 studies | 39% ± 14% | |
cardiac muscle cell | 3 studies | 27% ± 2% | |
mesothelial cell | 3 studies | 21% ± 3% | |
Mueller cell | 3 studies | 24% ± 7% | |
rod bipolar cell | 3 studies | 38% ± 2% | |
T follicular helper cell | 3 studies | 19% ± 4% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 100% | 2962.95 | 2631 / 2642 | 98% | 13.70 | 694 / 705 |
thymus | 100% | 5011.52 | 653 / 653 | 96% | 10.08 | 582 / 605 |
adrenal gland | 100% | 2470.96 | 258 / 258 | 94% | 10.97 | 217 / 230 |
prostate | 100% | 3954.18 | 245 / 245 | 86% | 5.75 | 431 / 502 |
ovary | 100% | 3457.76 | 180 / 180 | 50% | 3.44 | 213 / 430 |
kidney | 100% | 1964.13 | 89 / 89 | 47% | 2.77 | 423 / 901 |
pancreas | 100% | 1972.79 | 328 / 328 | 39% | 1.92 | 69 / 178 |
esophagus | 99% | 1823.36 | 1431 / 1445 | 15% | 0.52 | 27 / 183 |
uterus | 99% | 2320.69 | 169 / 170 | 14% | 0.55 | 63 / 459 |
bladder | 100% | 2033.05 | 21 / 21 | 12% | 0.63 | 60 / 504 |
breast | 78% | 1315.39 | 359 / 459 | 28% | 1.68 | 318 / 1118 |
lung | 81% | 729.90 | 467 / 578 | 22% | 0.91 | 254 / 1155 |
stomach | 96% | 1318.43 | 344 / 359 | 7% | 0.25 | 19 / 286 |
spleen | 100% | 1718.28 | 241 / 241 | 0% | 0 | 0 / 0 |
heart | 90% | 1087.82 | 775 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 89% | 790.00 | 1183 / 1335 | 0% | 0 | 0 / 0 |
intestine | 84% | 1641.80 | 815 / 966 | 4% | 0.21 | 21 / 527 |
skin | 72% | 1714.67 | 1304 / 1809 | 7% | 0.38 | 34 / 472 |
muscle | 72% | 518.28 | 579 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 52% | 2.23 | 15 / 29 |
liver | 39% | 235.35 | 89 / 226 | 6% | 0.22 | 23 / 406 |
adipose | 42% | 330.86 | 510 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 33% | 1.82 | 26 / 80 |
tonsil | 0% | 0 | 0 / 0 | 22% | 1.00 | 10 / 45 |
peripheral blood | 19% | 130.43 | 177 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006457 | Biological process | protein folding |
GO_0007204 | Biological process | positive regulation of cytosolic calcium ion concentration |
GO_0007271 | Biological process | synaptic transmission, cholinergic |
GO_0034394 | Biological process | protein localization to cell surface |
GO_2000010 | Biological process | positive regulation of protein localization to cell surface |
GO_0065003 | Biological process | protein-containing complex assembly |
GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
GO_0000139 | Cellular component | Golgi membrane |
GO_0045202 | Cellular component | synapse |
GO_0043025 | Cellular component | neuronal cell body |
GO_0043005 | Cellular component | neuron projection |
GO_0005789 | Cellular component | endoplasmic reticulum membrane |
GO_0044183 | Molecular function | protein folding chaperone |
GO_0033130 | Molecular function | acetylcholine receptor binding |
Gene name | RIC3 |
Protein name | Resistance to inhibitors of cholinesterase 3-like protein isoform 4 Protein RIC-3 (Resistant to inhibitor of cholinesterase 3) RIC3 acetylcholine receptor chaperone Resistance to inhibitors of cholinesterase 3-like protein isoform 1 Resistance to inhibitors of cholinesterase 3-like protein isoform 3 |
Synonyms | UNQ720/PRO1385 |
Description | FUNCTION: Molecular chaperone which facilitates proper subunit assembly and surface trafficking of alpha-7 (CHRNA7) and alpha-8 (CHRNA8) nicotinic acetylcholine receptors . May also promote functional expression of homomeric serotoninergic 5-HT3 receptors, and of heteromeric acetylcholine receptors alpha-3/beta-2, alpha-3/beta-4, alpha-4/beta-2 and alpha-4/beta-4. . |
Accessions | E9PKX8 Q7Z5B4 E9PK46 ENST00000531450.1 E9PNI0 A0A0S2Z6D3 ENST00000528463.5 ENST00000309737.11 [Q7Z5B4-1] ENST00000425599.6 [Q7Z5B4-6] ENST00000335425.7 [Q7Z5B4-3] ENST00000419822.2 [Q7Z5B4-2] ENST00000343202.8 [Q7Z5B4-5] A0A0S2Z607 A0A0S2Z5U4 ENST00000526962.1 |