Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 69% | 14285.14 | 226 / 328 | 90% | 103.98 | 161 / 178 |
thymus | 42% | 7165.69 | 274 / 653 | 95% | 211.76 | 576 / 605 |
esophagus | 38% | 64743.36 | 556 / 1445 | 97% | 640.88 | 178 / 183 |
breast | 28% | 5181.81 | 129 / 459 | 94% | 300.59 | 1050 / 1118 |
stomach | 30% | 5258.81 | 107 / 359 | 91% | 138.24 | 261 / 286 |
intestine | 26% | 5948.99 | 252 / 966 | 95% | 141.38 | 500 / 527 |
prostate | 18% | 3016.23 | 44 / 245 | 94% | 139.18 | 474 / 502 |
tonsil | 0% | 0 | 0 / 0 | 96% | 658.43 | 43 / 45 |
ovary | 0% | 0 | 0 / 180 | 90% | 122.37 | 388 / 430 |
lung | 0% | 22.15 | 1 / 578 | 87% | 244.51 | 1002 / 1155 |
skin | 72% | 222163.90 | 1307 / 1809 | 14% | 33.72 | 65 / 472 |
uterus | 1% | 2239.28 | 2 / 170 | 83% | 323.36 | 383 / 459 |
bladder | 0% | 0 | 0 / 21 | 78% | 169.26 | 392 / 504 |
liver | 15% | 2274.24 | 33 / 226 | 62% | 71.87 | 252 / 406 |
heart | 59% | 18891.73 | 508 / 861 | 0% | 0 | 0 / 0 |
kidney | 6% | 812.43 | 5 / 89 | 38% | 30.55 | 343 / 901 |
eye | 0% | 0 | 0 / 0 | 8% | 9.16 | 6 / 80 |
adrenal gland | 2% | 406.77 | 4 / 258 | 4% | 3.38 | 10 / 230 |
adipose | 1% | 506.52 | 15 / 1204 | 0% | 0 | 0 / 0 |
brain | 0% | 27.29 | 5 / 2642 | 0% | 0.37 | 3 / 705 |
blood vessel | 0% | 184.45 | 5 / 1335 | 0% | 0 | 0 / 0 |
muscle | 0% | 61.89 | 2 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0030216 | Biological process | keratinocyte differentiation |
GO_0034332 | Biological process | adherens junction organization |
GO_0018149 | Biological process | peptide cross-linking |
GO_0008544 | Biological process | epidermis development |
GO_0003223 | Biological process | ventricular compact myocardium morphogenesis |
GO_0042060 | Biological process | wound healing |
GO_0045109 | Biological process | intermediate filament organization |
GO_0002934 | Biological process | desmosome organization |
GO_0045104 | Biological process | intermediate filament cytoskeleton organization |
GO_0086091 | Biological process | regulation of heart rate by cardiac conduction |
GO_0098911 | Biological process | regulation of ventricular cardiac muscle cell action potential |
GO_0090136 | Biological process | epithelial cell-cell adhesion |
GO_0150105 | Biological process | protein localization to cell-cell junction |
GO_0043588 | Biological process | skin development |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0086073 | Biological process | bundle of His cell-Purkinje myocyte adhesion involved in cell communication |
GO_0005886 | Cellular component | plasma membrane |
GO_0005916 | Cellular component | fascia adherens |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005882 | Cellular component | intermediate filament |
GO_0001533 | Cellular component | cornified envelope |
GO_0005912 | Cellular component | adherens junction |
GO_0101003 | Cellular component | ficolin-1-rich granule membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0030057 | Cellular component | desmosome |
GO_0014704 | Cellular component | intercalated disc |
GO_0016323 | Cellular component | basolateral plasma membrane |
GO_0005634 | Cellular component | nucleus |
GO_0005080 | Molecular function | protein kinase C binding |
GO_0086083 | Molecular function | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication |
GO_0005200 | Molecular function | structural constituent of cytoskeleton |
GO_0005198 | Molecular function | structural molecule activity |
GO_0097110 | Molecular function | scaffold protein binding |
GO_0003723 | Molecular function | RNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | DSP |
Protein name | DSP variant protein Desmoplakin Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) |
Synonyms | protein variant |
Description | FUNCTION: Major high molecular weight protein of desmosomes. Regulates profibrotic gene expression in cardiomyocytes via activation of the MAPK14/p38 MAPK signaling cascade and increase in TGFB1 protein abundance (By similarity). . |
Accessions | ENST00000683682.2 ENST00000379802.8 [P15924-1] P15924 ENST00000418664.2 [P15924-2] ENST00000710359.1 [P15924-3] Q4LE79 G1UI31 A0A804HL18 |