Name | Number of supported studies | Average coverage | |
---|---|---|---|
basal cell | 13 studies | 44% ± 19% | |
keratinocyte | 5 studies | 67% ± 27% | |
myoepithelial cell | 3 studies | 79% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 60% | 25375.23 | 277 / 459 | 43% | 291.50 | 486 / 1118 |
esophagus | 35% | 29503.81 | 511 / 1445 | 62% | 3412.82 | 114 / 183 |
tonsil | 0% | 0 | 0 / 0 | 91% | 7776.38 | 41 / 45 |
skin | 72% | 246677.37 | 1308 / 1809 | 16% | 839.50 | 74 / 472 |
uterus | 1% | 967.93 | 2 / 170 | 51% | 2987.59 | 232 / 459 |
prostate | 18% | 1350.29 | 43 / 245 | 26% | 38.74 | 130 / 502 |
lung | 0% | 9.52 | 1 / 578 | 28% | 699.93 | 325 / 1155 |
bladder | 0% | 0 | 0 / 21 | 25% | 1044.61 | 126 / 504 |
pancreas | 0% | 23.05 | 1 / 328 | 11% | 148.14 | 19 / 178 |
thymus | 0% | 32.17 | 2 / 653 | 9% | 149.92 | 56 / 605 |
ovary | 0% | 0 | 0 / 180 | 10% | 12.32 | 41 / 430 |
intestine | 0% | 5.24 | 1 / 966 | 4% | 65.77 | 20 / 527 |
adipose | 2% | 571.22 | 23 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 1% | 241.11 | 15 / 1335 | 0% | 0 | 0 / 0 |
liver | 0% | 0 | 0 / 226 | 0% | 0.36 | 2 / 406 |
muscle | 0% | 46.39 | 3 / 803 | 0% | 0 | 0 / 0 |
kidney | 0% | 0 | 0 / 89 | 0% | 0.39 | 3 / 901 |
stomach | 0% | 18.26 | 1 / 359 | 0% | 0 | 0 / 286 |
brain | 0% | 8.83 | 2 / 2642 | 0% | 0.09 | 1 / 705 |
heart | 0% | 25.09 | 1 / 861 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
adrenal gland | 0% | 0 | 0 / 258 | 0% | 0 | 0 / 230 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030216 | Biological process | keratinocyte differentiation |
GO_0008544 | Biological process | epidermis development |
GO_0030855 | Biological process | epithelial cell differentiation |
GO_0042633 | Biological process | hair cycle |
GO_0045109 | Biological process | intermediate filament organization |
GO_0045110 | Biological process | intermediate filament bundle assembly |
GO_0048863 | Biological process | stem cell differentiation |
GO_0045178 | Cellular component | basal part of cell |
GO_0005856 | Cellular component | cytoskeleton |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005882 | Cellular component | intermediate filament |
GO_0001533 | Cellular component | cornified envelope |
GO_0005829 | Cellular component | cytosol |
GO_0045095 | Cellular component | keratin filament |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005200 | Molecular function | structural constituent of cytoskeleton |
GO_1990254 | Molecular function | keratin filament binding |
GO_0005515 | Molecular function | protein binding |
Gene name | KRT14 |
Protein name | Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14) |
Synonyms | |
Description | FUNCTION: The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. . |
Accessions | P02533 ENST00000167586.7 |